RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000083.xml
Synlett 2020; 31(11): 1027-1032
DOI: 10.1055/s-0039-1690841
DOI: 10.1055/s-0039-1690841
synpacts
Rapid Assembly of Molecular Complexity from Simple Enamides
We are grateful for financial supported by the Research Unit Nanokat at the TU Kaiserslautern, the Deutsche Forschungsgemeinschaft (DFG), the Fonds der Chemischen Industrie (FCI), the Evonik Stiftung, and the Polytechnische Gesellschaft Frankfurt.Weitere Informationen
Publikationsverlauf
Received: 20. Januar 2020
Accepted after revision: 07. Februar 2020
Publikationsdatum:
02. März 2020 (online)
Abstract
The efficient assembly of structurally complex molecules containing multiple continuous stereogenic centers still constitutes a tremendous challenge for any synthetic organic chemist. In this article, we briefly summarize our recent advances in the utilization of enamides as versatile building blocks for the rapid and highly stereoselective construction of different molecular scaffolds containing up to five continuous stereocenters.
-
References
- 1a Whitesides GM, Ismagilov RF. Science 1999; 284: 89
- 1b Nicolaou KC, Hale CR. H, Nilewski C, Ioannidou HA. Chem. Soc. Rev. 2012; 41: 5185
- 1c Nicolaou KC. Chem. Commun. 2003; 661
- 2a Caille S, Cui S, Faul MM, Mennen SM, Tedrow JS, Walker SD. J. Org. Chem. 2019; 84: 4583
- 2b Méndez-Lucio O, Medina-Franco JL. Drug Discovery Today 2017; 22: 120
- 3a Li J, Eastgate MD. Org. Biomol. Chem. 2015; 13: 7164
- 3b Mathematical and computational chemistry . Bonchev DG, Rouvray DH. Springer; New York: 2005
- 4a Eppe G, Didier D, Marek I. Chem. Rev. 2015; 115: 9175
- 4b Pellissier H. Chem. Rev. 2013; 113: 442
- 4c Volla CM. R, Atodiresei I, Rueping M. Chem. Rev. 2014; 114: 2390
- 5a Bernadat G, Masson G. Synlett 2014; 25: 2842
- 5b Carbery DR. Org. Biomol. Chem. 2008; 6: 3455
- 5c Courant T, Dagousset G, Masson G. Synthesis 2015; 47: 1799
- 5d Gigant N, Chausset-Boissarie L, Gillaizeau I. Chemistry 2014; 20: 7548
- 5e Gopalaiah K, Kagan HB. Chem. Rev. 2011; 111: 4599
- 5f Matsubara R, Kobayashi S. Acc. Chem. Res. 2008; 41: 292
- 6 Halli J, Bolte M, Bats J, Manolikakes G. Org. Lett. 2017; 19: 674
- 7 Halli J, Kramer P, Grimmer J, Bolte M, Manolikakes G. J. Org. Chem. 2018; 83: 12007
- 8 Kramer P, Schönfeld J, Bolte M, Manolikakes G. Org. Lett. 2018; 20: 178
- 9 Matsubara R, Nakamura Y, Kobayashi S. Angew. Chem. Int. Ed. 2004; 43: 3258
- 10 Fossey JS, Matsubara R, Vital P, Kobayashi S. Org. Biomol. Chem. 2005; 3: 2910
- 11 Kramer P, Grimmer J, Bolte M, Manolikakes G. Angew. Chem. Int. Ed. 2019; 58: 13056