Download PDF
Thromb Haemost 1991; 66(01): 040-043
DOI: 10.1055/s-0038-1646371
Review Article
Schattauer GmbH Stuttgart

The Complexity of Platelet Adhesion to Extracellular Matrices

Richard O Hynes
Further Information

Publication History

Publication Date:
25 July 2018 (online)

  PDF Download  Permissions and Reprints
 

  • References

  • 1 Hynes RO. Integrins: a family of cell surface receptors. Cell ( 1987; ). 4: 549-554
    PubMedGoogle Scholar
  • 2 Ruoslahti E, Pierschbacher MD. New perspectives in cell adhesion: RGD and integrin. Science ( 1987; ). 238: 491-497
    CrossrefPubMedGoogle Scholar
  • 3 Albelda SM, Buck CA. Integrins and other cell adhesion molecules. FASEB J. ( 1990; ). 4: 2868-2880
    CrossrefPubMedGoogle Scholar
  • 4 Hemler ME. VLA proteins in the integrin family: Structures, functions and their role on leukocytes. Annu. Rev. Immunol. ( 1990; ). 8: 365-400
    CrossrefPubMedGoogle Scholar
  • 5 Kieffer N, Phillips DR. Platelet membrane glycoproteins: Functions in cellular interactions. Annu. Rev. Cell Biol. ( 1990; ). 6: 329-357
    CrossrefPubMedGoogle Scholar
  • 6 Newman PJ, Berndt NC, Gorski J, White II GC, Lyman S, Paddock C, Muller WA. PECAM-1(CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science ( 1990; ). 247: 1219-1222
    CrossrefPubMedGoogle Scholar
  • 7 Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B. PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell ( 1989; ). 59: 305-312
    CrossrefPubMedGoogle Scholar
  • 8 Hamburger SA, McEver RP. GMP-140 mediates adhesion of stimulated platelets to neutrophils. Blood ( 1990; ). 75: 550-554
    PubMedGoogle Scholar
  • 9 Schwarzbauer JE, Paul JI, Hynes RO. On the origin of species of fibronectin. Proc. Natl. Acad. Sci. USA, ( 1985; ). 81: 1424-1428
    PubMedGoogle Scholar
  • 10 Schwarzbauer JE, Spencer CS, Wilson CL. Selective secretion of alternatively spliced fibronectin variants. J. Cell Biol. ( 1989; ). 109: 3445-3453
    CrossrefPubMedGoogle Scholar
  • 11 Paul JI, Schwarzbauer JE, Tamkun JW, Hynes RO. Cell-type-specific fibronectin subunits generated by alternative splicing. J. Biol. Chem. ( 1986; ). 261: 12258-12265
    PubMedGoogle Scholar
  • 12 Hynes RO. Molecular Biology of Fibronectin. Ann. Rev. Cell Biol. ( 1985; ). 1: 67-90
    CrossrefPubMedGoogle Scholar
  • 13 Hynes RO. Fibronectins. Springer-Verlag, New York: ( 1990. )
    Google Scholar
  • 14 Wagner DD. Cell biology of von Willebrand factor. Annu. Rev. Cell Biol. ( 1990; ). 6: 217-246
    CrossrefPubMedGoogle Scholar
  • 15 O'Toole TE, Loftus JC, Du X, Glass AA, Ruggeri ZM, Shattil SJ, Plow EF, Ginsberg MH. Affinity modulation of the aIIbb3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Reg. ( 1990; ). 1: 883-893
    PubMedGoogle Scholar
  • 16 Ill CR, Engvall E, Ruoslahti E. Adhesion of platelets to laminin in the absence of activation. J. Cell Biol. ( 1984; ). 99: 2140-2145
    CrossrefPubMedGoogle Scholar
  • 17 Sonnenberg A, Janssen H, Hogervorst F, Calafat J, Hilgers J. A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody GoH3 MCAb. J. Biol. Chem. ( 1987; ). 262: 10376-10383
    PubMedGoogle Scholar
  • 18 Sonnenberg A, Moderman PW, Hogervorst F. Laminin receptor on platelets is the integrin VLA-6. Nature ( 1988; ). 336: 487-489
    CrossrefPubMedGoogle Scholar
  • 19 Piotrowicz RS, Orchekowski RP, Nugent DJ, Yamada KY, Kunicki TJ. Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets. J. Cell Biol. ( 1988; ). 106: 1359-1364
    CrossrefPubMedGoogle Scholar
  • 20 Hemler ME, Crouse C, Takada Y, Sonnenberg A. Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures. J. Biol. Chem. ( 1988; ). 263: 7660-7665
    PubMedGoogle Scholar
  • 21 Pischel KD, Bluestein HG, Woods Jr VL. Platelet glycoproteins Ia, Ic and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types. J. Clin. Invest. ( 1988; ). 81: 505-513
    CrossrefPubMedGoogle Scholar
  • 22 Kunicki TJ, Nugent DJ, Staats SJ, Orchekowski RP, Wayner EA, Carter WG. The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet glycoprotein Ia-IIa complex. J. Biol. Chem. ( 1988; ). 263: 4516-4519
    PubMedGoogle Scholar
  • 23 Lam SCT, Plow EF, D'Souza SE, Cheresh DA, Frelinger AL, Ginsberg MH. Isolation and characterization of a platelet membrane protein related to the vitronectin receptor. J. Biol. Chem. ( 1989; ). 264: 3742-3749
    PubMedGoogle Scholar
  • 24 Lawler J, Hynes RO. An integrin receptor on normal and thrombasthenic platlets which binds thrombospondin. Blood ( 1989; ). 74: 2022-2027
    PubMedGoogle Scholar
  • 25 Houdijk WP, Sakariassen KS, Nievelstein PF, Sixma JJ. Role of factor VIII-von Willebrand factor and fibronectin in the interaction of platelets in flowing blood with monomeric and fibrillar human collagen types I and III. J. Clin. Invest. ( 1985; ). 75: 531-540
    CrossrefPubMedGoogle Scholar
  • 26 Houdijk WP, de Groot PG, Nievelstein PF, Sakariassen KS, Sixma JJ. Subendothelial proteins and platelet adhesion. von Willebrand factor and fibronectin, not thrombospondin, are involved in platelet adhesion to extracellular matrix of human vascular endothelial cells. Arteriosclerosis ( 1986; ). 6: 24-33
    CrossrefPubMedGoogle Scholar
  • 27 Wayner EA, Carter WG, Piotrowicz RS, Kunicki TJ. The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifially inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa. J. Cell Biol. ( 1988; ). 107: 1881-1891
    CrossrefPubMedGoogle Scholar
  • 28 Coller BS, Folts JD, Smith SR, Scudder LE, Jordan R. Abolition of in vivo platelet thrombus formation in primates with monoclonal antibodies to the platelet GP IIb-IIIa receptor: correlation with bleeding time, platelet aggregation and blockade of GP IIb-IIIa receptors. Circulation ( 1989; ). 80: 1766-1774
    CrossrefPubMedGoogle Scholar
  • 29 Pytela R, Pierschbacher MD, Ginsberg MH, Plow EF, Ruoslahti E. Platelet membrane glycoprotein IIb/IIIa: member of a family of arg-gly-asp-specific adhesion receptors. Science ( 1986; ) 231: 1559-1562
    CrossrefPubMedGoogle Scholar
  • 30 Santoro SA, Rajpara SM, Staatz WD, Woods Jr VL. Isolation and characterization of a platelet surface collagen binding complex related to VLA-2. Biochem. Biophys. Res. Comm. ( 1988; ). 153: 217-223
    CrossrefPubMedGoogle Scholar
  • 31 Staatz WD, Rajpara SM, Wayner EA, Carter WG, Santoro SA. The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen. J. Cell Biol. ( 1989; ). 108: 1917-1924
    CrossrefPubMedGoogle Scholar
  • 32 Staatz WD, Walsh JJ, Pexton T, Santoro SA. The a2b1 integrin cell surface collagen receptor binds to the al(I)CB3 peptide of collagen. J. Biol. Chem. ( 1990; ). 265: 4778-4781
    PubMedGoogle Scholar
  • 33 Coller BS, Seligsohn U, Little PA. Type I Glanzmann thrombasthenia patients from the Iraqi-Jewish and Arab populations in Israel can be differentiated by platelet glycoprotein IIIa Immunoblot analysis. Blood ( 1987; ). 69: 1696-1703
    PubMedGoogle Scholar
  • 34 Loftus JC, O'Toole TE, Plow EF, Glass A, Frelinger 3d AL, Ginsberg MH. A b3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation. Science ( 1990; ). 249: 915-918
    CrossrefPubMedGoogle Scholar
  • 35 George JN, Nurden AT, Phillips DR. Molecular defects in interactions of platelets with the vessel wall. N. Engl. J. Med. ( 1984; ). 311: 1084-1098
    CrossrefPubMedGoogle Scholar
  • 36 Nieuwenhuis HK, Akkerman JWN, Houdjik WPM, Sixma JJ. Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia. Nature ( 1985; ). 318: 470-47
    CrossrefPubMedGoogle Scholar
  • 37 Hogan B, Costantini F, Lacy E. Manipulating the mouse embryo. A laboratory manual. Cold Spring Harbor Laboratory, New York: ( 1986. )
    Google Scholar
  • 38 Hanahan D. Transgenic mice as probes into complex systems. Science ( 1989; ). 246: 1265-1275
    CrossrefPubMedGoogle Scholar
  • 39 Thomas KR. Capecchi. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell ( 1987; ). 51: 503-512
    CrossrefPubMedGoogle Scholar
  • 40 Mansour SL, Thomas KR, Capecchi MR. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature ( 1988; ). 336: 348-352
    CrossrefPubMedGoogle Scholar
  • 41 Capecchi MR. Altering the genome by homologous recombination. Science ( 1989; ). 244: 1288-1292
    CrossrefPubMedGoogle Scholar
  • 42 Hasty P, Ramirez-Solis R, Krumlauf R, Bradley A. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Nature ( 1991; ). 350: 243-246
    CrossrefPubMedGoogle Scholar
  • 43 McMahon AP, Bradley A. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell ( 1990; ). 62: 1073-1085
    CrossrefPubMedGoogle Scholar
  • 44 Joyner AL, Herrup K, Auerbach BA, Davis CA, Rossant J. Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science ( 1991; ). 251: 1239-1243
    CrossrefPubMedGoogle Scholar
  • 45 Soriano P, Montgomery C, Geske R, Bradley A. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell ( 1991; ). 64: 693-702
    CrossrefPubMedGoogle Scholar
  • 46 Phillips DR, Agin PP. Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis. J. Biol. Chem. ( 1977; ). 252: 2121-2126
    PubMedGoogle Scholar