Download PDF
Thromb Haemost 2000; 83(02): 352-354
DOI: 10.1055/s-0037-1613817
Letters to the Editor
Schattauer GmbH

Comparison of the Risk of Pulmonary Embolism and Deep Vein Thrombosis in the Presence of Factor V Leiden or Prothrombin G20210A

A. J. González Ordóñez
1   From the Hematology Dept., Hospital Central de Asturias, Oviedo, Spain
,
J. M. Fernández Carreira
2   Research Unit, Hospital S. Agustin, Avilés, Hospital Central de Asturias, Oviedo, Spain
,
C. R. Fernández Alvarez
1   From the Hematology Dept., Hospital Central de Asturias, Oviedo, Spain
,
J.M. Medina Rodríguez
1   From the Hematology Dept., Hospital Central de Asturias, Oviedo, Spain
,
M. V. Alvarez
3   Molecular Genetic Dept., Hospital Central de Asturias, Oviedo, Spain
,
E. Coto
3   Molecular Genetic Dept., Hospital Central de Asturias, Oviedo, Spain
› Author Affiliations
Further Information

Publication History

Received 05 August 1999

Accepted after resubmission 22 October 1999

Publication Date:
11 December 2017 (online)

Also available at
    Permissions and Reprints

 

 

  • References

  • 1 Turkstra F, Karemaker R, Kuijer PMM, Prins MH, Büller HR. Is the prevalence of the factor V Leiden mutation in patients with pulmonary embolism and deep vein thrombosis really different?. Thromb Haemost 1999; 81: 345-8.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 2 Desmarais S, de Moerloose Ph, Reber G, Minazio Ph, Perrier A, Bounameaux H. Resistance to activated protein C in an unselected population of patients with pulmonary embolism. Lancet 1996; 347: 1374-5.
    CrossrefPubMedGoogle Scholar
  • 3 Manten B, Westendorp RGJ, Koster T, Reitsma PH, Rosendaal FR. Risk factor profiles in patients with different clinical manifestations of venous thromboembolism: a focus on the factor V Leiden mutation. Thromb Haemost 1996; 76: 510-3.
    PubMedGoogle Scholar
  • 4 Martinelli I, Cattaneo M, Panzeri D, Mannucci PM. Low prevalence of factor V:Q506 in 41 patients with isolated pulmonary embolism. Thromb Haemost 1997; 77: 440-3.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Baglin TP, Brown K, Williamson D, Baker P, Luddington R. Relative risk of pulmonary embolism and deep vein thrombosis in association with the factor V Leiden mutation in a United Kingdom population. Thromb Haemost 1997; 77: 1219.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Mari D, Mannucci PM, Duca F, Bertolini S, Franceschi C. Mutant factor V Leiden in healthy centenarians. Lancet 1996; 347: 1044.
    PubMedGoogle Scholar
  • 7 Mannucci PM, Mari D, Merati G, Peyvandi F, Tagliabue L, Sacchi E, Taioli E, Sansoni P, Bertolini S, Franceschi C. Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins. A study in centenarians. Arterioscler Thromb Vasc Biol 1997; 17: 755-9.
    CrossrefPubMedGoogle Scholar
  • 8 Hille ET, Westendorp RG, Vandenbroucke JP, Rosendaal FR. Mortality and causes of death in families with the factor V Leiden mutation (resistance to activated protein C). Blood 1997; 89: 1963-7.
    PubMedGoogle Scholar
  • 9 Rees DC, Liu YT, Cox MJ, Elliot P, Wainscoat JS. Factor V Leiden and thermolabile methylenetetrahydrofolate reductase in extreme old age. Thromb Haemost 1997; 78: 1357-9.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 10 Heijmans BT, Westendorp RG, Knook DL, Kluft C, Slagboom PE. The risk of mortality and the factor V Leiden mutation in a population-based cohort. Thromb Haemost 1998; 80: 607-9.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 11 Reuner KH, Ruf A, Litfin F, Patscheke H. The mutation G20210→A in the prothrombin gene is a strong risk factor for pulmonary embolism. Clin Chem 1998; 44: 1365-6.
    PubMedGoogle Scholar