PDF herunterladen
Thromb Haemost 1992; 67(05): 519-520
DOI: 10.1055/s-0038-1648485
Original Articles
Schattauer GmbH Stuttgart

Venous Thrombosis during Pregnancy: Leg and Trimester of Presentation

J S Ginsberg
1   The Department of Medicine and Obstetrics, McMaster University, Italy
,
P Brill-Edwards
1   The Department of Medicine and Obstetrics, McMaster University, Italy
,
R F Burrows
1   The Department of Medicine and Obstetrics, McMaster University, Italy
,
R Bona
2   The Department of Medicine, University of Connecticut, Italy
,
P Prandoni
3   2nd Institute of Internal Medicine, University Hospital of Padua, Italy
,
H R Büller
4   The Centre for Thrombosis, Haemostasis, Atherosclerosis and Inflammation Research, Academic Medical Centre, University of Amsterdam, The Netherlands
,
A Lensing
4   The Centre for Thrombosis, Haemostasis, Atherosclerosis and Inflammation Research, Academic Medical Centre, University of Amsterdam, The Netherlands
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 21. Oktober 1991

Accepted after revision 16. Dezember 1991

Publikationsdatum:
03. Juli 2018 (online)

Auch verfügbar auf
  als PDF herunterladen  Lizenzen und Reprints

Summary

In order to determine the relative frequencies of left and right leg venous thrombosis during pregnancy and the frequencies of venous thrombosis during the three trimesters, a cohort study of 60 consecutive patients with a first episode of venous thrombosis during pregnancy was performed. Fifty-eight women had isolated left leg thrombosis, two patients had bilateral venous thrombosis and no patient had isolated right leg venous thrombosis. Thirteen patients had venous thrombosis during the first trimester (21.7%), 28 during the second trimester (46.7%) and 19 during the third trimester (31.7%). These findings indicate that patients with symptoms in the right leg rarely have venous thrombosis. Because leg pain and swelling occur most frequently during the third trimester but venous thrombosis is relatively equally distributed during all three trimesters, patients presenting earlier during pregnancy are more likely to have venous thrombosis than patients presenting later during pregnancy.

 

  • References

  • 1 Kaunitz AM, Hughes JM, Grimes DA, Smith JC, Rochat RW, Kafrissen ME. Causes of maternal mortality in the United States. Obstet Gynecol 1985; 65: 605-612
    PubMedSuche in Google Scholar
  • 2 Ginsberg JS, Turner C, Brill-Edwards P, Harrison L, Hirsh J. Pseudothrombosis in pregnancy. CMAJ 1988; 1399: 409-410
    PubMedSuche in Google Scholar
  • 3 Ginsberg JS, Hirsh J, Rainbow AJ, Coates G. Risks to the fetus of radiologic procedures used in the diagnosis of maternal venous thromboembolic disease. Thromb Haemostas 1989; 61: 189-196
    PubMedSuche in Google Scholar
  • 4 Hull RD, Raskob GE, Carter CJ. Serial impedance plethysmography in pregnant patients with clinically suspected deep vein thrombosis. Ann Intern Med 1990; 112: 663-667
    CrossrefPubMedSuche in Google Scholar
  • 5 Ginsberg JS, Hirsh J. Use of anticoagulants during pregnancy. Chest 1989; 95: 156S-60S
    CrossrefPubMedSuche in Google Scholar
  • 6 Lensing AWA, Prandoni P, Brandjes D, Huisman PM, Vigo M, Tomasella G, Krekt J, ten Cate JW, Huisman MV, Biiller HR. Detection of deep-vein thrombosis by real-time B-mode ultrasonography. N Engl J Med 1989; 320: 342-345
    CrossrefPubMedSuche in Google Scholar
  • 7 Cockett FB, Thomas ML, Negus D. Iliac vein compression. Its relation to iliofemoral thrombosis and the post-thrombotic syndrome. Br Med J 1967; 2: 14-19
    CrossrefPubMedSuche in Google Scholar
  • 8 Andrew M, Mitchell L, Paes B, Berry L, Burrows R, Khambalia B, Ofosu F. A circulating anticoagulant in normal pregnancy. Blood 1989; 74: 97 A
    PubMedSuche in Google Scholar