PDF herunterladen
Thromb Haemost 1991; 66(01): 153-159
DOI: 10.1055/s-0038-1646384
Review Article
Schattauer GmbH Stuttgart

Pathophysiology of Vitamin K-deficiency and Oral Anticoagulants

Cees Vermeer
,
Karly Hamulyák
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
25. Juli 2018 (online)

Auch verfügbar auf
  als PDF herunterladen  Lizenzen und Reprints
 

  • References

  • 1 Wold F. Posttranslational protein modifications: perspectives and prospectives. In: Posttranslational covalent modifications of proteins. ( Johnson BC. ed) Acad Press, New York: 1983. pp 1-17
    Google Scholar
  • 2 Furie B, Furie B C. The molecular basis of blood coagulation. Cell 1988; 53: 505-518
    CrossrefPubMedGoogle Scholar
  • 3 Ulrich M M W, Furie B, Jacobs M R, Vermeer C, Furie B C. Vitamin K-dependent carboxylation: a synthetic peptide based upon the gamma-carboxylation recognition site sequence of the prothrombin propeptide is an active substrate for the carboxylase in vitro. J Biol Chem 1899; 263: 9697-9702
    PubMedGoogle Scholar
  • 4 Olson R E. The function and metabolism of vitamin K. Annu Rev Nutr 1984; 4: 281-337
    CrossrefPubMedGoogle Scholar
  • 5 De Boer-van den Berg M A G, Uitendaal M P, Vermeer C. Direct measurement of vitamin K-dependent enzymes in various isolated and cultured tumor and non-tumor cells. Mol Cell Biochem 1987; 5: 71-76
    PubMedGoogle Scholar
  • 6 Vermeer C. Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase. Biochem J 1990; 266: 625-636
    CrossrefPubMedGoogle Scholar
  • 7 Wu S M, Morris D P, Stafford D W. Identification and purification to near homogeneity of the vitamin K-dependent carboxylase. Proc Natl Acad Sci USA 1991 in press
    PubMedGoogle Scholar
  • 8 Soute B A M, Ulrich M M W, Vermeer C. Vitamin K-dependent carboxylase: increased efficiency of the carboxylation reaction. Thromb Haemostas 1987; 57: 77-81
    PubMedGoogle Scholar
  • 9 Thijssen H H W. Warfarin resistance: Vitamin K epoxide reductase of Scottish resistance genes is not irreversibly blocked by warfarin. Biochem Pharmacol 1987; 36: 2753-2757
    CrossrefPubMedGoogle Scholar
  • 10 Haroon Y, Shearer M J, Rahim S, Gunn W G, McEnery G, Barkhan P. The content of phylloquinone (vitamin K1) in human milk, cows' milk and infant formula foods determined by high-performance liquid chromatography. J Nutr 1982; 112: 1105-1117
    CrossrefPubMedGoogle Scholar
  • 11 Shearer M J. Personal communication
    PubMed
  • 12 Buitenhuis H C, Soute B A M, Vermeer C. Comparison of the vitamins K1, K2 and K3 as cofactors for the hepatic vitamin K-dependent carboxylase. Biochim Biophys Acta 1990; 1034: 170-175
    CrossrefPubMedGoogle Scholar
  • 13 Shearer M J, McCarthy P T, Crampton O E, Mattock M B. The assessment of human vitamin K status from tissue measurements. In: Current advances in vitamin K research. ( Suttie JW. ed ). Elsevier, New York: 1988. pp 437-452
    Google Scholar
  • 14 Suttie J W, Mummah-Schendel L L, Shah D V, Lyle B J, Greger J L. Vitamin K deficiency from dietary vitamin K restriction in humans. Am J Clin Nutr 1988; 47: 475-480
    CrossrefPubMedGoogle Scholar
  • 15 Gustafsson B E, Daft F S, McDaniel E G, Smith J C, Fitzgerald R J. Effects of vitamin K-active compounds and intestinal microorganisms in vitamin K-deficient germfree rats. J Nutr 1962; 78: 461-468
    CrossrefPubMedGoogle Scholar
  • 16 Creedon K A, Suttie J W. Effect of N-methyl-thiotetrazole on vitamin K epoxide reductase. Thrombos Res 1986; 44: 147-153
    CrossrefPubMedGoogle Scholar
  • 17 Roderick L M. A problem in the coagulation of the blood in 'sweet clover' disease of cattle. Am J Physiol 1931; 96: 413-425
    PubMedGoogle Scholar
  • 18 Campbell H A, Link K P. Studies on the hemorrhagic sweet clover disease. IV. The isolation and crystallisation of the hemorrhagic agent. J Biol Chem 1941; 138: 21-33
    PubMedGoogle Scholar
  • 19 Sixty Plus Reinfarction Study Research Group. A double-blind trial to assess long-term oral anticoagulant therapy in elderly patients after myocardial infarction. Lancet 1980 ii. 989-994
    PubMedGoogle Scholar
  • 20 Smith P, Arnesen H, Holme I. The effect of warfarin on morbidity and reinfarction after myocardial infarction. N Engl J Med 1990; 323: 147-152
    CrossrefPubMedGoogle Scholar
  • 21 Chong L-L, Chau W-K, Ho C-H. A case of 'superwarfarin' poisoning. Scand J Haematol 1986; 36: 314-315
    PubMedGoogle Scholar
  • 22 Lipton R A, Klass E M. Human ingestion of a 'superwarfarin' rodenticide resulting in a prolonged anticoagulant effect. JAMA 1984; 252: 3004-3005
    CrossrefPubMedGoogle Scholar
  • 23 Jones E C, Growe G H, Naiman S C. Prolonged anticoagulation in rat poisoning. JAMA 1984; 252: 3005-3007
    CrossrefPubMedGoogle Scholar
  • 24 Hauschka P V, Lian J B, Cole D E C, Gundberg CM. Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone. Phys Rev 1989; 69: 990-1047
    PubMedGoogle Scholar
  • 25 Van Haarlem L J M, Knapen M H J, Hamulyák K, Vermeer C. Circulating osteocalcin during oral anticoagulant therapy. Thromb Haemostas 1988; 60: 79-82
    PubMedGoogle Scholar
  • 26 Menon R K, Gill D S, Thomas M, Kernoff P B A, Dandona P. Impaired carboxylation of osteocalcin in warfarin-treated patients. J Clin Endocrinol Metab 1987; 64: 59-61
    CrossrefPubMedGoogle Scholar
  • 27 De Boer-van den Berg M A G, Vermeer C. The in vivo effects of oral anticoagulants in man: comparison between liver and non-hepatic tissues. Thromb Haemostas 1988; 59: 147-150
    PubMedGoogle Scholar
  • 28 Lipsky J J. Antibiotic-associated hypoprothrombinaemia. J Antimicr Chemother 1988; 21: 281-300
    CrossrefPubMedGoogle Scholar
  • 29 Kindberg C G, Suttie J W. Effect of various intakes of phylloquinone on signs of vitamin K deficiency and serum and liver phylloquinone concentrations in the rat. J Nutr 1989; 119: 175-180
    CrossrefPubMedGoogle Scholar
  • 30 Motohara K, Kuroki Y, Kan H, Endo F, Matsuda I. Detection of vitamin K deficiency by use of an enzyme-linked immunosorbent assay for circulating abnormal prothrombin. Pediatr Res 1985; 19: 354-357
    CrossrefPubMedGoogle Scholar
  • 31 Blanchard R A, Furie B C, Jorgensen M, Kruger S F, Furie B. Acquired vitamin K-dependent carboxylation deficiency in liver disease. N Engl J Med 1981; 305: 242-248
    CrossrefPubMedGoogle Scholar
  • 32 Widdershoven J, van Munster P, De Abreu R, Bosman H, van Lith T, van der Putten-van Meyel M, Motohara K, Matsuda I. Four methods compared for measuring de-carboxy-prothrombin (PIVKA-II). Clin Chem 1987; 33: 2074-2078
    PubMedGoogle Scholar
  • 33 Knapen M H J, Hamulyák K, Vermeer C. The effect of vitamin K supplementation on circulating osteocalcin (bone Gla-protein) and urinary calcium excretion. Ann Int Med 1989; 111: 1001-1005
    CrossrefPubMedGoogle Scholar
  • 34 Townsend C W. The hemorrhagic disease of the newborn. Arch Pediatr 1894; 11: 559-565
    Google Scholar
  • 35 Hamulyák K, de Boer-van den Berg MA G, Thijssen HH W, Hemker HC, Vermeer C. The placental transport of [3H] vitamin K1 in rats. Brit J Haematol 1987; 65: 335-338
    CrossrefPubMedGoogle Scholar
  • 36 Shearer M J, Rahim S, Barkhan P, Stimmler L. Plasma vitamin K1 in mothers and their newborn babies. Lancet 1982; ii: 460-463
    PubMedGoogle Scholar
  • 37 Motohara K, Endo F, Matsuda I. Effect of vitamin K administration on acarboxy prothrombin (PIVKA-II) levels in newborns. Lancet 1985; ii: 242-244
    PubMedGoogle Scholar
  • 38 Yao S-N, DeSilva A H, Kurachi S, Samuelson L C, Kurachi K. Characterization of a mouse factor IX cDNA and developmental regulation of the factor IX gene expression in liver. Thromb Haemostas 1991; 65: 52-58
    PubMedGoogle Scholar
  • 39 Price P A. Role of vitamin K-dependent proteins in bone metabolism. Annu Rev Nutr 1988; 8: 565-583
    CrossrefPubMedGoogle Scholar
  • 40 Fraser J D, Price P A. Lung, heart and kidney express high levels of mRNA for the vitamin K-dependent matrix Gla protein. J Biol Chem 1988; 263: 11033-11036
    PubMedGoogle Scholar
  • 41 Pettifor J M, Benson R. Congenital malformations associated with the administration of oral anticoagulants during pregnancy. J Pediatr 1975; 86: 459-462
    CrossrefPubMedGoogle Scholar
  • 42 Pauli R M, Lian J B, Mosher D F, Suttie J W. Association of congenital deficiency of multiple vitamin K-dependent coagulation factors and the phenotype of the warfarin embryopathy: clues to the mechanism of teratogenicity of coumarin derivatives. Am J Hum Gen 1987; 41: 566-583
    PubMedGoogle Scholar
  • 43 Gijsbers B L M G, van Haarlem L J M, Soute B A M, Ebberink R H M, Vermeer C. Characterization of a Gla-containing protein from calcified human atherosclerotic plaques. Arteriosclerosis 1990; 10: 991-995
    CrossrefPubMedGoogle Scholar
  • 44 Van Haarlem L J M, Soute B A M, Hemker H C, Vermeer C. Characterization of Gla-containing proteins from calcified human atherosclerotic plaques. In: Current Advances in Vitamin K Research.. ( Suttie JW. ed ). Elsevier North Holland, New York: 1988. pp 287-292
    Google Scholar
  • 45 Hauschka P V, Friedman P A, Traverso H P, Gallop P M. Vitamin K-dependent gammacarboxyglutamic acid formation by kidney microsomes in vitro. Biochem Biophys Res Commun 1976; 71: 1207-1213
    CrossrefPubMedGoogle Scholar
  • 46 Nakagawa Y, Achmed M, Hall S L, Deganello S, Coe F L. Isolation from human calcium oxalate renal stones of nephrocalcin, a glycoprotein inhibitor of calcium ocalate crystal growth. J Clin Invest 1987; 79: 1782-1787
    CrossrefPubMedGoogle Scholar
  • 47 Nakagawa Y, Abram V, Kézdy FJ, kaiser E T, Coe F L. Purification and characterization of the principal inhibitor of calcium monohydrate crystal growth in human urines. J Biol Chem 1983; 258: 12594-12600
    PubMedGoogle Scholar
  • 48 Nakagawa Y, Abram V, Parks J H, Lau H S-H, Kawooya J H, Coe F L. Urine glycoprotein crystal growth inhibitors. Evidence for a molecular abnormality in calcium oxalate nephtolithiasis. J Clin Invest 1985; 76: 1455-1462
    PubMedGoogle Scholar
  • 49 Hart J P, Catterall A, Dodds R A, Klenerman L, Shearer M.J. Bitensky L, Chayen J. Circulating vitamin K1 levels in fractured neck of femur. Lancet 1984; ii: 283
    PubMedGoogle Scholar
  • 50 Hart J P, Shearer M J, Klenerman L, Caterall A, Reeve J, Sambrook P N, Dodds R A, Bitensky L, Chayen J. Electrochemical detection of depressed circulating levels of vitamin K1 in osteoporosis. J Clin Endocrinol Metab 1985; 60: 1268-1269
    CrossrefPubMedGoogle Scholar
  • 51 Gijsbers B L M G, Jie K-S, Knapen M H J, Hamulyák K, Vermeer C. Effects of vitamin K and oral anticoagulants on urinary calcium excretion.. Thromb Haemostas, submitted for publication.
    PubMedGoogle Scholar
  • 52 Fiore C E, Tamburino C, Foti R, Grimaldi D. Reduced bone mineral content in patients taking an oral anticoagulant. South Med J 1990; 83: 538-542
    CrossrefPubMedGoogle Scholar