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CC BY-NC-ND 4.0 · Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 2019; 38(04): 336-341
DOI: 10.1055/s-0039-1695016
Case Report | Relato de Caso
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Delayed Cerebral Metastasis of Breast Cancer: Case Report and Molecular Review

Mestástase cerebral tardia de cancêr de mama: Relato de caso e revisão molecular
Leonardo Dessesards Olijnyk 
1   Skull Base Surgery Institute, Hospital Ernesto Dornelles, Porto Alegre, RS, Brazil
,
Artur Nobrega Lima Morais
1   Skull Base Surgery Institute, Hospital Ernesto Dornelles, Porto Alegre, RS, Brazil
,
Rodolfo Figueiredo Carvalho
1   Skull Base Surgery Institute, Hospital Ernesto Dornelles, Porto Alegre, RS, Brazil
,
Adriana Abrão
1   Skull Base Surgery Institute, Hospital Ernesto Dornelles, Porto Alegre, RS, Brazil
,
Krunal Patel
3   Toronto Western Hospital& Krembil Neuroscience Institute, University Health Network & University of Toronto, Toronto, ON, Canada
,
Carlos Eduardo Silva
1   Skull Base Surgery Institute, Hospital Ernesto Dornelles, Porto Alegre, RS, Brazil
2   Human Anatomy Department, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil
› Author Affiliations
Further Information

Publication History

07 March 2019

27 May 2019

Publication Date:
27 August 2019 (online)

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Abstract

Breast cancer (BC) is a prevalent disease, and its incidence of brain metastasis (BM) varies from 5 to 30% according to the literature. We present the case of a delayed isolated cerebral metastasis in a female patient following a period of 16 years after the diagnosis and first treatment. During this time, there was no other recurrence. We also review the literature concerning central nervous system spread and the molecular subtypes of such late tumors.

Resumo

O câncer de mama é uma doença prevalente e sua incidência de metástase cerebral varia de 5 a 30%, de acordo com a literatura. Apresentamos um caso de metástase cerebral tardia isolada em uma paciente do sexo feminino após um período de 16 anos do diagnóstico e tratamento. Durante esse período, não houve outra recorrência. Também é feita uma breve revisão da literatura sobre metástases de câncer de mama no sistema nervoso central e suas características moleculares.

Keywords

breast cancer - neuro-oncology - delayed metastasis

Palavras-chave

câncer de mama - neuro-oncologia - metástase tardia
 

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