CC BY-NC-ND 4.0 · Eur J Dent 2012; 06(01): 095-100
DOI: 10.1055/s-0039-1698936
Original Article
Dental Investigation Society

Severe periodontal destruction in a patient with advanced anemia: A case report

Hasan Hatipoglu
1   Research and Training Hospital, Dental Clinic/ Periodontology, Dumlupınar University, Kutahya, TURKIYE
,
Mujgan Gungor Hatipoglu
2   Research and Training Hospital, Dental Clinic/ Oral Diagnosis ve Radiology, Dumlupınar University, Kütahya, TURKIYE
,
L Berna Cagirankaya
3   Department of Oral Diagnosis and Radiology, Faculty of Dentistry, Hacettepe University, Ankara, TURKIYE
,
Feriha Caglayan
4   Department of Periodontology, Faculty of Dentistry, Hacettepe University, Ankara, TURKIYE
› Author Affiliations
Further Information

Publication History

Publication Date:
30 September 2019 (online)

ABSTRACT

Anemia is a worldwide health problem that manifests in different types. This illness has some causes, which affect body health generally. Studies have shown that some anemia types make humans more sensitive to infections

A 23-year-old woman was referred to our clinic with complaints about tooth mobility. Generalized severe alveolar bone loss was verified by a radiographic examination. After a comprehensive clinical examination and taking her medical history, we decided to schedule a medical consultation with a physician. Medical consultation revealed that the patient suffered from severe anemia. Her periodontal treatment was modified because of her systemic situation. After treatment, the patient was monitored for one year. Her periodontal and systemic statuses were stable during this period

In this case report, severe periodontal destruction was observed in a patient with severe iron and B12 deficiency anemia. (Eur J Dent 2012;6:95-100)

 
  • References

  • 1 Page RC: The pathology of periodontal diseases may affect systemic diseases: inversion of a paradigm. Ann Periodontol 1998;3:108-120.
  • 2 Lainson PA., Brady PP, Fraleigh CM. Anemia A systemic Cause of Periodontal disease? J Periodontol 1968;9:35-38.
  • 3 Erdemir EO, Nalcaci R, Caglayan O. Evaluation of systemic markers related to anemia of chronic disease in the peripheral blood of smokers and non-smokers with chronic periodontitis. Eur J Dent 2008;2:102-109.
  • 4 Goldstein H. Systemic and Blood-Pictures Findings in Several Hundred Periclasia-Free and Periclasia-Involved Individuals. J Dent Res 1937;16:320.
  • 5 Gokhale SR, Sumanth S, Padhye AM. Evaluation of blood parameters in patients with chronic periodontitis for signs of anemia. J Periodontol 2010;81:1202-1206.
  • 6 Pradeep AR, Sharma A, Arjun Raju P. Anemia of Chronic Disease and Chronic Periodontitis: Does Periodontal Therapy Have Effect on Anemic Status. J Periodontol 2011;82:388-394.
  • 7 Agarwal N, Kumar VS, Gujjari SA. Effect of periodontal therapy on hemoglobin and erythrocyte levels in chronic generalized periodontitis patients: An interventional study. J Indian Soc Periodontol 2009;13:6-11.
  • 8 Lu S-Yu, Eng HL. Dramatic recovery from severe anemia by resolution of severe periodontitis. J Dent Sci 2010;5:41−46.
  • 9 Hutter JW, Van der Velden U, Varoufaki A, Huffels RAM, Hek FJ, Loos BG. Lower numbers of erythrocytes and lower levels of hemoglobin in periodontitis patients compared to control subjects. J Clin Periodontol 2001;28:930-936.
  • 10 Salvi GE, Lawrence HP, Offenbacher S, Beck JD. Influence of risk factors on the pathogenesis of periodontitis. Periodontol 2000 1997;14:173-201.
  • 11 Seymour RA, Heasman PA. Drugs, diseases, and the periodontium. Oxford: Oxford University Press, 1992:19-147.
  • 12 Davies RM. Periodontal Manifestations of systemic disease. In: H.J. Jones and D.K. Mason, Eds, Oral manifestations of systemic disease. London: W. B. Saunders, 1980:514-529.
  • 13 Katz J. Dental Correlation Nutritional Disorders. In: Kaye, D. & Rose, L.F., Internal Medicine for Dentistry, 2. ed, eds. St Louis: Mosby Company, 1990:978-985.
  • 14 Carranza, F.A., Influence of systemic diseases on the periodontium. In: Carranza, FA, Newmann MG. Eds. Clinical Periodontology. 8th Ed, Philadelphia: WB Saunders, 1996:185-205.
  • 15 Ferguson MM, Dagg JH. Nutritional Disorders. In: H.J. Jones and D.K. Mason, Eds, Oral manifestations of systemic disease. London: W. B. Saunders, 1980:211-228.
  • 16 Wray D. and Dagg JH. Diseases of the blood and bloodforming organs. In: H.J. Jones and D.K. Mason, Eds, Oral manifestations of systemic disease, London: W. B. Saunders, 1980:262-296.
  • 17 Pétavy-Catala C, Fontès V, Gironet N, Hüttenberger B, Lorette G, Vaillant L. Clinical manifestations of the mouth revealing Vitamin B12 deficiency before the onset of anemia. Ann Dermatol Venereol 2003;130:191-194.
  • 18 Cohen SG, Glick M. Dental Correlation, Anemia and Deficiency States. In: KayeD. & Rose LF, eds. Internal Medicine for Dentistry, 2. Ed, St Louis: Mosby Company, 1990:360-361.
  • 19 Hvas AM, Nexo E. Diagnosis and treatment of vitamin B12 deficiency-an update. Haematologica 2006;91:1506-1512.
  • 20 DeRossi SS, Raghavendra S. Anemia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:131-141.
  • 21 Becks H., Wainwraight WW, Morgan AF. Comparative study of oral changes in dogs due to deficiencies of pantothenic acid, nicotinic acid and unknowns of B vitamin complex. Am J Orthod Oral Surg 1943;29:183–207.
  • 22 Maggini S, Wintergerst ES, Beveridge S, Hornig DH. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr 2007;98 Suppl 1:S29-35.
  • 23 Tamura J, Kubota K, Murakami H, Sawamura M, Matsushima T, Tamura T, Saitoh T, Kurabayshi H, Naruse T. Immunomodulation by vitamin B12: augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment. Clin Exp Immunol 1999;116:28-32.
  • 24 Weiss G. Modification of iron regulation by the inflammatory response. Best Pract Res Clin Haematol 2005;18:183-201.
  • 25 Barry W.E. Iron Deficiency Anemia and Anemia of Chronic Disease In: KayeD. & Rose LF, eds. Internal Medicine for Dentistry, 2. Ed, St Louis: Mosby Company, 1990:285-287.
  • 26 Ward RJ, Crichton RR, Taylor DL, Corte LD, Srai SK, Dexter DT. Iron and the immune system. J Neural Transm 2011;118:315-328.
  • 27 Armitage GC. Development of a Classification System for Periodontal Diseases and Conditions. Ann Periodontol 1999;4:1-6.