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CC BY 4.0 · Rev Bras Ginecol Obstet 2019; 41(03): 203-205
DOI: 10.1055/s-0039-1678589
Case Report
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Autoimmune Progesterone Dermatitis: A Case Report

Özhan Özdemir 
1   Department of Obstetrics and Gynecology, Ankara Numune Education and Research Hospital, Ankara, Turkey
,
Gözde Girgin Yahşi
1   Department of Obstetrics and Gynecology, Ankara Numune Education and Research Hospital, Ankara, Turkey
,
Cemal Reşat Atalay
1   Department of Obstetrics and Gynecology, Ankara Numune Education and Research Hospital, Ankara, Turkey
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Publikationsverlauf

29. September 2018

08. Januar 2019

Publikationsdatum:
02. April 2019 (online)

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Abstract

Introduction Autoimmune progesterone dermatitis (APD) is a rare autoimmune dermatosis characterized by recurrent cutaneous and mucosal lesions during the luteal phase of the menstrual cycle that disappear some days after the menses.

Case Report A 34-year-old primipara woman with no significant past medical history and no prior exogenous hormone use, who presented with cyclic skin eruptions starting 1 year after the delivery. The lesions occurred ∼ 6 days before the menses and disappeared in between 1 and 2 days after the menstruation ceased. The patient was diagnosed after a positive response to an intradermal test with progesterone and was successfully treated with combined oral contraceptives. The skin eruptions have not returned since the initiation of this therapy.

Conclusion Dermatologists, gynecologists, and obstetricians should be aware of this rare entity. Furthermore, if this condition is suspected, a thorough history taking on the menstrual cycle and results of the intradermal progesterone test are mandatory.

Keywords

autoimmune - dermatitis - progesterone
 

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