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CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci 2019; 55(01): 014-017
DOI: 10.1055/s-0039-1694081
Review Article
National Academy of Medical Sciences (India)

Nanoceria and Its Biomedical Relevance

Jyotsna Kailashiya
1   Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
,
Debabrata Dash
1   Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
› Institutsangaben
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Publikationsdatum:
02. Oktober 2019 (online)

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Abstract

Nanoceria is a nanosized particle preparation of cerium oxide. It shows mixture of cerium in the 3+ and 4+ states on the nanoparticle surface, giving it interesting redox properties. Nanoceria shows effective biological antioxidant properties, which makes it a great candidate for biomedical applications. Many studies have shown promising results on therapeutic potential of nanoceria in diseases like cancer, diabetes, atherosclerosis, and neurodegenerative diseases. Meanwhile, other studies explored biodistribution and toxicity of nanoceria. This review article describes nanoceria, its relevant biomedical applications, and adverse effects, based on previously reported studies.

Keywords

cerium oxide nanoparticles - antioxidant - reactive oxygen species - inflammatory diseases
 

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