Functional Activities and Concentrations of Plasmin Inhibitors in Normal Subjects and D. I. C. Patients

Summary

Alpha-2-macroglobulin and fast antiplasmin, the main inhibitors of the fibrinolytic system, and the presence of plasmin-antiplasmin complex (P-AP) were studied in 15 DIC patients and in 20 healthy individuals. There was a lack of correlation between immunological and chromogenic substrates alpha-2 antiplasmin levels when P-AP complex were found in DIC patients (in 6/15 cases). The levels of alpha-2-macroglobulin were within the normal range in most of these patients, confirm the secondary role of this inhibitor in fibrinolysis.

Key words

D. I. C. - Fast antiplasmin - Alpha-2-macroglobulin - Plasmin-antiplasmin complex

• References

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