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J Pediatr Genet 2019; 08(01): 027-032
DOI: 10.1055/s-0038-1669445
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Failure to Thrive: An Expanded Differential Diagnosis

Alexandra Lazzara
1   Department of Pediatrics, Penn State Health Children's Hospital, Hershey, Pennsylvania, United States
2   Department of Pediatrics, Johns Hopkins Children's Center, Baltimore, Maryland, United States
,
Carrie Daymont
1   Department of Pediatrics, Penn State Health Children's Hospital, Hershey, Pennsylvania, United States
,
Roger Ladda
1   Department of Pediatrics, Penn State Health Children's Hospital, Hershey, Pennsylvania, United States
,
Jordan Lull
1   Department of Pediatrics, Penn State Health Children's Hospital, Hershey, Pennsylvania, United States
,
Can Ficicioglu
3   Division of Human Genetics, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
,
Jennifer L. Cohen
3   Division of Human Genetics, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
,
Justen Aprile
1   Department of Pediatrics, Penn State Health Children's Hospital, Hershey, Pennsylvania, United States
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Publikationsverlauf

09. Juni 2018

23. Juli 2018

Publikationsdatum:
31. August 2018 (online)

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Abstract

The patient is a term 6-month-old male, who presented with failure to thrive since birth. History was remarkable for suspected milk and soy protein allergy, gastroesophageal reflux, constipation, and abdominal distension that was present since birth. He was losing weight despite oral intake of over 100 kcal/kg per day. Prior workup including laboratory studies, abdominal X-ray, upper gastrointestinal series with fluoroscopy, barium enema, and abdominal ultrasound were all within normal limits. The patient's history, diagnostic evaluation, and final diagnosis are revealed. This case highlights a rare condition presenting as failure to thrive, a common problem with a wide differential diagnosis.

Keywords

Wolman's disease - failure to thrive
 

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