Subscribe to RSS
DOI: 10.1055/s-0039-1695050
Pleural Disease in Women
Publication History
Publication Date:
16 September 2019 (online)
Abstract
There are several pleural diseases that occur either predominantly or exclusively in females. Most of these entities are related to obstetric or gynecological conditions. In this article, we will provide an overview of Meigs' syndrome, ovarian hyperstimulation syndrome, endometriosis, catamenial pneumothorax, catamenial hemothorax, pleural effusions that occur in the peripartum period, lymphangioleiomyomatosis, and malignant pleural effusions related to breast cancer. As most of these diagnoses are rare, considerable expertise is required to identify, diagnose, and manage these patients. The aim of this article is to present an overview of the most common forms of pleural disease affecting women, and to provide an easy reference source on current best practice.
-
References
- 1 Meigs JV, Dresser R. Carcinoma of the cervix treated by the Roentgen ray and radium. Ann Surg 1937; 106 (04) 653-667
- 2 Lurie S. Meigs' syndrome: the history of the eponym. Eur J Obstet Gynecol Reprod Biol 2000; 92 (02) 199-204
- 3 Riker D, Goba D. Ovarian mass, pleural effusion, and ascites: revisiting Meigs syndrome. J Bronchology Interv Pulmonol 2013; 20 (01) 48-51
- 4 Agranoff D, May D, Jameson C, Knowles GK. Pleural effusion and a pelvic mass. Postgrad Med J 1998; 74 (871) 265-267
- 5 Meigs JV. Pelvic tumors other than fibromas of the ovary with ascites and hydrothorax. Obstet Gynecol 1954; 3 (05) 471-486
- 6 Shiau CS, Chang MY, Hsieh CC, Hsieh TT, Chiang CH. Meigs' syndrome in a young woman with a normal serum CA-125 level. Chang Gung Med J 2005; 28 (08) 587-591
- 7 Abramov Y, Anteby SO, Fasouliotis SJ, Barak V. Markedly elevated levels of vascular endothelial growth factor, fibroblast growth factor, and interleukin 6 in Meigs syndrome. Am J Obstet Gynecol 2001; 184 (03) 354-355
- 8 Ishiko O, Yoshida H, Sumi T, Hirai K, Ogita S. Vascular endothelial growth factor levels in pleural and peritoneal fluid in Meigs' syndrome. Eur J Obstet Gynecol Reprod Biol 2001; 98 (01) 129-130
- 9 Kirschner PA. Porous diaphragm syndromes. Chest Surg Clin N Am 1998; 8 (02) 449-472
- 10 Meigs J, Armstrong SH, Hamilton HH. A further contribution to the syndrome of fibroma of the ovary with fluid in the abdomen and chest, Meigs' syndrome. Am J Obstet Gynecol 1943; 46: 19-37
- 11 Jimerson SD. Pseudo-Meigs's syndrome. An unusual case with analysis of the effusions. Obstet Gynecol 1973; 42 (04) 535-537
- 12 Krenke R, Maskey-Warzechowska M, Korczynski P. , et al. Pleural effusion in Meigs' syndrome-transudate or exudate?: systematic review of the literature. Medicine (Baltimore) 2015; 94 (49) e2114
- 13 Hurlow RA, Greening WP, Krantz E. Ascites and hydrothorax in association with struma ovarii. Br J Surg 1976; 63 (02) 110-112
- 14 Neustadt JE, Levy RC. Hemorrhagic pleural effusion in Meig's syndrome. JAMA 1968; 204 (01) 81-82
- 15 Patsner B. Meigs syndrome and “false positive” preoperative serum CA-125 levels: analysis of ten cases. Eur J Gynaecol Oncol 2000; 21 (04) 362-363
- 16 Lin JY, Angel C, Sickel JZ. Meigs syndrome with elevated serum CA 125. Obstet Gynecol 1992; 80 (3, Pt 2): 563-566
- 17 Nemeth AJ, Patel SK. Meigs syndrome revisited. J Thorac Imaging 2003; 18 (02) 100-103
- 18 Delvigne A, Rozenberg S. Review of clinical course and treatment of ovarian hyperstimulation syndrome (OHSS). Hum Reprod Update 2003; 9 (01) 77-96
- 19 Di Carlo C, Savoia F, Ferrara C, Tommaselli GA, Bifulco G, Nappi C. Case report: a most peculiar family with spontaneous, recurrent ovarian hyperstimulation syndrome. Gynecol Endocrinol 2012; 28 (08) 649-651
- 20 Li HW, Lee VC, Lau EY, Yeung WS, Ho PC, Ng EH. Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment. J Assist Reprod Genet 2014; 31 (02) 205-211
- 21 Nastri CO, Ferriani RA, Rocha IA, Martins WP. Ovarian hyperstimulation syndrome: pathophysiology and prevention. J Assist Reprod Genet 2010; 27 (2–3): 121-128
- 22 Nastri CO, Teixeira DM, Moroni RM, Leitão VM, Martins WP. Ovarian hyperstimulation syndrome: pathophysiology, staging, prediction and prevention. Ultrasound Obstet Gynecol 2015; 45 (04) 377-393
- 23 Light RW, Lee G. Textbook of Pleural Diseases. 2nd ed. London, FL: Hodder Arnold Publication; 2008
- 24 Chen CD, Wu MY, Chen HF, Chen SU, Ho HN, Yang YS. Prognostic importance of serial cytokine changes in ascites and pleural effusion in women with severe ovarian hyperstimulation syndrome. Fertil Steril 1999; 72 (02) 286-292
- 25 Goldsman MP, Pedram A, Dominguez CE, Ciuffardi I, Levin E, Asch RH. Increased capillary permeability induced by human follicular fluid: a hypothesis for an ovarian origin of the hyperstimulation syndrome. Fertil Steril 1995; 63 (02) 268-272
- 26 Wang TH, Horng SG, Chang CL. , et al. Human chorionic gonadotropin-induced ovarian hyperstimulation syndrome is associated with up-regulation of vascular endothelial growth factor. J Clin Endocrinol Metab 2002; 87 (07) 3300-3308
- 27 Ajonuma LC. Is vascular endothelial growth factor (VEGF) the main mediator in ovarian hyperstimulation syndrome (OHSS)?. Med Hypotheses 2008; 70 (06) 1174-1178
- 28 Ajonuma LC, Ajuonuma MU, Ajuonuma BC, Ogbedeagu VM, Ajuonuma JU, Chukwu CL. EG-VEGF concentrations may predict OHSS. Fertil Steril 2011; 95 (07) e37 , author reply e38
- 29 Evbuomwan IO, Davison JM, Murdoch AP. Coexistent hemoconcentration and hypoosmolality during superovulation and in severe ovarian hyperstimulation syndrome: a volume homeostasis paradox. Fertil Steril 2000; 74 (01) 67-72
- 30 Light RW. Pleural Diseases, 5th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2007
- 31 Elchalal U, Schenker JG. The pathophysiology of ovarian hyperstimulation syndrome--views and ideas. Hum Reprod 1997; 12 (06) 1129-1137
- 32 Carizza C, Abdelmassih V, Abdelmassih S. , et al. Cabergoline reduces the early onset of ovarian hyperstimulation syndrome: a prospective randomized study. Reprod Biomed Online 2008; 17 (06) 751-755
- 33 Fábregues F, Peñarrubia J, Vidal E, Casals G, Vanrell JA, Balasch J. Oocyte quality in patients with severe ovarian hyperstimulation syndrome: a self-controlled clinical study. Fertil Steril 2004; 82 (04) 827-833
- 34 Lee KH, Kim SH, Jee BC. , et al. Comparison of clinical characteristics between early and late patterns in hospitalized patients with ovarian hyperstimulation syndrome. Fertil Steril 2010; 93 (07) 2274-2280
- 35 Lyons CA, Wheeler CA, Frishman GN, Hackett RJ, Seifer DB, Haning Jr RV. Early and late presentation of the ovarian hyperstimulation syndrome: two distinct entities with different risk factors. Hum Reprod 1994; 9 (05) 792-799
- 36 Mathur RS, Akande AV, Keay SD, Hunt LP, Jenkins JM. Distinction between early and late ovarian hyperstimulation syndrome. Fertil Steril 2000; 73 (05) 901-907
- 37 Papanikolaou EG, Pozzobon C, Kolibianakis EM. , et al. Incidence and prediction of ovarian hyperstimulation syndrome in women undergoing gonadotropin-releasing hormone antagonist in vitro fertilization cycles. Fertil Steril 2006; 85 (01) 112-120
- 38 Papanikolaou EG, Tournaye H, Verpoest W. , et al. Early and late ovarian hyperstimulation syndrome: early pregnancy outcome and profile. Hum Reprod 2005; 20 (03) 636-641
- 39 Qasim SM, Karacan M, Kemmann E. An eight year review of hospitalization for ovarian hyperstimulation syndrome. Clin Exp Obstet Gynecol 1997; 24 (02) 49-52
- 40 Gregory WT, Patton PE. Isolated pleural effusion in severe ovarian hyperstimulation: a case report. Am J Obstet Gynecol 1999; 180 (6, Pt 1): 1468-1471
- 41 Rabinerson D, Shalev J, Royburt M, Ben-Rafael Z, Dekel A. Severe unilateral hydrothorax as the only manifestation of the ovarian hyperstimulation syndrome. Gynecol Obstet Invest 2000; 49 (02) 140-142
- 42 Lobo DN, Stanga Z, Aloysius MM. , et al. Effect of volume loading with 1 liter intravenous infusions of 0.9% saline, 4% succinylated gelatine (Gelofusine) and 6% hydroxyethyl starch (Voluven) on blood volume and endocrine responses: a randomized, three-way crossover study in healthy volunteers. Crit Care Med 2010; 38 (02) 464-470
- 43 McClelland DB. ABC of transfusion. Human albumin solutions. BMJ 1990; 300 (6716): 35-37
- 44 Youssef MA, Al-Inany HG, Evers JL, Aboulghar M. Intra-venous fluids for the prevention of severe ovarian hyperstimulation syndrome. Cochrane Database Syst Rev 2011; (02) CD001302
- 45 Abramov Y, Elchalal U, Schenker JG. Pulmonary manifestations of severe ovarian hyperstimulation syndrome: a multicenter study. Fertil Steril 1999; 71 (04) 645-651
- 46 Augoulea A, Lambrinoudaki I, Christodoulakos G. Thoracic endometriosis syndrome. Respiration 2008; 75 (01) 113-119
- 47 Hasdemir PS, Ikiz N, Ozcakir HT, Kara E, Guvenal T. Endometriosis associated with relapsing ascites and pleural effusions. J Obstet Gynaecol 2015; 35 (04) 419
- 48 Muneyyirci-Delale O, Neil G, Serur E, Gordon D, Maiman M, Sedlis A. Endometriosis with massive ascites. Gynecol Oncol 1998; 69 (01) 42-46
- 49 Bhojawala J, Heller DS, Cracchiolo B, Sama J. Endometriosis presenting as bloody pleural effusion and ascites-report of a case and review of the literature. Arch Gynecol Obstet 2000; 264 (01) 39-41
- 50 Shepard MK, Mancini MC, Campbell Jr GD, George R. Right-sided hemothorax and recurrent abdominal pain in a 34-year-old woman. Chest 1993; 103 (04) 1239-1240
- 51 Lillington GA, Mitchell SP, Wood GA. Catamenial pneumothorax. JAMA 1972; 219 (10) 1328-1332
- 52 Maurer ER, Schaal JA, Mendez Jr FL. Chronic recurring spontaneous pneumothorax due to endometriosis of the diaphragm. J Am Med Assoc 1958; 168 (15) 2013-2014
- 53 Alifano M. Catamenial pneumothorax. Curr Opin Pulm Med 2010; 16 (04) 381-386
- 54 Alifano M, Jablonski C, Kadiri H. , et al. Catamenial and noncatamenial, endometriosis-related or nonendometriosis-related pneumothorax referred for surgery. Am J Respir Crit Care Med 2007; 176 (10) 1048-1053
- 55 Alifano M, Roth T, Broët SC, Schussler O, Magdeleinat P, Regnard JF. Catamenial pneumothorax: a prospective study. Chest 2003; 124 (03) 1004-1008
- 56 Joseph J, Sahn SA. Thoracic endometriosis syndrome: new observations from an analysis of 110 cases. Am J Med 1996; 100 (02) 164-170
- 57 Rousset-Jablonski C, Alifano M, Plu-Bureau G. , et al. Catamenial pneumothorax and endometriosis-related pneumothorax: clinical features and risk factors. Hum Reprod 2011; 26 (09) 2322-2329
- 58 Channabasavaiah AD, Joseph JV. Thoracic endometriosis: revisiting the association between clinical presentation and thoracic pathology based on thoracoscopic findings in 110 patients. Medicine (Baltimore) 2010; 89 (03) 183-188
- 59 Gourgoulianis KI, Karantanas AH, Molyvdas PA. Peripartum pleural effusion. Chest 1997; 111 (05) 1467-1468
- 60 Kocijancic I, Pusenjak S, Kocijancic K, Vidmar G. Sonographic detection of physiologic pleural fluid in normal pregnant women. J Clin Ultrasound 2005; 33 (02) 63-66
- 61 Haddad B, Barton JR, Livingston JC, Chahine R, Sibai BM. HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome versus severe preeclampsia: onset at < or =28.0 weeks' gestation. Am J Obstet Gynecol 2000; 183 (06) 1475-1479
- 62 Romanyuk V, Raichel L, Sergienko R, Sheiner E. Pneumonia during pregnancy: radiological characteristics, predisposing factors and pregnancy outcomes. J Matern Fetal Neonatal Med 2011; 24 (01) 113-117
- 63 Light RW. Pleural diseases in pregnancy. Int Pleural News 2006; 4: 6-7
- 64 Ayres MA, Sulak PJ. Pregnancy complicated by antiphospholipid antibodies. South Med J 1991; 84 (02) 266-269
- 65 Heit JA, Kobbervig CE, James AH, Petterson TM, Bailey KR, Melton III LJ. Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study. Ann Intern Med 2005; 143 (10) 697-706
- 66 Arany Z, Elkayam U. Peripartum cardiomyopathy. Circulation 2016; 133 (14) 1397-1409
- 67 Harari S, Spagnolo P, Cocconcelli E, Luisi F, Cottin V. Recent advances in the pathobiology and clinical management of lymphangioleiomyomatosis. Curr Opin Pulm Med 2018; 24 (05) 469-476
- 68 Khaddour K, Shayuk M. Lymphangioleiomyomatosis. Treasure Island, FL: StatPearls; 2019
- 69 Yu J, Astrinidis A, Howard S, Henske EP. Estradiol and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways. Am J Physiol Lung Cell Mol Physiol 2004; 286 (04) L694-L700
- 70 Xu KF, Tian X, Ryu JH. Recent advances in the management of lymphangioleiomyomatosis. F1000 Res 2018; 7: 7
- 71 Taylor JR, Ryu J, Colby TV, Raffin TA. Lymphangioleiomyomatosis. Clinical course in 32 patients. N Engl J Med 1990; 323 (18) 1254-1260
- 72 Johnson SR. Lymphangioleiomyomatosis. Eur Respir J 2006; 27 (05) 1056-1065
- 73 Almoosa KF, McCormack FX, Sahn SA. Pleural disease in lymphangioleiomyomatosis. Clin Chest Med 2006; 27 (02) 355-368
- 74 Almoosa KF, Ryu JH, Mendez J. , et al. Management of pneumothorax in lymphangioleiomyomatosis: effects on recurrence and lung transplantation complications. Chest 2006; 129 (05) 1274-1281
- 75 Young LR, Almoosa KF, Pollock-Barziv S, Coutinho M, McCormack FX, Sahn SA. Patient perspectives on management of pneumothorax in lymphangioleiomyomatosis. Chest 2006; 129 (05) 1267-1273
- 76 McCormack FX, Gupta N, Finlay GR. , et al; ATS/JRS Committee on Lymphangioleiomyomatosis. Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: lymphangioleiomyomatosis diagnosis and management. Am J Respir Crit Care Med 2016; 194 (06) 748-761
- 77 Hillerdal G. Textbook of Pleural Disease. 2nd ed. London: Hodder Arnold; 2008
- 78 Landis SH, Murray T, Bolden S, Wingo PA. Cancer statistics, 1999. CA Cancer J Clin 1999; 49 (01) 8-31 , 1
- 79 Heffner JE, Klein JS. Recent advances in the diagnosis and management of malignant pleural effusions. Mayo Clin Proc 2008; 83 (02) 235-250
- 80 Heffner JE, Nietert PJ, Barbieri C. Pleural fluid pH as a predictor of survival for patients with malignant pleural effusions. Chest 2000; 117 (01) 79-86
- 81 Thomas JM, Redding WH, Sloane JP. The spread of breast cancer: importance of the intrathoracic lymphatic route and its relevance to treatment. Br J Cancer 1979; 40 (04) 540-547
- 82 Boulanger E, Gérard L, Gabarre J. , et al. Prognostic factors and outcome of human herpesvirus 8-associated primary effusion lymphoma in patients with AIDS. J Clin Oncol 2005; 23 (19) 4372-4380
- 83 Das DK. Serous effusions in malignant lymphomas: a review. Diagn Cytopathol 2006; 34 (05) 335-347
- 84 Kocijancic I, Vidmar K, Ivanovi-Herceg Z. Chest sonography versus lateral decubitus radiography in the diagnosis of small pleural effusions. J Clin Ultrasound 2003; 31 (02) 69-74
- 85 Chian CF, Su WL, Soh LH, Yan HC, Perng WC, Wu CP. Echogenic swirling pattern as a predictor of malignant pleural effusions in patients with malignancies. Chest 2004; 126 (01) 129-134
- 86 Leung AN, Müller NL, Miller RR. CT in differential diagnosis of diffuse pleural disease. AJR Am J Roentgenol 1990; 154 (03) 487-492
- 87 Yilmaz U, Polat G, Sahin N, Soy O, Gülay U. CT in differential diagnosis of benign and malignant pleural disease. Monaldi Arch Chest Dis 2005; 63 (01) 17-22
- 88 Traill ZC, Davies RJ, Gleeson FV. Thoracic computed tomography in patients with suspected malignant pleural effusions. Clin Radiol 2001; 56 (03) 193-196
- 89 Duysinx B, Nguyen D, Louis R. , et al. Evaluation of pleural disease with 18-fluorodeoxyglucose positron emission tomography imaging. Chest 2004; 125 (02) 489-493
- 90 Erasmus JJ, McAdams HP, Rossi SE, Goodman PC, Coleman RE, Patz EF. FDG PET of pleural effusions in patients with non-small cell lung cancer. AJR Am J Roentgenol 2000; 175 (01) 245-249
- 91 Schaffler GJ, Wolf G, Schoellnast H. , et al. Non-small cell lung cancer: evaluation of pleural abnormalities on CT scans with 18F FDG PET. Radiology 2004; 231 (03) 858-865
- 92 Toaff JS, Metser U, Gottfried M. , et al. Differentiation between malignant and benign pleural effusion in patients with extra-pleural primary malignancies: assessment with positron emission tomography-computed tomography. Invest Radiol 2005; 40 (04) 204-209
- 93 Benlloch S, Galbis-Caravajal JM, Martín C. , et al. Potential diagnostic value of methylation profile in pleural fluid and serum from cancer patients with pleural effusion. Cancer 2006; 107 (08) 1859-1865
- 94 Garcia LW, Ducatman BS, Wang HH. The value of multiple fluid specimens in the cytological diagnosis of malignancy. Mod Pathol 1994; 7 (06) 665-668
- 95 Nance KV, Shermer RW, Askin FB. Diagnostic efficacy of pleural biopsy as compared with that of pleural fluid examination. Mod Pathol 1991; 4 (03) 320-324
- 96 Ong KC, Indumathi V, Poh WT, Ong YY. The diagnostic yield of pleural fluid cytology in malignant pleural effusions. Singapore Med J 2000; 41 (01) 19-23
- 97 Prakash UB, Reiman HM. Comparison of needle biopsy with cytologic analysis for the evaluation of pleural effusion: analysis of 414 cases. Mayo Clin Proc 1985; 60 (03) 158-164
- 98 Sallach SM, Sallach JA, Vasquez E, Schultz L, Kvale P. Volume of pleural fluid required for diagnosis of pleural malignancy. Chest 2002; 122 (06) 1913-1917
- 99 Woenckhaus M, Grepmeier U, Werner B. , et al. Microsatellite analysis of pleural supernatants could increase sensitivity of pleural fluid cytology. J Mol Diagn 2005; 7 (04) 517-524
- 100 Porcel JM. Biomarkers in the diagnosis of pleural diseases: a 2018 update. Ther Adv Respir Dis 2018; 12: 1-11
- 101 Jakubec P, Kolek V, Václavík A. , et al. Closed pleural biopsy in the diagnostics of malignant pleural involvement [in Czech]. Vnitr Lek 2014; 60 (5–6): 423-430
- 102 Chakrabarti B, Ryland I, Sheard J, Warburton CJ, Earis JE. The role of Abrams percutaneous pleural biopsy in the investigation of exudative pleural effusions. Chest 2006; 129 (06) 1549-1555
- 103 Jiménez D, Pérez-Rodriguez E, Diaz G, Fogue L, Light RW. Determining the optimal number of specimens to obtain with needle biopsy of the pleura. Respir Med 2002; 96 (01) 14-17
- 104 Bhattacharya S, Bairagya TD, Das A, Mandal A, Das SK. Closed pleural biopsy is still useful in the evaluation of malignant pleural effusion. J Lab Physicians 2012; 4 (01) 35-38
- 105 Maskell NA, Gleeson FV, Davies RJ. Standard pleural biopsy versus CT-guided cutting-needle biopsy for diagnosis of malignant disease in pleural effusions: a randomised controlled trial. Lancet 2003; 361 (9366): 1326-1330
- 106 Ernst A, Hersh CP, Herth F. , et al. A novel instrument for the evaluation of the pleural space: an experience in 34 patients. Chest 2002; 122 (05) 1530-1534
- 107 Mathur PN, Astoul P, Boutin C. Medical thoracoscopy. Technical details. Clin Chest Med 1995; 16 (03) 479-486
- 108 Munavvar M, Khan MA, Edwards J, Waqaruddin Z, Mills J. The autoclavable semirigid thoracoscope: the way forward in pleural disease?. Eur Respir J 2007; 29 (03) 571-574
- 109 Tassi GF, Davies RJ, Noppen M. Advanced techniques in medical thoracoscopy. Eur Respir J 2006; 28 (05) 1051-1059