J Reconstr Microsurg 2018; 34(06): 420-427
DOI: 10.1055/s-0038-1626691
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Simplifying Arterial Coupling in Microsurgery—A Preclinical Assessment of an Everter Device to Aid with Arterial Anastomosis

Ian C. Sando
1   Section of Plastic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan
,
Jeffrey S. Plott
2   Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan
,
Brendan M. McCracken
3   Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan
4   Michigan Center for Integrative Research in Critical Care (MCIRCC), University of Michigan, Ann Arbor, Michigan
,
Mohamad H. Tiba
3   Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan
4   Michigan Center for Integrative Research in Critical Care (MCIRCC), University of Michigan, Ann Arbor, Michigan
,
Kevin R. Ward
3   Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan
4   Michigan Center for Integrative Research in Critical Care (MCIRCC), University of Michigan, Ann Arbor, Michigan
,
Jeffrey H. Kozlow
1   Section of Plastic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan
,
Paul S. Cederna
1   Section of Plastic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan
,
Adeyiza O. Momoh
1   Section of Plastic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan
› Author Affiliations
Further Information

Publication History

14 November 2017

23 December 2017

Publication Date:
16 February 2018 (online)

Abstract

Background A novel arterial everter device was engineered to simplify microvascular coupling of arteries by reliably securing the stiff, muscular wall of arteries over coupler pins. We compare microvascular coupling with the everter device to manual suturing for arterial anastomoses in a live large animal model.

Materials and Methods In this preliminary study, bilateral external femoral arteries of five male swine were exposed and sharply divided. Arteries were anastomosed using either interrupted sutures (n = 5) or the everter device and Synovis Coupler (n = 5). The efficiency in engaging coupler pins, the time taken to perform the anastomosis, and vessel patency immediately post-op and at 1-week postanastomosis were evaluated. Vessel wall injury and luminal stenosis were compared between groups using histomorphometric analyses.

Results On an average, 80% of coupler pins engaged the vessel walls after a single pass of the everter. The average time to perform the anastomosis was significantly less when using the everter/coupler compared with manual suturing (6:35 minutes versus 25:09 minutes, p < 0.001). Immediately post-op, 100% patency was observed in both groups. At 1 week post-op, four of five (80%) of coupled arteries and all five (100%) of hand-sewn arteries were patent. The degree of arterial wall injury, neointimal formation, and luminal stenosis for patent arteries were similar between groups.

Conclusions Successful arterial anastomoses using the everter device with the Synovis Coupler was easier and significantly more efficient when compared with a standard hand-sewn technique. Both techniques had acceptable patency rates and similar effects on the vessel wall and intima.

 
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