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Thromb Haemost 1994; 72(04): 648
DOI: 10.1055/s-0038-1648932
Letter to the Editor
Schattauer GmbH Stuttgart

Another Protein S Functional Assay Is Sensitive to Resistance to Activated Protein C

E M Faioni
1   Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, I.R.C.C.S. Maggiore Hospital and University of Milano, Milano, Italy
,
F Boyer-Neumann
2   Service d’Hématologie Biologique, Hopital Antoine-Beclere, Paris, France
,
F Franchi
1   Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, I.R.C.C.S. Maggiore Hospital and University of Milano, Milano, Italy
,
M Wolf
2   Service d’Hématologie Biologique, Hopital Antoine-Beclere, Paris, France
,
D Meyer
2   Service d’Hématologie Biologique, Hopital Antoine-Beclere, Paris, France
,
P M Mannucci
1   Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, I.R.C.C.S. Maggiore Hospital and University of Milano, Milano, Italy
› Author Affiliations
Further Information

Publication History

Received 26 April 1994

Accepted after revision 29 June 1994

Publication Date:
06 July 2018 (online)

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  • References

  • 1 Dahlbäck B, Carlsson M, Svensson PJ. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad USA 1993; 90: 1004-1008
    CrossrefPubMedSearch in Google Scholar
  • 2 Faioni EM, Franchi F, Asti D, Sacchi E, Bemardi F, Mannucci PM. Resistance to activated protein C in nine thrombophilic families: interference in a protein S functional assay. Thromb Haemost 1993; 70: 1067-1071
    Thieme ConnectPubMedSearch in Google Scholar
  • 3 Wolf M, Boyer-Neumann C, Martinoli J-L, Leroy-Matheron C, Amiral J, Meyer D, Larrieu M-J. A new functional assay for human protein S activity using activated factor V as substrate. Thromb Haemost 1989; 62: 1144-1145
    Thieme ConnectPubMedSearch in Google Scholar
  • 4 Preda L, Tripodi A, Valsecchi C, Lombardi A, Finotto E, Mannucci PM. A prothrombin time-based functional assay of protein S. Thromb Res 1990; 60: 19-32
    CrossrefPubMedSearch in Google Scholar
  • 5 Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67
    CrossrefPubMedSearch in Google Scholar