Preparation of Rearranged Allylic Isocyanates from the Reaction of Allylic Alcohols with 1-Cyano-4-dimethylaminopyridinium Bromide

Abstract

A shorter and less costly alternative to Ichikawa’s [1,3]-transposition protocol for cyanates to isocyanates is described.

Key words

sigmatropic rearrangement - [1,3]-transposition - allylic ­alcohol - methodology - total synthesis

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