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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2011; 01(01/03): 72-74
DOI: 10.1055/s-0040-1703527
Case Report

NECROBIOTIC XANTHOGRANULOMA PRESENTING AS A CLINICAL VARIANT WITHOUT PARAPROTEINEMIA

Michelle Mathias
Associate Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Derlakatte, Mangalore ,INDIA
,
Harish S Permi
Assistant Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Derlakatte, Mangalore ,INDIA
,
Padma Shetty
Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Derlakatte, Mangalore ,INDIA
,
Jayaprakash Shetty K.
Professor and HOD, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Derlakatte, Mangalore ,INDIA
,
B. S. Girish
Associate Professor, Department of Dermatology, K.S. Hegde Medical Academy, Nitte University, Derlakatte, Mangalore ,INDIA
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Abstract

Necrobiotic xanthogranuloma is a rare granulomatous disease involving skin and subcutaneous tissues. A 61 year old woman presented with a 5 year history of enlarging plaques around both eyelids.it was associated with diminished vision in both eyes. The lesions are often bilateral,symmetrical and ophthalmologic complications are observed. A histopathological examination showed features of necrobiotic xanthogranuloma. Necrobiotic xanthogranuloma is usually associated with paraproteinemia which was not seen in our case.The pathogenesis remains unclear. Although there is no first line of treatment, reports have shown variable benefits with chemotherapeutic agent and steroids.

Keywords

necrobiotic xanthogranuloma - necrobiosis


Publication History

Article published online:
20 February 2020

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