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Thromb Haemost 2000; 84(02): 359-360
DOI: 10.1055/s-0037-1614026
Letters to the Editor
Schattauer GmbH

Oral Ethinyl Estradiol, but not Transdermal 17β-estradiol, Increases Plasma C-reactive Protein Levels in Men

Erik J. Giltay
1   From the Research Institute for Endocrinology, Reproduction and Metabolism, the Netherlands
,
Louis J. G. Gooren
1   From the Research Institute for Endocrinology, Reproduction and Metabolism, the Netherlands
,
Jef J. Emeis
2   The Gaubius Laboratory, TNO-PG, Leiden, the Netherlands
,
Teake Kooistra
2   The Gaubius Laboratory, TNO-PG, Leiden, the Netherlands
,
Coen D. A. Stehouwer
3   The Department of Internal Medicine, University Hospital Vrije Universiteit, Amsterdam, the Netherlands
› Author Affiliations
Further Information

Publication History

Received 27 March 2000

Accepted 03 April 2000

Publication Date:
14 December 2017 (online)

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  • References

  • 1 Niculescu F, Rus HG, Vlaicu R. Immunohistochemical localization of C5b-9, S-protein, C3d and apolipoprotein B in human arterial tissues with atherosclerosis. Atherosclerosis 1987; 65: 1-11.
    CrossrefPubMedSearch in Google Scholar
  • 2 Liuzzo G, Biasucci LM, Gallimore JR, Grille RL, Rebuzzi AG, Pepys MB, Maseri A. The prognostic value of C-reactive protein and serum amyloid protein in severe unstable angina. N Engl J Med 1994; 331: 417-24.
    CrossrefPubMedSearch in Google Scholar
  • 3 Thompson SG, Kienast J, Pyke SDM, Haverkate F, Van De Loo JCW. for the European Concerted Action on Thrombosis and disabilities angina pectoris study. Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. N Engl J Med 1995; 332: 635-41.
    CrossrefPubMedSearch in Google Scholar
  • 4 Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997; 336: 973-9.
    CrossrefPubMedSearch in Google Scholar
  • 5 Cushman M, Legault C, Barrett-Connor E, Stefanick ML, Kessler C, Judd HL, Sakkinen PA, Tracy RP. Effects of postmenopausal hormones on inflammation-sensitive proteins: the Postmenopausal Estrogen/Progestin Interventions (PEPI) study. Circulation 1999; 100: 717-22.
    CrossrefPubMedSearch in Google Scholar
  • 6 Van Baal WM, Kenemans P, Van Der Mooren MJ, Kessel H, Emeis JJ, Stehouwer CDA. Increased C-reactive protein levels during short-term hormone replacement therapy in healthy postmenopausal women. Thromb Haemost 1999; 81: 925-8.
    Thieme ConnectPubMedSearch in Google Scholar
  • 7 Chetkowski RJ, Meldrum DR, Steingold KA, Randle D, Lu IK, Eggena P, Hershman JM, Alkjaersig NK, Fletcher AP, Judd HL. Biologic effects of transdermal estradiol. N Engl J Med 1986; 314: 1615-20.
    CrossrefPubMedSearch in Google Scholar
  • 8 Giltay EJ, Gooren LJG, Emeis J, Kooistra T, Stehouwer CDA. Oral, but not transdermal, administration of estrogens lowers tissue-type plasminogen activator levels without affecting its endothelial synthesis. Arterioscler Thromb Vase Biol 2000; 20: 1396-403.
    CrossrefPubMedSearch in Google Scholar
  • 9 Ridker PM, Hennekens CH, Rifai N, Buring JE, Manson JE. Hormone replacement therapy and increased plasma concentration of C-reactive protein. Circulation 1999; 100: 713-6.
    CrossrefPubMedSearch in Google Scholar
  • 10 Sattar N, Perera M, Small M, Lumsden MA. Hormone replacement therapy and sensitive C-reactive protein concentrations in women with type-2 diabetes. Lancet 1999; 354: 487-8.
    CrossrefPubMedSearch in Google Scholar