Download PDF
Thromb Haemost 1995; 73(04): 734-735
DOI: 10.1055/s-0038-1653856
Letters to the Editor
Schattauer GmbH Stuttgart

Evaluation of APC Resistance in the Plasma of Patients with Q506 Mutation of Factor V (Factor V Leiden) and Treated by Oral Anticoagulants

Y Cadroy
1   Laboratoire d’Hématologie, Hôpital Purpan, Toulouse, France
,
P Sié
1   Laboratoire d’Hématologie, Hôpital Purpan, Toulouse, France
,
M Alhenc-Gelas
2   Laboratoire d’Hémostase, Hôpital Broussais, Paris, France
,
M Aiach
2   Laboratoire d’Hémostase, Hôpital Broussais, Paris, France
› Author Affiliations
Further Information

Publication History

Received 17 November 1994

Accepted after revision 04 January 1995

Publication Date:
09 July 2018 (online)

Also available at
  PDF Download  Permissions and Reprints
 

  • References

  • 1 Svensson PJ, Dahlbäck B. Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 1994; 330: 517-522
    CrossrefPubMedGoogle Scholar
  • 2 Dahlbäck B, Hildebrand B. Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V. Proc Natl Acad Sci USA 1994; 91: 1396-1400
    CrossrefPubMedGoogle Scholar
  • 3 Griffin JH, Evatt B, Wideman C, Fernandez JA. Anticoagulant protein C pathway defective in majority of thrombophilie patients. Blood 1993; 82: 1989-1993
    PubMedGoogle Scholar
  • 4 Koster T, Rosendaal FR, de RondeH, Briët E, Vandenbroucke JP, Bertina RM. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 1993; 342: 1503-1506
    CrossrefPubMedGoogle Scholar
  • 5 Cadroy Y, Sié P, Boneu B. Frequency of a defective response to activated protein C in patients with a history of venous thrombosis. Blood 1994; 83: 2008-2009
    PubMedGoogle Scholar
  • 6 Lindblad B, Svensson PJ, Dahlbäck B. Arterial and venous thromboembolism with fatal outcome and resistance to activated protein C. Lancet 1994; 343: 917
    CrossrefPubMedGoogle Scholar
  • 7 Halbmayer WM, Haushofer A, Schön R, Fischer M. The prevalence of poor anticoagulant response to activated protein C among patients suffering from stroke or venous thrombosis and among healthy subjects. Blood Coag Fibrinol 1994; 5: 51-57
    CrossrefPubMedGoogle Scholar
  • 8 Cushman M, Bhushan F, Bovill E, Tracy R. Plasma resistance to activated protein C in venous and arterial thrombosis. Thromb Haemostas 1994; 72: 643-651
    PubMedGoogle Scholar
  • 9 Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, De RondeH, Van DerVelden, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67
    CrossrefPubMedGoogle Scholar
  • 10 Sun W, Evatt B, Griffin JH. Blood coagulation factor Va abnormality associated with resistance to activated protein C in venous thrombophilia. Blood 1994; 83: 3120-3125
    PubMedGoogle Scholar
  • 11 Gandrille S, Goosens M, Aiach M. A scanning method to establish the molecular basis of protein C deficiency. Human Mutation 1994; 4: 20-30
    CrossrefPubMedGoogle Scholar