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CC BY-NC-ND 4.0 · J Neurol Surg Rep 2018; 79(02): e41-e54
DOI: 10.1055/s-0038-1645885
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Giant Cell Tumor of the Lateral Skull Base: Diagnostic and Management Options

Nicholas T. Gamboa
1   Department of Neurosurgery, Clinical Neurosciences Center, University of Utah School of Medicine, Salt Lake City, Utah, United States
,
Brenden Ronna
1   Department of Neurosurgery, Clinical Neurosciences Center, University of Utah School of Medicine, Salt Lake City, Utah, United States
,
Christina T. Gamboa
2   Department of Radiation Oncology, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
,
Cheryl A. Palmer
3   Division of Anatomic Pathology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States
,
Min S. Park
1   Department of Neurosurgery, Clinical Neurosciences Center, University of Utah School of Medicine, Salt Lake City, Utah, United States
,
Richard K. Gurgel
4   Division of Otolaryngology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, United States
,
William T. Couldwell
1   Department of Neurosurgery, Clinical Neurosciences Center, University of Utah School of Medicine, Salt Lake City, Utah, United States
,
M. Yashar S. Kalani
1   Department of Neurosurgery, Clinical Neurosciences Center, University of Utah School of Medicine, Salt Lake City, Utah, United States
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Publikationsverlauf

03. Juli 2017

27. Februar 2018

Publikationsdatum:
25. Mai 2018 (online)

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Abstract

Giant cell tumor of bone (GCTB) is a rare, benign, osteolytic neoplasm that most commonly occurs in early adulthood and often involves the long bones of the body. Although GCTB largely affects the epiphyses of long bones, several reports of GCTB involvement of the cranial and facial bones exist in the literature. In addition to reviewing other reported cases of GCTBs of the lateral skull base in the literature, the authors report here on the clinical presentation, radiographic findings, and neurosurgical management of a patient found to have a GCTB of the middle and infratemporal fossae, which was treated by aggressive en bloc resection of the lateral skull base.

Keywords

giant cell tumor of bone - lateral skull base tumor - neurosurgery - osteoclastoma - radiotherapy

Compliance with Ethical Standards

This study was approved by the Institutional Review Board (IRB) of the University of Utah.


Patient Consent

The patient/legal guardian/next of kin has consented to the submission of the case report for submission to the Journal of Neurological Surgery Reports.


 

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