Thromb Haemost 2001; 86(02): 534-537
DOI: 10.1055/s-0037-1616082
Review Article
Schattauer GmbH

The Value of Ultrasound Screening for Proximal Vein Thrombosis after Total Hip Arthroplasty

A Prospective Cohort Study
Fabio Verlato
1   Unit Care of Angiology
,
Olinto Bruchi
2   S. Anthony Unit Care of Anesthesiology
,
Paolo Prandoni
3   Second Department of Internal Medicine, University Hospital of Padua, Italy
,
Giuseppe Camporese
1   Unit Care of Angiology
,
Gianni Maso
2   S. Anthony Unit Care of Anesthesiology
,
Flavio Busonera
1   Unit Care of Angiology
,
Antonio Girolami
3   Second Department of Internal Medicine, University Hospital of Padua, Italy
,
Giuseppe Maria Andreozzi*
1   Unit Care of Angiology
,
for the W. O. D. O. S. Investigators Group › Author Affiliations
Further Information

Publication History

Received 09 October 2000

Accepted after resubmission 28 February 2001

Publication Date:
12 December 2017 (online)

Summary

The role of ultrasound screening for proximal deep-vein thrombosis (DVT) following major hip surgery is controversial. 202 consecutive patients, who had received warfarin prophylaxis after total hip arthroplasty underwent a bilateral ultrasound assessment of the proximal vein system (using the criterion of vein compressibility) before hospital discharge. In the 9 patients (4.5%; 95% CI, 2.1-8.3%) with positive test anticoagulant treatment was successfully continued for three months. In all the remaining 193 patients the warfarin treatment was withdrawn. A second ultrasound test was performed 15 days later, and showed a new (asymptomatic) abnormality compatible with proximal DVT in 2 patients (1.0%; 95% CI, 0.1-3.7%). All other 191 patients remained asymptomatic until the completion of a 3-month follow-up period (rate of symptomatic thromboembolism, 0/191, 0%; 95% CI, 0-1.9%).

Because of the relatively high incidence of proximal DVT in patients undergoing major orthopaedic surgery under warfarin prophylaxis, screening for proximal DVT at hospital discharge in these patients is indicated. The negativity of this test has the potential of safely preventing the extension of anticoagulation beyond hospital stay. A larger controlled study in which the value of this strategy is tested against the prolongation of oral anticoagulation in patients with a negative ultrasound screening at discharge is indicated.

* Other authors participating in the Warfarin Optimal Duration Orthopaedic Study (W. O. D. O. S.): Vittorio Aneloni, Andrea Camposampiero, Federica Rosso, Paola Sabbion, Cinzia Tanduo.


 
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