J Pediatr Infect Dis
DOI: 10.1055/s-0037-1620249
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Intravenous Immunoglobulin for Congenital Parvovirus Myocarditis

Yonatan Kurland
1  Department of Pediatrics, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
,
Ranjit I. Kylat
1  Department of Pediatrics, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
2  Section of Neonatal-Perinatal Medicine and Developmental Biology, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
,
Drew C. Johnson
1  Department of Pediatrics, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
,
Brent J. Barber
1  Department of Pediatrics, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
3  Section of Pediatric Cardiology, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
,
Alan D. Bedrick
1  Department of Pediatrics, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
2  Section of Neonatal-Perinatal Medicine and Developmental Biology, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
,
Mohammad Y. Bader
1  Department of Pediatrics, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
2  Section of Neonatal-Perinatal Medicine and Developmental Biology, Arizona Health Sciences Center, The University of Arizona, Tucson, Arizona, United States
› Author Affiliations
Further Information

Publication History

07 November 2017

06 December 2017

Publication Date:
18 January 2018 (eFirst)

Abstract

Congenital parvovirus infection has a diverse presentation ranging from asymptomatic infants to intrauterine demise secondary to red cell aplasia or myocarditis. Treatment is aimed at correcting anemia with intrauterine and postnatal transfusions. We report a case of fetal hydrops with severe atrioventricular regurgitation and myocardial dysfunction secondary to parvovirus infection in a preterm infant. Myocarditis and myocardial dysfunction responded to immunoglobulin administration.