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DOI: 10.1055/s-0038-1627763
Der Verlauf bipolarer Störungen
Gibt es neue Erkenntnisse?The course of bipolar disordersAre there new findings?Publikationsverlauf
eingegangen:
04. Oktober 2014
angenommen:
04. Oktober 2014
Publikationsdatum:
22. Januar 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00034916/201412/lookinside/thumbnails/10-1055-s-0038-1627763_de-1.jpg)
Zusammenfassung
Verlaufsbeobachtungen sind von zentraler Bedeutung für das Verständnis bipolar affektiver Störungen. Eine reiche Literatur zu diesem Thema nennt auch entsprechende Prädiktoren. Dieser Artikel stellt neue Herangehensweisen vor: 1. Staging-Modelle bipolar affektiver Störungen, 2. die Frage zur Existenz des Kindling-Phänomens, 3. die Frage zum Einfluss der Polarität auf den Verlauf, 4. Überlegungen zur Entität „bipolare Störung” und 5. der Einfluss von Versorgungskonzepten auf den Verlauf bipolarer Störungen. Eine kritische, reflektierte und patientenorientierte Herangehensweise ohne Dogma tut Not.
Summary
Observation of the course of bipolar disorder is of central importance for its understanding. There are several studies that have reported predictors. The paper presents new concepts: 1. Staging models of bipolar affective disorders, 2. a discussion whether “kindling phenomena” exist in reality, 3. the influence of polarity on the illness course, 4. a discussion whether bipolar affective disorders form an “entity” and 5. new concepts of collaborative care. There is a need for a critical, reflecting and patient-oriented attitude without any dogma.
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Literatur
- 1 Angst J, Preisig M. Course of a clinical cohort of unipolar, bipolar and schizoaffective patients. Results of a prospective study from 1959 to 1985. Schweiz Arch Neurol Psychiatr 1995; 146 (01) 5-16.
- 2 Angst J, Preisig M. Outcome of a clinical cohort of unipolar, bipolar and schizoaffective patients. Results of a prospective study from 1959 to 1985. Schweiz Arch Neurol Psychiatr 1995; 146 (01) 17-23.
- 3 Angst J, Sellaro R, Stassen HH, Gamma A. Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissions. J Affect Disord 2005; 84 (2–3): 149-157.
- 4 Baldessarini RJ, Tondo L, Visioli C. First-episode types in bipolar disorder: predictive associations with later illness. Acta Psychiatr Scand 2014; 129 (05) 383-392.
- 5 Bauer MS, McBride L, Williford WO. et al. Collaborative care for bipolar disorder: part I. Intervention and implementation in a randomized effectiveness trial. Psychiatr Serv 2006; 57 (07) 927-936.
- 6 Berk M, Brnabic A, Dodd S. et al. Does stage of illness impact treatment response in bipolar disorder? Empirical treatment data and their implication for the staging model and early intervention. Bipolar Disorders 2011; 13 (01) 87-98.
- 7 Brieger P, Marneros PrognoseA. In Deutsche Gesellschaft für Bipolare Störungen e.V). Weißbuch Bipolare Störungen in Deutschland. Stand des Wissens. Defizite. Was ist zu tun?. Hamburg: ConferencePoint; 2006
- 8 Brieger P. Komorbidität bei bipolar affektiven Störungen. Nervenheilkunde 2011; 30: 309-312.
- 9 Brieger P, Pfennig A, Juckel G. Die Versorgung bipolar affektiver Störungen. In: Assion H-J, Brieger P, Bauer M. (Eds.) Bipolare Störungen. Das Praxishandbuch. Stuttgart: Kohlhammer; 2013
- 10 Cheniaux E, Landeira-Fernandez J, Versiani M. The diagnoses of schizophrenia, schizoaffective disorder, bipolar disorder and unipolar depression: interrater reliability and congruence between DSM-IV and ICD-10. Psychopathology 2009; 42 (05) 293-298.
- 11 Ciompi L, Müller C. Lebensweg und Alter der Schizophrenen. Eine katamnestische Langzeitstudie bis ins Senium. Heidelberg: Springer; 1976
- 12 Craddock N, Owen MJ. The Kraepelinian dichotomy – going, going. but still not gone. The British Journal of Psychiatry 2010; 196 (02) 92-95.
- 13 Finseth PI, Morken G, Malt UF. et al. Risk factors of cycle acceleration in acutely admitted patients with bipolar disorder. Acta Psychiatr Scand 2014; 130 (05) 388-396.
- 14 Frances A, Jones KD. Bipolar disorder type II revisited. Bipolar Disord 2012; 14 (05) 474-477.
- 15 Ghaemi SN. DSM-5 and the miracle that never happens. Acta Psychiatr Scand 2014; 129 (06) 410-412.
- 16 Goldberg JF, Harrow M, Whiteside JE. Risk for Bipolar Illness in Patients Initially Hospitalized for Unipolar Depression. Am J Psychiatry 2001; 158 (08) 1265-1270.
- 17 Goldberg JF, Harrow M. A 15-year prospective follow-up of bipolar affective disorders: comparisons with unipolar nonpsychotic depression. Bipolar Disorders 2011; 13 (02) 155-163.
- 18 Goodwin FK, Jamison KR. Manic-depressive illness. Bipolar Disorders and Recurrent Depression. 2nd. New York: Oxford University Press; 2007
- 19 Hart J. The inverse care law. Lancet 1971; 27: 405-412.
- 20 Huber G, Gross G, Schüttler R. Schizophrenie. Eine verlaufsund sozialpsychiatrische Langzeitstudie. Heidelberg: Springer; 1979
- 21 Jäger M, Lang FU, Frasch K, Becker T. Schizophrene Psychosen mit bipolarem Verlauf – Implikationen für Nosologie und Therapie. Fortschr Neurol Psychiatr 2012; 80 (09) 520-526.
- 22 Judd LL, Akiskal HS, Schettler PJ. et al. The longterm natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002; 59 (06) 530-537.
- 23 Kapczinski F, Magalhaes PV, Balanza-Martinez V. et al. Staging systems in bipolar disorder: an International Society for Bipolar Disorders Task Force Report. Acta Psychiatr Scand 2014; 130 (05) 354-363.
- 24 Kessing LV, Hansen MG, Andersen PK, Angst J. The predictive effect of episodes on the risk of recurrence in depressive and bipolar disorders – a life-long perspective. Acta Psychiatr Scand 2004; 109 (05) 339-344.
- 25 Kessing LV, Hansen HV, Hvenegaard A. et al. Treatment in a specialised out-patient mood disorder clinic v. standard out-patient treatment in the early course of bipolar disorder: randomised clinical trial. Br J Psychiatry 2013; 202 (03) 212-219.
- 26 Kessing LV, Vradi E, Andersen PK. Starting lithium prophylaxis early v. late in bipolar disorder. Br J Psychiatry 2013; 202 (03) 212-219.
- 27 Kotov R, Leong SH, Mojtabai R. et al. Boundaries of schizoaffective disorder: revisiting Kraepelin. JAMA Psychiatry 2013; 70 (12) 1276-1286.
- 28 Lobban F, Taylor L, Chandler C. et al. Enhanced relapse prevention for bipolar disorder by community mental health teams: cluster feasibility randomised trial. Br J Psychiatry 2010; 196 (01) 59-63.
- 29 Magalhaes PV, Dodd S, Nierenberg AA, Berk M. Cumulative morbidity and prognostic staging of illness in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Australian and New Zealand Journal of Psychiatry 2012; 46 (11) 1058-1067.
- 30 Maj M, Pirozzi R, Magliano L. Late non-response to lithium prophylaxis in bipolar patients: prevalence and predictors. J Affect Disord 1996; 39 (01) 39-42.
- 31 Marneros A, Deister A, Rohde A. Affektive, schizoaffektive und schizophrene Psychosen. Eine vergleichende Langzeitstudie. Berlin: Springer; 1991
- 32 Marneros A, Angst J. Bipolar disorders: roots and evolution. In: Marneros A, Angst J. (Eds.) Bipolar disorders: 100 years after manic-depressive insanity. London: Kluwer Academic Publishers; 2000
- 33 Marneros A, Brieger P. The prognosis of bipolar disorder. In: Maj M, Sartorius N, Ibor J-JL, Akiskal HS. (eds). Bipolar Disorders. Chichester: Wiley; 2002
- 34 Peralta V, Cuesta MJ. Exploring the borders of the schizoaffective spectrum: a categorical and dimensional approach. J Affect Disord 2008; 108 (1–2): 71-86.
- 35 Popovic D, Torrent C, Goikolea JM. et al. Clinical implications of predominant polarity and the polarity index in bipolar disorder: a naturalistic study. Acta Psychiatr Scand 2014; 129 (05) 366-374.
- 36 Post RM. Sensitization and kindling perspectives for the course of affective illness: toward a new treatment with the anticonvulsant carbamazepine. Pharmacopsychiatry 1990; 23 (01) 3-17.
- 37 Wigman JT, van Nierop M, Vollebergh WA. et al. Evidence that psychotic symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk, and severity – implications for diagnosis and ultra-high risk research. Schizophr Bull 2012; 38 (02) 247-257.
- 38 Wittchen HU, Lieb R, Pfister H, Schuster P. The waxing and waning of mental disorders: evaluating the stability of syndromes of mental disorders in the population. Compr Psychiatry 2000; 41 (02) Suppl (Suppl. 01) 122-132.
- 39 Zinkler M, Koussemou JM. Menschenrechte in der Psychiatrie – Wege und Hindernisse zu einem umfassenden Gewaltverzicht. Recht & Psychiatrie 2014; 32: 142-147.