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Thromb Haemost 1977; 37(01): 081-085
DOI: 10.1055/s-0038-1649204
DOI: 10.1055/s-0038-1649204
Original Article
Kinetic Aspects of the Interaction of Blood Clotting Enzymes
VII. The Relation between Clotting Time and Prothrombin ConcentrationFurther Information
Publication History
Received 12 February 1976
Accepted 20 August 1976
Publication Date:
03 July 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00035024/197701/lookinside/thumbnails/10-1055-s-0038-1649204-1.jpg)
Summary
The relation between clotting time and the inverse of prothrombin concentration is shown to be rectilinear.
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References
- 1 Hemker H.G, Hemker P.W, Loeliger E.A. Kinetic aspects of the interaction of blood clotting enzymes. I. Derivation of basic formulas. Thrombosis et Diathesis Haemorrhagica 1965; 13: 155
- 2 Hemker H.C, Muller A.D. Kinetic aspects of the interaction of blood clotting enzymes. V. One-stage estimations in the extrinsic coagulation system. Thrombosis et Diathesis Haemorrhagica 1968; 19: 368
- 3 Hemker H.C, Swart A.C.W, Alink A.M.J. Artifícal reagents for factor VII and X, a computer program for obtaining reference tables for one-stage determinations in the extrinsic system. Thrombosis et Diathesis Haemorrhagica 1972; 27: 205
- 4 Owen W.G, Esmon G.T, Jackson W.M. The conversion of prothrombin to thrombin. I. Characterization of the reaction products formed during the activation of bovine prothrombin. Journal of Biological Chemistry 1974; 249: 594
- 5 Vermeer C, Soute B.A.M, Hemker H.C. A new method for the preparation of artificial factor II reagents from normal human and bovine plasma. Submitted for publication 1976