PDF herunterladen
Thromb Haemost 2000; 84(05): 928
DOI: 10.1055/s-0037-1614145
Letters to the Editor
Schattauer GmbH

Clopidogrel but not Ticlopidine Produces an Antiplatelet Effect in the Yucatan Minipig

Jeffrey S. Bostwick
1   From the Departments of Cardiovascular Drug Discovery, Drug Metabolism and Pharmacokinetics, and Laboratory Animal Resources, A ventis Pharmaceuticals, Research and Development, Collegeville, PA, USA
,
Stephanie Costanzo   a
1   From the Departments of Cardiovascular Drug Discovery, Drug Metabolism and Pharmacokinetics, and Laboratory Animal Resources, A ventis Pharmaceuticals, Research and Development, Collegeville, PA, USA
,
Lisa Byan   b
1   From the Departments of Cardiovascular Drug Discovery, Drug Metabolism and Pharmacokinetics, and Laboratory Animal Resources, A ventis Pharmaceuticals, Research and Development, Collegeville, PA, USA
,
Yongyi Luo
1   From the Departments of Cardiovascular Drug Discovery, Drug Metabolism and Pharmacokinetics, and Laboratory Animal Resources, A ventis Pharmaceuticals, Research and Development, Collegeville, PA, USA
,
Chandra Natarajan
1   From the Departments of Cardiovascular Drug Discovery, Drug Metabolism and Pharmacokinetics, and Laboratory Animal Resources, A ventis Pharmaceuticals, Research and Development, Collegeville, PA, USA
,
Glenda Bilder   c
1   From the Departments of Cardiovascular Drug Discovery, Drug Metabolism and Pharmacokinetics, and Laboratory Animal Resources, A ventis Pharmaceuticals, Research and Development, Collegeville, PA, USA
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 31. März 2000

Accepted 04. April 2000

Publikationsdatum:
13. Dezember 2017 (online)

Auch verfügbar auf
    Lizenzen und Reprints

 

a Stephanie Costanzo, Du Pont Pharmaceuticals, Wilmington, DE


b Lisa Byan, Guilford Pharmaceutical, Baltimore, MD


c Glenda Bilder, Valleybrook Corporate Center, Suite 310, Malvern, PA, USA


 

  • References

  • 1 Griggs TR, Bauman RW, Reddick RL, Read MS, Koch GG, Lamb MA. Development of coronary atherosclerosis in swine with severe hypercholesterolemia: Lack of influence of von Willebrand factor or acute intimal injury. Arteriosclerosis 1986; 06: 155-65.
    CrossrefPubMedSuche in Google Scholar
  • 2 Karas SP, Gravanis MB, Santoian EC, Robinson KA, Anderberg KA, King SB. Coronary intimal proliferation after balloon injury and stenting in swine: An animal model of restenosis. J Am Coll Cardiol 1992; 20: 467-74.
    CrossrefPubMedSuche in Google Scholar
  • 3 Schwartz RS, Murphy JG, Edwards WD, Camrud AR, Vliestra RE, Holmes DR. Restenosis after balloon angioplasty: A practical proliferative model in porcine coronary arteries. Circulation 1990; 82: 2190-200.
    CrossrefPubMedSuche in Google Scholar
  • 4 Bilder G, Wentz T, Leadley R, Amin D, Byan L, O’Conner B, Needle S, Galczenski H, Bostwick J, Kasiewski K, Myers M, Spada A, Merkle L, Ly C, Persons P, Page K, Perrone M, Dunwiddie C. Restenosis following angioplasty in the swine coronary artery is inhibited by an orally active PDG F-receptor tyrosine kinase inhibitor, RPR101511A. Circulation 1999; 99: 3292-9.
    CrossrefPubMedSuche in Google Scholar
  • 5 Jeong MH, Kang KC, Holmes DR, Schwartz RS. Combination of aspirin and ticlopidine is effective in the prevention of acute stent thrombosis. Chonnam J Med Sci 1997; 10 (01) 27-34.
    PubMedSuche in Google Scholar