CC BY-NC-ND 4.0 · Journal of Academic Ophthalmology 2019; 11(01): e43-e49
DOI: 10.1055/s-0039-1688912
Research Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Assessment of Intravitreal Injection Training among U.S.-Based Ophthalmology Residents

Jacob J. Liechty
1   Pennsylvania State College of Medicine, Hershey, Pennsylvania
,
Michael J. Wilkinson
2   Department of Ophthalmology, Pennsylvania State College of Medicine, Hershey, Pennsylvania
,
Esther M. Bowie
2   Department of Ophthalmology, Pennsylvania State College of Medicine, Hershey, Pennsylvania
› Author Affiliations
Funding None.
Further Information

Publication History

26 August 2018

08 April 2019

Publication Date:
25 May 2019 (online)

Abstract

Purpose To describe the intravitreal injection training of ophthalmology residents in the United States in 2018.

Design Cross-sectional survey.

Methods An anonymous, 29-question, internet-based survey was emailed to 119 ophthalmology residency program directors with the instructions to forward the survey to their ophthalmology residents.

Results A total of 117 ophthalmology residents (7.89%) responded to the survey. The majority of residents stated that their intravitreal injection training began during their first year of ophthalmology training, PGY 2 year, (92.3%). The majority of residents performed at least 25 injections per year (78.6%). All residents use antiseptic on the conjunctiva prior to the injection, 94% use a lid speculum, and 84.6% avoided talking in the procedure room. Most injections are performed with gloves (83.8%). A minority of residents stated that they are trained to use povidone-iodine on the eyelids prior to performing an injection (45.3%). Only 6.0% of residents claimed to use postinjection antibiotic drops. Performance of bilateral, simultaneous intravitreal injections was split with nearly half of residents not being trained in this method (47.9%).

Conclusion Ophthalmology residents from across the country experience a variety of different injection protocols when being trained on how to perform intravitreal injections. Conjunctival antisepsis has reached a clear consensus while topics such as simultaneous, bilateral injections and eyelid antisepsis are still uncertain among the resident community.

 
  • References

  • 1 Ramulu PY, Do DV, Corcoran KJ, Corcoran SL, Robin AL. Use of retinal procedures in medicare beneficiaries from 1997 to 2007. Arch Ophthalmol 2010; 128 (10) 1335-1340
  • 2 Murray TG. 2012 Intravitreal injection techniques: maximizing comfort and minimizing the risk of endophthalmitis. ASRS On-Demand Webinar, September 19, 2012. Available at: http://www.asrs.org/education/calendar/event/51/on-demand-webinar-intravitreal-injection-techniques-maximizing-comfort-and-minim . Accessed April 24, 2019
  • 3 Fintak DR, Shah GK, Blinder KJ. , et al. Incidence of endophthalmitis related to intravitreal injection of bevacizumab and ranibizumab. Retina 2008; 28 (10) 1395-1399
  • 4 Meyer CH, Michels S, Rodrigues EB. , et al. Incidence of rhegmatogenous retinal detachments after intravitreal antivascular endothelial factor injections. Acta Ophthalmol 2011; 89 (01) 70-75
  • 5 Arevalo JF, Maia M, Flynn Jr HW. , et al. Tractional retinal detachment following intravitreal bevacizumab (Avastin) in patients with severe proliferative diabetic retinopathy. Br J Ophthalmol 2008; 92 (02) 213-216
  • 6 Hoang QV, Mendonca LS, Della Torre KE, Jung JJ, Tsuang AJ, Freund KB. Effect on intraocular pressure in patients receiving unilateral intravitreal anti-vascular endothelial growth factor injections. Ophthalmology 2012; 119 (02) 321-326
  • 7 Poku E, Rathbone J, Wong R. , et al. The safety of intravitreal bevacizumab monotherapy in adult ophthalmic conditions: systematic review. BMJ Open 2014; 4 (07) e005244
  • 8 Scott IU, Smalley AD, Kunselman AR. Ophthalmology residency program leadership expectations of resident competency in retinal procedures and resident experience with retinal procedures. Retina 2009; 29 (02) 251-256
  • 9 Green-Simms AE, Ekdawi NS, Bakri SJ. Survey of intravitreal injection techniques among retinal specialists in the United States. Am J Ophthalmol 2011; 151 (02) 329-332
  • 10 Xing L, Dorrepaal SJ, Gale J. Survey of intravitreal injection techniques and treatment protocols among retina specialists in Canada. Can J Ophthalmol 2014; 49 (03) 261-266
  • 11 Anijeet DR, Hanson RJ, Bhagey J, Bates RA. National survey of the technique of intravitreal triamcinolone injection in the United Kingdom. Eye (Lond) 2007; 21 (04) 480-486
  • 12 Segal O, Segal-Trivitz Y, Nemet AY, Geffen N, Nesher R, Mimouni M. Survey of intravitreal injection techniques among retina specialists in Israel. Clin Ophthalmol 2016; 10: 1111-1116
  • 13 Avery RL, Bakri SJ, Blumenkranz MS. , et al. Intravitreal injection technique and monitoring: updated guidelines of an expert panel. Retina 2014; 34 (Suppl. 12) S1-S18
  • 14 American Academy of Ophthalmology. Intravitreal injections – 2015. Available at: https://www.aao.org/clinical-statement/intravitreal-injections-statement . Accessed November 28, 2018
  • 15 Bhavsar AR, Googe Jr JM, Stockdale CR. , et al; Diabetic Retinopathy Clinical Research Network. Risk of endophthalmitis after intravitreal drug injection when topical antibiotics are not required: the diabetic retinopathy clinical research network laser-ranibizumab-triamcinolone clinical trials. Arch Ophthalmol 2009; 127 (12) 1581-1583
  • 16 Cheung CS, Wong AW, Lui A, Kertes PJ, Devenyi RG, Lam WC. Incidence of endophthalmitis and use of antibiotic prophylaxis after intravitreal injections. Ophthalmology 2012; 119 (08) 1609-1614
  • 17 McCannel CA. Meta-analysis of endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents: causative organisms and possible prevention strategies. Retina 2011; 31 (04) 654-661
  • 18 Chen E, Lin MY, Cox J, Brown DM. Endophthalmitis after intravitreal injection: the importance of viridans streptococci. Retina 2011; 31 (08) 1525-1533
  • 19 Wen JC, McCannel CA, Mochon AB, Garner OB. Bacterial dispersal associated with speech in the setting of intravitreous injections. Arch Ophthalmol 2011; 129 (12) 1551-1554
  • 20 Pilli S, Kotsolis A, Spaide RF. , et al. Endophthalmitis associated with intravitreal anti-vascular endothelial growth factor therapy injections in an office setting. Am J Ophthalmol 2008; 145 (05) 879-882
  • 21 Bhavsar AR, Stockdale CR, Ferris III FL, Brucker AJ, Bressler NM, Glassman AR. ; Diabetic Retinopathy Clinical Research Network. Update on risk of endophthalmitis after intravitreal drug injections and potential impact of elimination of topical antibiotics. Arch Ophthalmol 2012; 130 (06) 809-810
  • 22 Storey P, Dollin M, Pitcher J. , et al; Post-Injection Endophthalmitis Study Team. The role of topical antibiotic prophylaxis to prevent endophthalmitis after intravitreal injection. Ophthalmology 2014; 121 (01) 283-289
  • 23 Bhatt SS, Stepien KE, Joshi K. Prophylactic antibiotic use after intravitreal injection: effect on endophthalmitis rate. Retina 2011; 31 (10) 2032-2036
  • 24 Kim SJ, Toma HS. Antimicrobial resistance and ophthalmic antibiotics: 1-year results of a longitudinal controlled study of patients undergoing intravitreal injections. Arch Ophthalmol 2011; 129 (09) 1180-1188
  • 25 Dave SB, Toma HS, Kim SJ. Ophthalmic antibiotic use and multidrug-resistant staphylococcus epidermidis: a controlled, longitudinal study. Ophthalmology 2011; 118 (10) 2035-2040
  • 26 Aiello LP, Brucker AJ, Chang S. , et al. Evolving guidelines for intravitreous injections. Retina 2004; 24 (5, Suppl): S3-S19
  • 27 Willekens K, Reyns G, Diricx M. , et al. Intravitreally injected fluid dispersion: importance of injection technique. Invest Ophthalmol Vis Sci 2017; 58 (03) 1434-1441
  • 28 Chao DL, Gregori NZ, Khandji J, Goldhardt R. Safety of bilateral intravitreal injections delivered in a teaching institution. Expert Opin Drug Deliv 2014; 11 (07) 991-993