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Vet Comp Orthop Traumatol 2019; 32(05): 394-400
DOI: 10.1055/s-0039-1688985
Original Research
Georg Thieme Verlag KG Stuttgart · New York

Diagnostic Ultrasound Detection of Changes in Femoral Muscle Mass Recovery after Tibial Plateau Levelling Osteotomy in Dogs

Ilan Frank
1   Department of Clinical Sciences, Veterinary Teaching Hospital, Colorado State University, Fort Collins, Colorado, United States
,
Felix Duerr 
1   Department of Clinical Sciences, Veterinary Teaching Hospital, Colorado State University, Fort Collins, Colorado, United States
,
Brian Zanghi
2   Nestlé Purina Research, St. Louis, Missouri, United States
,
Rondo Middleton
2   Nestlé Purina Research, St. Louis, Missouri, United States
,
Linda Lang
3   Department of Environmental & Radiological Health Sciences, Veterinary Teaching Hospital, Colorado State University, Fort Collins, Colorado, United States
› Author Affiliations Funding Funding for this project was provided by Nestlé Purina PetCare.
Further Information

Publication History

17 October 2018

27 March 2019

Publication Date:
29 May 2019 (online)

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Abstract

Objective The goal of this study was to develop a clinically feasible ultrasound (US) protocol that can detect changes in thigh muscle mass in dogs after stifle surgery. The primary aim of this study was to compare previously described US measurement locations of the canine thigh for detecting changes in muscle mass in dogs recovering from tibial plateau levelling osteotomy (TPLO).

Study Design This was a prospective, exploratory pilot study. Adult dogs (n = 7) undergoing pet-owner elected TPLO were enrolled. Twelve different US measurements were performed in triplicate by a single experienced observer. Measurements were performed at 0, 2, 4 and 8 weeks after surgery at a proximal and distal location along the femur. Data from all available time points and locations were analysed for the main effect of time within modalities.

Results A total of 1,008 US measurements were performed. Measurements of the transverse sectional area of the rectus femoris muscle detected significant (p  ≤  0.05) muscle loss between weeks 0 and 2 at the lateral and medial aspects of the distal location (19% and 15% respectively). Measurements of the thigh muscle thickness were significantly (p < 0.01) increased between 2nd- and 8th- week time points at the lateral aspect of the proximal location (26%).

Conclusion The proximal femoral location, measured from the lateral aspect, appears to be the most suitable US measurement for detecting increases in femoral muscle mass in dogs recovering from TPLO. The provided pilot data suggest that further research evaluating this outcome measure is indicated.

Keywords

thigh circumference - ultrasound - muscle recovery - tibial plateau levelling osteotomy - dogs

Author Contribution

Ilan Frank, Felix Duerr and Linda Lang contributed to the study conception, the study design, the acquisition of data, data analysis and interpretation, drafting or revising of the manuscript, and approved the submitted manuscript. Brian Zanghi and Rondo Middleton contributed to the study conception, the study design, data analysis and interpretation, drafting or revising of the manuscript, and approved the submitted manuscript.


Supplementary Material

 

  • References

  • 1 Aragon CL, Budsberg SC. Applications of evidence-based medicine: cranial cruciate ligament injury repair in the dog. Vet Surg 2005; 34 (02) 93-98
    CrossrefPubMedSearch in Google Scholar
  • 2 Whitehair JG, Vasseur PB, Willits NH. Epidemiology of cranial cruciate ligament rupture in dogs. J Am Vet Med Assoc 1993; 203 (07) 1016-1019
    CrossrefPubMedSearch in Google Scholar
  • 3 Monk ML, Preston CA, McGowan CM. Effects of early intensive postoperative physiotherapy on limb function after tibial plateau leveling osteotomy in dogs with deficiency of the cranial cruciate ligament. Am J Vet Res 2006; 67 (03) 529-536
    CrossrefPubMedSearch in Google Scholar
  • 4 Moeller EM, Allen DA, Wilson ER, Lineberger JA, Lehenbauer T. Long-term outcomes of thigh circumference, stifle range-of-motion, and lameness after unilateral tibial plateau levelling osteotomy. Vet Comp Orthop Traumatol 2010; 23 (01) 37-42
    Thieme ConnectPubMedSearch in Google Scholar
  • 5 Millis DL, Levine D. Assessing and measuring outcomes. In: Canine Rehabilitation and Physical Therapy. 2nd ed. WB Saunders, Philadelphia: Elsevier; 2014: 220-242
    Search in Google Scholar
  • 6 McCarthy DA, Millis DL, Levine D, Weigel JP. Variables affecting thigh girth measurement and observer reliability in dogs. Front Vet Sci 2018; 5: 203
    CrossrefPubMedSearch in Google Scholar
  • 7 Bascuñán AL, Kieves N, Goh C. , et al. Evaluation of factors influencing thigh circumference measurement in dogs. Vet Evid 2016; 1 (02) 12
    PubMedSearch in Google Scholar
  • 8 Smith TJ, Baltzer WI, Jelinski SE, Salinardi BJ. Inter- and intratester reliability of anthropometric assessment of limb circumference in Labrador Retrievers. Vet Surg 2013; 42 (03) 316-321
    CrossrefPubMedSearch in Google Scholar
  • 9 Mostafa AA, Griffon DJ, Thomas MW, Constable PD. Morphometric characteristics of the pelvic limb musculature of Labrador Retrievers with and without cranial cruciate ligament deficiency. Vet Surg 2010; 39 (03) 380-389
    CrossrefPubMedSearch in Google Scholar
  • 10 Francis DA, Millis DL, Head LL. Bone and lean tissue changes following cranial cruciate ligament transection and stifle stabilization. J Am Anim Hosp Assoc 2006; 42 (02) 127-135
    CrossrefPubMedSearch in Google Scholar
  • 11 Ticinesi A, Meschi T, Narici MV, Lauretani F, Maggio M. Muscle ultrasound and sarcopenia in older individuals: a clinical perspective. J Am Med Dir Assoc 2017; 18 (04) 290-300
    CrossrefPubMedSearch in Google Scholar
  • 12 Mourtzakis M, Wischmeyer P. Bedside ultrasound measurement of skeletal muscle. Curr Opin Clin Nutr Metab Care 2014; 17 (05) 389-395
    CrossrefPubMedSearch in Google Scholar
  • 13 Dupont AC, Sauerbrei EE, Fenton PV, Shragge PC, Loeb GE, Richmond FJ. Real-time sonography to estimate muscle thickness: comparison with MRI and CT. J Clin Ultrasound 2001; 29 (04) 230-236
    CrossrefPubMedSearch in Google Scholar
  • 14 Weiss LW, Coney HD, Clark FC. Gross measures of exercise-induced muscular hypertrophy. J Orthop Sports Phys Ther 2000; 30 (03) 143-148
    CrossrefPubMedSearch in Google Scholar
  • 15 Annetta MG, Pittiruti M, Silvestri D. , et al. Ultrasound assessment of rectus femoris and anterior tibialis muscles in young trauma patients. Ann Intensive Care 2017; 7 (01) 104
    CrossrefPubMedSearch in Google Scholar
  • 16 Pretorius A, Keating J. Validity of real time ultrasound for measuring skeletal muscle size. Phys Ther Rev 2008; 13 (06) 415-426
    CrossrefPubMedSearch in Google Scholar
  • 17 Sakaeda K, Shimizu M. Use of B-mode ultrasonography for measuring femoral muscle thickness in dogs. J Vet Med Sci 2016; 78 (05) 803-810
    CrossrefPubMedSearch in Google Scholar
  • 18 Bullen LE, Evola MG, Griffith EH, Seiler GS, Saker KE. Validation of ultrasonographic muscle thickness measurements as compared to the gold standard of computed tomography in dogs. Peer J 2017; 5: e2926
    CrossrefPubMedSearch in Google Scholar
  • 19 Laflamme D. Development and validation of a body condition score system for dogs. Canine Pract 1997; 22: 10-15
    PubMedSearch in Google Scholar
  • 20 Slocum B, Slocum TD. Tibial plateau leveling osteotomy for repair of cranial cruciate ligament rupture in the canine. Vet Clin North Am Small Anim Pract 1993; 23 (04) 777-795
    CrossrefPubMedSearch in Google Scholar
  • 21 Jaegger G, Marcellin-Little DJ, Levine D. Reliability of goniometry in Labrador Retrievers. Am J Vet Res 2002; 63 (07) 979-986
    CrossrefPubMedSearch in Google Scholar
  • 22 Hutchinson D, Sutherland-Smith J, Watson AL, Freeman LM. Assessment of methods of evaluating sarcopenia in old dogs. Am J Vet Res 2012; 73 (11) 1794-1800
    CrossrefPubMedSearch in Google Scholar
  • 23 Kim J, Kazmierczak KA, Breur GJ. Comparison of temporospatial and kinetic variables of walking in small and large dogs on a pressure-sensing walkway. Am J Vet Res 2011; 72 (09) 1171-1177
    CrossrefPubMedSearch in Google Scholar
  • 24 Kano WT, Rahal SC, Agostinho FS. , et al. Kinetic and temporospatial gait parameters in a heterogeneous group of dogs. BMC Vet Res 2016; 12 (01) 2
    CrossrefPubMedSearch in Google Scholar
  • 25 Millis DL, Ciuperca IA. Evidence for canine rehabilitation and physical therapy. Vet Clin North Am Small Anim Pract 2015; 45 (01) 1-27
    CrossrefPubMedSearch in Google Scholar
  • 26 Thomaes T, Thomis M, Onkelinx S, Coudyzer W, Cornelissen V, Vanhees L. Reliability and validity of the ultrasound technique to measure the rectus femoris muscle diameter in older CAD-patients. BMC Med Imaging 2012; 12 (01) 7
    CrossrefPubMedSearch in Google Scholar
  • 27 Berger J, Bunout D, Barrera G. , et al. Rectus femoris (RF) ultrasound for the assessment of muscle mass in older people. Arch Gerontol Geriatr 2015; 61 (01) 33-38
    CrossrefPubMedSearch in Google Scholar
  • 28 Lieber RL, Fridén JO, Hargens AR, Danzig LA, Gershuni DH. Differential response of the dog quadriceps muscle to external skeletal fixation of the knee. Muscle Nerve 1988; 11 (03) 193-201
    CrossrefPubMedSearch in Google Scholar
  • 29 Lieber RL, McKee-Woodburn T, Gershuni DH. Recovery of the dog quadriceps after 10 weeks of immobilization followed by 4 weeks of remobilization. J Orthop Res 1989; 7 (03) 408-412
    CrossrefPubMedSearch in Google Scholar
  • 30 Budsberg SC, Verstraete MC, Soutas-Little RW, Flo GL, Probst CW. Force plate analyses before and after stabilization of canine stifles for cruciate injury. Am J Vet Res 1988; 49 (09) 1522-1524
    PubMedSearch in Google Scholar
  • 31 Jevens DJ, DeCamp CE, Hauptman J, Braden TD, Richter M, Robinson R. Use of force-plate analysis of gait to compare two surgical techniques for treatment of cranial cruciate ligament rupture in dogs. Am J Vet Res 1996; 57 (03) 389-393
    CrossrefPubMedSearch in Google Scholar
  • 32 Matsunaga N, Ito T, Noritake K. , et al. Correlation between the Gait Deviation Index and skeletal muscle mass in children with spastic cerebral palsy. J Phys Ther Sci 2018; 30 (09) 1176-1179
    CrossrefPubMedSearch in Google Scholar
  • 33 Doxey G. Assessing quadriceps femoris muscle bulk with girth measurements in subjects with patellofemoral pain. J Orthop Sports Phys Ther 1987; 9 (05) 177-183
    CrossrefPubMedSearch in Google Scholar
  • 34 Farese JP, Todhunter RJ, Lust G, Williams AJ, Dykes NL. Dorsolateral subluxation of hip joints in dogs measured in a weight-bearing position with radiography and computed tomography. Vet Surg 1998; 27 (05) 393-405
    CrossrefPubMedSearch in Google Scholar
  • 35 Sarwal A, Parry SM, Berry MJ. , et al. Interobserver reliability of quantitative muscle sonographic analysis in the critically ill population. J Ultrasound Med 2015; 34 (07) 1191-1200
    CrossrefPubMedSearch in Google Scholar