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Nuklearmedizin 1976; 15(03): 152-155
DOI: 10.1055/s-0038-1624951
Originalarbeiten — Original Articles
Schattauer GmbH

Absorbed Radiation Dose from Radionuclidic Impurities in Several 123I-Labeled Radiopharmaceuticals

Absorbierte Strahlendosis durch die radioaktiven Verunreinigungen der verschiedenen 123J-markierten Radiopharmazeutika
L. G. Colombetti   *
1   From the Loyola University, Stritch School of Medicine and Division of Nuclear Medicine, Michael Reese Hospital and Medical Center, Chicago/Ill. 60616
,
W. E. Barnes   **
1   From the Loyola University, Stritch School of Medicine and Division of Nuclear Medicine, Michael Reese Hospital and Medical Center, Chicago/Ill. 60616
› Author Affiliations
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Publication History

Received:12 January 1976

Publication Date:
11 January 2018 (online)

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Summary

The radiation dose to patients from RISA, sodium iodohippurate, and rose bengal labeled with commercially available 123I and its accompanying radio-impurities has been studied. The extra radiation dose to target organs was found to range from 29% to 97% that due to 123I alone when the radiopharmaceutical is administered at calibration time. Additional delay in the time of administration increases the relative impurity dose.

Es wurde die Bestrahlungsdosis bei Patienten nach Gabe von RISA, Jodhippurat und Bengalrosa untersucht, welche mit dem handelsüblichen 123J und dessen radioaktiven Verunreinigungen markiert waren. Die zusätzliche Strahlenbelastung der kritischen Organe wurde in einer Größenordnung von 29 bis 97 % gefunden gegenüber der alleinigen Belastung durch 123J wenn die Anwendung auf die „calibration time” bezogen ist. Zusätzliche Verzögerungen bis zur Anwendungszeit lassen die relative Verunreinigungsdosis anwachsen.

* Loyola University Stritch School of Medicine and Division of Nuclear Medicine, Michael Reese Hospital & Medical Center, Chicago, Ill.


** Nuclear Medicine Service, Veterans Administration Hospital, Hines, Ill.


 

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