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Thromb Haemost 2004; 92(03): 486-494
DOI: 10.1055/s-0037-1613739
Theme Issue Article
Schattauer GmbH

Murine thrombosis models

Sharlene M. Day
1   Departments of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
,
Jennifer L. Reeve
1   Departments of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
,
Daniel D. Myers
2   Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA
,
William P. Fay
1   Departments of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
› Author AffiliationsFinancial support: This work was supported by NIH grants HL65224 and HL57346 (WPF) and by NIH T32 Training Grant HL07853 (SMD).
Further Information

Publication History

Received 14 May 2004

Accepted after revision 28 June 2004

Publication Date:
15 December 2017 (online)

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Summary

Due to exciting advances in molecular biology, the laboratory mouse has become an important and frequently used model for studying thrombosis. This article reviews several experimental approaches that have been used to study arterial, venous, and microvascular thrombosis in mice. The advantages and limitations of different models are examined. Related topics of mouse anesthesia, phlebotomy, and in vitro hemostasis testing are also reviewed.

Keywords

Mouse or murine - animal models - thrombosis - haemostasis
 

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