Thromb Haemost 1992; 67(01): 004-007
DOI: 10.1055/s-0038-1648129
Original Articles
Schattauer GmbH Stuttgart

Deep Vein Thrombosis in Obstetric Patients: Diagnosis and Risk Factors

Karin de Boer
1   The Centre of Haemostasis, Thrombosis, Atherosclerosis and Inflammation Research, Amsterdam, The Netherlands
2   The Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands
,
Harry R Büller
1   The Centre of Haemostasis, Thrombosis, Atherosclerosis and Inflammation Research, Amsterdam, The Netherlands
,
Jan W ten Cate
1   The Centre of Haemostasis, Thrombosis, Atherosclerosis and Inflammation Research, Amsterdam, The Netherlands
,
Marcel Levi
1   The Centre of Haemostasis, Thrombosis, Atherosclerosis and Inflammation Research, Amsterdam, The Netherlands
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 10. April 1991

Accepted after revision 10. Juli 1991

Publikationsdatum:
02. Juli 2018 (online)

Summary

This study was performed to assess the prevalence of deep vein thrombosis (DVT) in consecutive obstetric patients with clinical symptoms of DVT, using impedance plethysmography (IPG) as the diagnostic method and to establish the safety of withholding anticoagulant therapy in patients with a repeatedly normal IPG. In addition, in patients with DVT the prevalence of coagulation and fibrinolytic disorders, which may explain the occurrence of venous thrombosis was investigated.Of the 77 obstetric patients with symptoms of DVT 32 (42%) had an abnormal IPG. The remaining 45 patients had a repeatedly normal IPG and showed no venous thromboembolism during a 6 months follow-up period. Twenty percent (six patients) of the patients with an abnormal IPG had a coagulation or fibrinolytic abnormality. These observations suggest that serial IPG can be used effectively in the management of obstetric patients with clinically suspected DVT and that hemostatic abnormalities are frequently found in those patients with DVT

 
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