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Clin Colon Rectal Surg 2019; 32(04): 280-290
DOI: 10.1055/s-0039-1683917
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Is There a Role for Ileal Pouch Anal Anastomosis in Crohn's Disease?

Nicole E. Lopez
1   Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California
,
Karen Zaghyian
1   Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California
,
Phillip Fleshner
1   Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California
› Author Affiliations
Further Information

Publication History

Publication Date:
17 June 2019 (online)

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Abstract

Traditionally, surgical interventions for colonic Crohn's disease (CD) have been limited to total abdominal colectomy and ileorectal anastomosis, or total proctocolectomy with end ileostomy if there is rectal involvement. However, improved understandings of the biology of CD, as well as the development of biologic therapies, have enabled more limited resections. Here, we review the indications for, and limitations of, specific procedures aiming to preserve intestinal continuity in colonic CD.

Keywords

Crohn's disease - indeterminate colitis - ileal pouch anal anastomosis - de novo Crohn's disease - ileorectal anastomosis
 

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