Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000169.xml
CC BY-NC-ND 4.0 · AJP Rep 2019; 09(02): e147-e152
DOI: 10.1055/s-0039-1687873
DOI: 10.1055/s-0039-1687873
Review Article
Babesiosis in Pregnancy: An Imitator of HELLP Syndrome
Further Information
Publication History
29 November 2018
11 December 2018
Publication Date:
29 April 2019 (online)
Abstract
HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) is a serious pregnancy complication that can cause significant maternal and neonatal morbidity and mortality. There are several conditions that may occur in pregnancy that may imitate the laboratory findings and clinical presentation of HELLP syndrome. Babesiosis is a parasitic imitator of HELLP syndrome that can be spread by the tick, transfusions, or congenitally. Recognition and treatment of this condition is important to optimize maternal and fetal outcomes.
-
References
- 1 Krause PJ, Edoard G, Vannier P. . (2018) Babesiosis: microbiology, epidemiology, and pathogenesis. Available from: https://www.uptodate.com/contents/babesiosis-microbiology-epidemiology-and-pathogenesis . Accessed January 8, 2018
- 2 Babesiosis. (2018) Available from: https://www.cdc.gov/parasites/babesiosis/ . Accessed August 1, 2018
- 3 Vannier E, Krause PJ. Human Babesiosis. N Engl J Med 2012; 366 (25) 2397-2407
- 4 Luckett R, Rodriguez W, Katz D. Babesiosis in pregnancy. Obstet Gynecol 2014; 124 (2 Pt 2, Suppl 1): 419-422
- 5 Gulersen M, Brost BC, Bobrovnikov V, Bornstein E. Acute babesiosis in pregnancy: a novel imitator of hemolysis, elevated liver enzymes, and low platelet count syndrome. Obstet Gynecol 2016; 128 (01) 197-200
- 6 Linden JV, Prusinski MA, Crowder LA. , et al. Transfusion-transmitted and community-acquired babesiosis in New York, 2004 to 2015. Transfusion 2018; 58 (03) 660-668
- 7 Kjemtrup AM, Conrad PA. Human babesiosis: an emerging tick-borne disease. Int J Parasitol 2000; 30 (12,13): 1323-1337
- 8 FDA. U.S. (2018) FDA approves first tests to screen for tickborne parasite in whole blood and plasma to protect the U.S. blood supply. Available from: https://www.fda.gov/newsevents/newsroom/pressannouncements/ucm599782.htm . Accessed August 17, 2018
- 9 Esernio-Jenssen D, Scimeca PG, Benach JL, Tenenbaum MJ. Transplacental/perinatal babesiosis. J Pediatr 1987; 110 (04) 570-572
- 10 Joseph JT, Purtill K, Wong SJ. et al. Vertical transmission of Babesia microti, United States. Emerg Infect Dis 2012; 18 (18) 1318-1321
- 11 Vannier EG, Diuk-Wasser MA, Ben Mamoun C, Krause PJ. Babesiosis. Infect Dis Clin North Am 2015; 29 (02) 357-370
- 12 Spaete J, Patrozou E, Rich JD, Sweeney JD. Red cell exchange transfusion for babesiosis in Rhode Island. J Clin Apher 2009; 24 (03) 97-105
- 13 Feder Jr. HM, Lawlor M, Krause PJ. Babesiosis in pregnancy. N Engl J Med 2003; 349 (02) 195-196
- 14 Hatcher JC, Greenberg PD, Antique J, Jimenez-Lucho VE. Severe babesiosis in Long Island: review of 34 cases and their complications. Clin Infect Dis 2001; 32 (08) 1117-1125
- 15 Sanchez E, Vannier E, Wormser GP, Hu LT. Diagnosis, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: a review. JAMA 2016; 315 (16) 1767-1777
- 16 The American College of Obstetricians and Gynecologists. Hypertension in Pregnancy. Washington, WA: The American College of Obstetricians and Gynecologists; 2013
- 17 Mupombwa T, Mulla BM, Kirby JO'Brien BM. Babesia microti infection in pregnancy mimicking HELLP syndrome. J Bacteriol Parasitol 2016; 7 (06) 1000297-1000298
- 18 Evenson DA, Perry E, Kloster B, Hurley R, Stroncek DF. Therapeutic apheresis for babesiosis. J Clin Apher 1998; 13 (01) 32-36
- 19 Wormser GP, Dattwyler RJ, Shapiro ED. , et al. The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 2006; 43 (09) 1089-1134