Thromb Haemost 1988; 60(02): 343
DOI: 10.1055/s-0038-1647059
Letter to the Editor
Schattauer GmbH Stuttgart

Autoimmune Factor VIII Inhibitor Responsive to Gammaglobulin without In Vitro Neutralisation

Luis O Carreras
1   Department of Haematology, Hospital de Clinicas, University of Buenos Aires and Department of Clinical Biochemistry, Hospital de Clinicas* University of Buenos Aires, Argentina
,
Graciela N Perez
1   Department of Haematology, Hospital de Clinicas, University of Buenos Aires and Department of Clinical Biochemistry, Hospital de Clinicas* University of Buenos Aires, Argentina
,
David L Xavier
1   Department of Haematology, Hospital de Clinicas, University of Buenos Aires and Department of Clinical Biochemistry, Hospital de Clinicas* University of Buenos Aires, Argentina
,
Alicia N Blanco
1   Department of Haematology, Hospital de Clinicas, University of Buenos Aires and Department of Clinical Biochemistry, Hospital de Clinicas* University of Buenos Aires, Argentina
,
Leticia B Penalva
1   Department of Haematology, Hospital de Clinicas, University of Buenos Aires and Department of Clinical Biochemistry, Hospital de Clinicas* University of Buenos Aires, Argentina
› Author Affiliations
Further Information

Publication History

Received 09 February 1988

Accepted after revision 10 May 1988

Publication Date:
28 June 2018 (online)

 
  • References

  • 1 Sultan Y, Kazatchkine MD, Maisonneuve P, Nvdegger JE. Antiidiotvpic suppression of autoantibodies to factor VIII (antihaemophilic factor) bv high-dosc intravenous gammaglobulin. Lancet 1984: 765-768
  • 2 Hiller E, Holler E, Geursen RG, Riess H. Successful treatment with high dose intravenous immunoglobulin in a patient with spontaneous inhibitor to Factor VIII. Blut 1986; 52: 123-126
  • 3 Zimmerman R, Kommerell B, Harenberg J, Eich W, Rothcr K, Schimpf RI. Intravenous IgG for patients with spontaneous inhibitor to factor VIII. Lancet 1985; 273-274
  • 4 Green D, Kwaan HC. (Abstr) An acquired Factor VIII inhibitor responsive to high dose gammaglobulin. Thromb Haemostas 1987; 58: 521
  • 5 Kasper CK, Aiedort LM, Counts RB, Edson JR, Fratantoni J, Green D, Hampton JW, Hilgartner MW, Lazerson J, Levine PH, McMillan CW, Pool JG, Shapiro SS, Shulman NR, Van Evsj. A more uniform measurement of Factor VIII Inhibitors. Thromb Diath Haemorrh 1975; 34: 869-872
  • 6 Rossi F, Sultan Y, Kazatchkine MD. (Abstr) Auto and alloanti-Factor VIII :C antibodies are recognized by anti-idiotypic antibodies contained in normal immunoglobulins. Thromb Haemostas 1987; 58: 521
  • 7 Sultan Y, Rossi F, Kazatchkine MD. Recovery from anti-VIII :C (antihaemophilic factor) autoimmune disease is dependent on generation of anti-idiotypes against anti-VIII ;C autoantibodies. Proc Natl Acad Sci USA 1987; 84: 828-831
  • 8 Moffat EH, Furlong RA, Bloom AL, Peake IR. (Abstr) Antiidiotype reagents in haemophilia In vitro studies. Thromb Haemostas 1987; 58: 520