The Decreased Circulating Platelet Mass and Its Relation to Bleeding Time in Chronic Renal Failure

E Michalak; B Walkowiak; M Paradowski; C S Cierniewski

doi:10.1055/s-0038-1647445

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Thromb Haemost 1991; 65(01): 011-014
DOI: 10.1055/s-0038-1647445

Original Article

Schattauer GmbH Stuttgart

The Decreased Circulating Platelet Mass and Its Relation to Bleeding Time in Chronic Renal Failure

E Michalak

^*The Department of Nephrology, Military Medical School, Lodz, Poland

,

B Walkowiak

^**The Department of Biophysics, Military Medical School, Lodz, Poland

,

M Paradowski

^***The Department of Medical School, Laboratory Unit, Military Medical School, Lodz, Poland

,

C S Cierniewski

^**The Department of Biophysics, Military Medical School, Lodz, Poland

› Author Affiliations

Further Information

Publication History

Received 06 October 1989

Accepted after revision 21 August 1990

Publication Date:
02 July 2018 (online)

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Abstract
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Summary

The mean platelet volume, measured optically and by the electrical impedance method, was analysed in the patients with chronic renal failure. All parameters describing the circulating platelet biomass except the platelet volume heterogeneity were decreased in these patients. There is a strong inverse relation between the Ivy bleeding time and the platelet mass in the patient group.

Our results indicate that the smaller platelets circulating in the patients with chronic renal failure may contribute to the uremic bleeding diathesis, and disturbed thrombocytopoiesis occurs in chronic renal failure.

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The Decreased Circulating Platelet Mass and Its Relation to Bleeding Time in Chronic Renal Failure

Publication History

Summary

References