J Knee Surg 2021; 34(03): 247-250
DOI: 10.1055/s-0039-1694736
Original Article

Short-Term Outcomes of Synovectomy and Total Knee Replacement in Patients with Diffuse-Type Pigmented Villonodular Synovitis

Weiping Su*
1   Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
,
Yangying Zhou*
2   Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan, China
,
Wei Lu
1   Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
,
Min Zeng
1   Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
,
Yihe Hu
1   Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
,
Jie Xie
1   Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
› Author Affiliations

Abstract

Diffuse-type pigmented villonodular synovitis is a rare benign disease that causes disorders of the knee, including erosion of subchondral bone and cyst formation, with eventual osteoarthritis. The purpose of this study was to evaluate the short-term outcomes of synovectomy and total knee replacement in patients with the diffuse type of pigmented villonodular synovitis. From November 2011 to May 2015, we performed synovectomy and total knee replacement in 28 patients with diffuse pigmented villonodular synovitis diagnosed on the basis of histopathology of biopsy specimens. Clinical data were collected perioperatively and during follow-up for evaluation of surgical efficacy. No intraoperative complications were encountered. Mean operative duration was 73.4 minutes (range: 47–115 minutes); mean estimated blood loss was 223.9 mL (range: 50–600 mL). The mean duration of follow-up was 58.7 months (range: 36–84 months). Mean range of motion improved from 86.1 ± 11.3 degrees (range: 60–100 degrees) to 107 ± 11.4 degrees (range: 90–130 degrees). Average Knee Society clinical scores improved from 38.9 ± 9.5 (range: 17–54) to 84.4 ± 6.1 (range: 75–98); functional scores improved from 48.9 ± 13.1 (range: 25–80) to 84.6 ± 6.1 (range: 75–95; p < 0.05 for both). Postoperative radiographs showed no signs of prosthesis loosening, periprosthetic fractures, or dislocation. The short-term efficacy of synovectomy and total knee replacement in treating patients with diffuse pigmented villonodular synovitis was satisfactory.

* Weiping Su and Yangying Zhou contributed equally to this study.




Publication History

Received: 03 January 2019

Accepted: 03 July 2019

Article published online:
21 August 2019

© 2019. Thieme. All rights reserved.

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