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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2014; 04(04): 120-125
DOI: 10.1055/s-0040-1703850
Review Article

ROLE OF PHYTOCHEMICALS IN ORAL POTENTIALLY MALIGNANT DISORDERS : A REVIEW

Ananya Madiyal
1   Post Graduates, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore - 575 018, India.
,
Vidya Ajila
2   Reader, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore - 575 018, India.
,
Subhas G Babu
3   Professor & HOD, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore - 575 018, India.
,
Shruthi Hedge
4   Lecturers, Department of Oral Medicine & Radiology, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore - 575 018, India.
,
Harini Keshavaiah
5   Lecturers, Department of Oral Medicine & Radiology,Department of Periodontics, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore - 575 018, India.
,
Priyadharshini Alva M.
6   Post Graduates, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore - 575 018, India.
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Abstract

Oral cancer is a major global health concern and poses a challenge to diagnostic and therapeutic aspects of healthcare services. Various oral lesions like leukoplakia, erythroplakia, lichen planus and oral submucus fibrosis categorized as orally potential malignant disorders have shown increased incidence of malignant transformation. Free radicals are highly reactive chemical species with capacity to damage nucleic acids, proteins and lipids and bring about changes of clinical significance. Antioxidants help in scavenging these free radicals and prevent disease progression. Naturally occurring phytochemicals play an important role in preventing oxidative stress and protect the cells from damage by free radicals.

Keywords

Antioxidants - phytochemicals - oral potentially malignant disorders - chemoprevention


Publication History

Article published online:
26 April 2020

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