Download PDF
CC BY-NC-ND 4.0 · Eur J Dent 2007; 01(04): 192-194
DOI: 10.1055/s-0039-1698338
Editorial
Dental Investigation Society

Platelet Rich Plasma: Myth or Reality?

Hom-Lay Wang
,
Gustavo Avila
Further Information

Publication History

Publication Date:
27 September 2019 (online)

Also available at
  PDF Download Permissions and Reprints
 

  • References

  • 1 Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 85: 638-646
    CrossrefPubMedSearch in Google Scholar
  • 2 Petrungaro PS. Using platelet-rich plasma to accelerate soft tissue maturation in esthetic periodontal surgery. Compend Contin Educ Dent 2001; 22: 729-732 734, 736 passim; quiz 746
    PubMedSearch in Google Scholar
  • 3 Bennett NT, Schultz GS. Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg 1993; 165: 728-737.
    CrossrefPubMedSearch in Google Scholar
  • 4 Sanchez AR, Sheridan pj, Kupp LI. Is platelet-rich plasma the perfect enhancement factor? A current review.. Int J Oral Maxillofac Implants 2003; 18: 093-103
    Search in Google Scholar
  • 5 El-Sharkawy H, Kantarci A, Deady J, Hasturk H, Liu H, Alshahat M. et al Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol 2007; 78: 661-669
    CrossrefPubMedSearch in Google Scholar
  • 6 Fernandez-Barbero JE, Galindo-Moreno P, Avila-Ortiz G, Caba OP, Sanchez-Fernandez E, Wang HL. Flow cytometric and morphological characterization of platelet-rich plasma gel. Clin Oral Implants Res 2006; 17: 687-693
    CrossrefPubMedSearch in Google Scholar
  • 7 Anitua E. Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 1999; 14: 529-535
    Search in Google Scholar
  • 8 Weibrich G, Kunz-Kostomanolakis M, Loos AH, Wagner W. Correlation of platelet concentration in platelet-rich plasma to the extraction method, age, sex, and platelet count of the donor. Int J Oral Maxillofac Implants 2001; 16: 693-699
    Search in Google Scholar
  • 9 Jakse N, Tangl S, Gilli R, Berghold A, Lorenzoni M, Eskici A. et al Influence of PRP on autogenous sinus grafts. An experimental study on sheep. Clin Oral Implants Res 2003; 14: 578-583
    CrossrefPubMedSearch in Google Scholar
  • 10 Freymiller EG, Aghaloo TL. Platelet-rich plasma: ready or not. J Oral Maxillofac Surg 2004; 62: 484-488
    CrossrefPubMedSearch in Google Scholar
  • 11 Whitman DH, Berry RL, Green DM. Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 1997; 55: 1294-1299
    CrossrefPubMedSearch in Google Scholar
  • 12 Carlson NE, Roach RB. Jr. Platelet-rich plasma: clinical applications in dentistry. J Am Dent Assoc (1939) 2002; 133: 1383-1386
    CrossrefPubMedSearch in Google Scholar
  • 13 Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004; 91: 004-015
    Thieme ConnectPubMedSearch in Google Scholar
  • 14 Lucarelli E, Donati D, Cenacchi AA, Fornasari PM. Bone reconstruction of large defects using bone marrow derived autologous stem cells. Transfus Apher Sci 2004; 30: 169-174
    CrossrefPubMedSearch in Google Scholar
  • 15 Hanna R, Trejo PM, Weltman M, Nakamura RL. Treatment of intrabony defects with bovine-derived xenograft alone and in combination with platelet-rich plasma: a randomized clinical trial. J Periodontol 2004; 75: 1668-1677
    CrossrefPubMedSearch in Google Scholar
  • 16 Okuda K, Tai H, Tanabe K, Suzuki H, Sato T. Kawase T, et al. Platelet-rich plasma combined with a porous hydroxyapatite graft for the treatment of intrabony periodontal defects in humans: a comparative controlled clinical study. J Periodontol 2005; 76: 890-898
    CrossrefPubMedSearch in Google Scholar
  • 17 Lekovic V, Camargo PM, Weinlaender M, Vasilic N, Kenney EB. Comparison of platelet-rich plasma, bovine porous bone mineral, and guided tissue regeneration versus platelet-rich plasma and bovine porous bone mineral in the treatment of intrabony defects: a reentry study. J Periodontol 2002; 73: 198-205
    CrossrefPubMedSearch in Google Scholar
  • 18 Sammartino G, Tia M, Marenzi G, di Lauro AE, D’Agostino E, Claudio PP. Use of autologous platelet-rich plasma (PRP) in periodontal defect treatment after extraction of impacted mandibular third molars. J Oral Maxillofac Surg 2005; 63: 766-770
    CrossrefPubMedSearch in Google Scholar
  • 19 Monov G, Fuerst G, Tepper G, Watzak G. The effect of platelet-rich plasma upon implant stability measured by resonance frequency analysis in the lower anterior mandibles. Clin Oral Implants Res 2005; 16: 461-465
    CrossrefPubMedSearch in Google Scholar
  • 20 Kim SG, Kim WK, Park JC, Kim HJ. A comparative study of osseointegration of Avana implants in a demineralized freeze-dried bone alone or with platelet-rich plasma. J Oral Maxillofac Surg 2002; 60: 1018-1025
    CrossrefPubMedSearch in Google Scholar
  • 21 Kim SG, Chung CH, Kim YK, Park JC, Lim SC. et al. Use of particulate dentin-plaster of Paris combination with/ without platelet-rich plasma in the treatment of bone defects around implants. Int J Oral Maxillofac Implants 2002; 17: 086-094
    Search in Google Scholar
  • 22 Kassolis JD, Reynolds MA. Evaluation of the adjunctive benefits of platelet-rich plasma in subantral sinus augmentation. J Craniofac Surg 2005; 16: 280-287
    CrossrefPubMedSearch in Google Scholar
  • 23 Butterfield KJ, Bennett J, Gronowicz G, Adams D. Effect of platelet-rich plasma with autogenous bone graft for maxillary sinus augmentation in a rabbit model. J Oral Maxillofac Surg 2005; 63: 370-376
    CrossrefPubMedSearch in Google Scholar
  • 24 Grageda E, Lozada JL, Boyne PJ, Caplanis N, McMillan PJ. Bone formation in the maxillary sinus by using platelet-rich plasma: an experimental study in sheep. J Oral Implantol 2005; 31: 002-017
    CrossrefPubMedSearch in Google Scholar
  • 25 Furst G, Gruber R, Tangl S, Zechner W, Haas R, Mailath G. et al Sinus grafting with autogenous platelet-rich plasma and bovine hydroxyapatite. A histomorphometric study in minipigs. Clin Oral Implants Res 2003; 14: 500-508
    CrossrefPubMedSearch in Google Scholar
  • 26 Wiltfang J, Schlegel KA, Schultze-Mosgau S, Nkenke E, Zimmermann R, Kessler P. Sinus floor augmentation with beta-tricalciumphosphate (beta-TCP): does platelet-rich plasma promote its osseous integration and degradation. Clin Oral Implants Res 2003; 14: 213-218
    CrossrefPubMedSearch in Google Scholar
  • 27 Thorwarth M, Wehrhan F, Schultze-Mosgau S. Wiltfang J, Schlegel KA. PRP modulates expression of bone matrix proteins in vivo without long-term effects on bone formation. Bone 2006; 38: 030-040
    Search in Google Scholar
  • 28 Kassolis JD, Rosen PS, Reynolds MA. Alveolar ridge and sinus augmentation utilizing platelet-rich plasma in combination with freeze-dried bone allograft: case series. J Periodontol 2000; 71: 1654-1661
    CrossrefPubMedSearch in Google Scholar
  • 29 Froum SJ, Wallace SS, Tarnow DP, Cho SC. Effect of platelet-rich plasma on bone growth and osseointegration in human maxillary sinus grafts: three bilateral case reports. Int J Periodontics Restorative Dent 2002; 22: 045-053
    Search in Google Scholar
  • 30 Wiltfang JP, Kloss FR, Kessler PW, Nkenke E, Schultze- Mosgau S, Zimmermann R. et al. Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical-size defects. An animal experiment. Clin Oral Implants Res 2004; 15: 187-193
    CrossrefPubMedSearch in Google Scholar
  • 31 Philippart P, Daubie V, Pochet R. Sinus grafting using recombinant human tissue factor, platelet-rich plasma gel, autologous bone, and anorganic bovine bone mineral xenograft: histologic analysis and case reports. nt J Oral Maxillofac Implants 2005; 20: 274-281
    Search in Google Scholar
  • 32 Mazor Z, Peleg M, Garg AK, Luboshitz J. Platelet-rich plasma for bone graft enhancement in sinus floor augmentation with simultaneous implant placement: patient series study. Implant Dent 2004; 13: 065-072
    CrossrefPubMedSearch in Google Scholar
  • 33 Rosenberg ES, Torosian J. Sinus grafting using plateletrich plasma--initial case presentation. Pract Proced Aesthet Dent 2000; 12: 843-850 quiz 852
    Search in Google Scholar
  • 34 Thor A, Wannfors K, Sennerby L, Rasmusson L. Reconstruction of the severely resorbed maxilla with autogenous bone, platelet-rich plasma, and implants: 1- year results of a controlled prospective 5-year study. Clin Implant Dent Relat Res 2005; 7: 209-220
    CrossrefPubMedSearch in Google Scholar
  • 35 Landesberg RC, Moses M, Karpatkin M. Risks of using platelet rich plasma gel. J Oral Maxillofac Surg 1998; 56: 1116-1117
    PubMedSearch in Google Scholar