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Synthesis 2018; 50(23): 4690-4694
DOI: 10.1055/s-0037-1610221
DOI: 10.1055/s-0037-1610221
paper
Stereoselective Synthesis of d 4-(S)-Lysine from (S)-Serine
Financial support from the Deutsche Forschungsgemeinschaft is gratefully acknowledged.Further Information
Publication History
Received: 09 May 2018
Accepted after revision: 28 June 2018
Publication Date:
24 July 2018 (online)


Abstract
Tetradeuterated (S)-lysine can easily be obtained from protected (S)-serine in a few steps including a Cu-mediated cross coupling and subsequent platinum-catalysed deuteration.
Supporting Information
- Supporting information for this article (copies of NMR spectra) is available online at https://doi.org/10.1055/s-0037-1610221.
- Supporting Information