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DOI: 10.1055/s-0037-1604299
New Treatment Approaches to Arteriovenous Malformations
Publication History
Publication Date:
11 September 2017 (online)
Abstract
Arteriovenous malformations (AVMs) are high-flow vascular anomalies that have demonstrated a very high recurrence rate after endovascular treatment, surgical treatment, or a combination of both. Surgical treatments have shown good response when they are small and well localized but a poor response when diffuse. A better understanding of the nature of the lesion has led to a better response rate and a safer treatment for these patients. This has been accomplished through a detailed understanding of the angioarchitecture of the lesion, enabling a tailored approach in reaching and targeting the nidus of the AVM with different liquid embolic agents, more specifically ethanol. Flow reduction techniques help in exposing the nidus to sclerosant agents. A clinical classification, the Schobinger classification, will help determine the appropriate time to start or to pursue therapy.
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References
- 1 Mulliken JB, Glowacki J. Classification of pediatric vascular lesions. Plast Reconstr Surg 1982; 70 (01) 120-121
- 2 Yakes WF, Rossi P, Odink H. How I do it. Arteriovenous malformation management. Cardiovasc Intervent Radiol 1996; 19 (02) 65-71
- 3 Burrows PE, Laor T, Paltiel H, Robertson RL. Diagnostic imaging in the evaluation of vascular birthmarks. Dermatol Clin 1998; 16 (03) 455-488
- 4 Kohout MP, Hansen M, Pribaz JJ, Mulliken JB. Arteriovenous malformations of the head and neck: natural history and management. Plast Reconstr Surg 1998; 102 (03) 643-654
- 5 Vander Kam V, Achauer BM. Arteriovenous malformations: a team approach to management. Plast Surg Nurs 1995; 15 (01) 53-57
- 6 Enjolras O. Classification and management of the various superficial vascular anomalies: hemangiomas and vascular malformations. J Dermatol 1997; 24 (11) 701-710
- 7 Lee BB, Baumgartner I, Berlien HP. , et al; International Union of Angiology. Consensus document of the International Union of Angiology (IUA)-2013. Current concept on the management of arterio-venous management. Int Angiol 2013; 32 (01) 9-36
- 8 Finn MC, Glowacki J, Mulliken JB. Congenital vascular lesions: clinical application of a new classification. J Pediatr Surg 1983; 18 (06) 894-900
- 9 Cho SK, Do YS, Shin SW. , et al. Arteriovenous malformations of the body and extremities: analysis of therapeutic outcomes and approaches according to a modified angiographic classification. J Endovasc Ther 2006; 13 (04) 527-538
- 10 Yakes W, Baumgartner I. Interventional treatment of arterio-venous malformations. Gefasschirurgie 2014; 19 (04) 325-330
- 11 Revencu N, Boon LM, Mulliken JB. , et al. Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused by RASA1 mutations. Hum Mutat 2008; 29 (07) 959-965
- 12 Kurek KC, Howard E, Tennant LB. , et al. PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes. Am J Surg Pathol 2012; 36 (05) 671-687
- 13 Tan WH, Baris HN, Burrows PE. , et al. The spectrum of vascular anomalies in patients with PTEN mutations: implications for diagnosis and management. J Med Genet 2007; 44 (09) 594-602
- 14 Dubois J, Soulez G, Oliva VL, Berthiaume MJ, Lapierre C, Therasse E. Soft-tissue venous malformations in adult patients: imaging and therapeutic issues. Radiographics 2001; 21 (06) 1519-1531
- 15 Hovius SE, Borg DH, Paans PR, Pieterman H. The diagnostic value of magnetic resonance imaging in combination with angiography in patients with vascular malformations: a prospective study. Ann Plast Surg 1996; 37 (03) 278-285
- 16 Siegel MJ. Magnetic resonance imaging of musculoskeletal soft tissue masses. Radiol Clin North Am 2001; 39 (04) 701-720
- 17 Reinacher PC, Stracke P, Reinges MH, Hans FJ, Krings T. Contrast-enhanced time-resolved 3-D MRA: applications in neurosurgery and interventional neuroradiology. Neuroradiology 2007; 49 (Suppl. 01) S3-S13
- 18 Saleh RS, Lohan DG, Villablanca JP, Duckwiler G, Kee ST, Finn JP. Assessment of craniospinal arteriovenous malformations at 3T with highly temporally and highly spatially resolved contrast-enhanced MR angiography. AJNR Am J Neuroradiol 2008; 29 (05) 1024-1031
- 19 Taschner CA, Gieseke J, Le Thuc V. , et al. Intracranial arteriovenous malformation: time-resolved contrast-enhanced MR angiography with combination of parallel imaging, keyhole acquisition, and k-space sampling techniques at 1.5 T. Radiology 2008; 246 (03) 871-879
- 20 Wu Y, Kim N, Korosec FR. , et al. 3D time-resolved contrast-enhanced cerebrovascular MR angiography with subsecond frame update times using radial k-space trajectories and highly constrained projection reconstruction. AJNR Am J Neuroradiol 2007; 28 (10) 2001-2004
- 21 Ziyeh S, Strecker R, Berlis A, Weber J, Klisch J, Mader I. Dynamic 3D MR angiography of intra- and extracranial vascular malformations at 3T: a technical note. AJNR Am J Neuroradiol 2005; 26 (03) 630-634
- 22 Tao Q, Lv B, Bhatia KS, Qiao B, Zheng CQ, Chen ZF. Three-dimensional CT angiography for the diagnosis and assessment of arteriovenous malformations in the oral and maxillofacial region. J Craniomaxillofac Surg 2010; 38 (01) 32-37
- 23 Mulliken JB, Fishman SJ, Burrows PE. Vascular anomalies. Curr Probl Surg 2000; 37 (08) 517-584
- 24 Upton J, Coombs CJ, Mulliken JB, Burrows PE, Pap S. Vascular malformations of the upper limb: a review of 270 patients. J Hand Surg Am 1999; 24 (05) 1019-1035
- 25 Liu AS, Mulliken JB, Zurakowski D, Fishman SJ, Greene AK. Extracranial arteriovenous malformations: natural progression and recurrence after treatment. Plast Reconstr Surg 2010; 125 (04) 1185-1194
- 26 Goldenberg DC, Hiraki PY, Caldas JG, Puglia P, Marques TM, Gemperli R. Surgical treatment of extracranial arteriovenous malformations after multiple embolizations: outcomes in a series of 31 patients. Plast Reconstr Surg 2015; 135 (02) 543-552
- 27 Qiu Y, Chen H, Lin X, Hu X, Jin Y, Ma G. Outcomes and complications of sclerotherapy for venous malformations. Vasc Endovascular Surg 2013; 47 (06) 454-461
- 28 Do YS, Yakes WF, Shin SW. , et al. Ethanol embolization of arteriovenous malformations: interim results. Radiology 2005; 235 (02) 674-682
- 29 Prasetyono TO, Kreshanti P. Efficacy of intra-lesional alcohol injection as alternative and/or complementary treatment of vascular malformations: a systematic review. J Plast Reconstr Aesthet Surg 2010; 63 (07) 1071-1079
- 30 Jackson JE, Mansfield AO, Allison DJ. Treatment of high-flow vascular malformations by venous embolization aided by flow occlusion techniques. Cardiovasc Intervent Radiol 1996; 19 (05) 323-328
- 31 Legiehn GM, Heran MK. Classification, diagnosis, and interventional radiologic management of vascular malformations. Orthop Clin North Am 2006; 37 (03) 435-474 , vii–viii
- 32 Kim JS, Nam MH, Do YS. , et al. Efficacy of milrinone versus nitroglycerin in controlling pulmonary arterial hypertension induced by intravenous injections of absolute ethanol in anesthetized dogs. J Vasc Interv Radiol 2010; 21 (06) 882-887
- 33 Shin BS, Do YS, Cho HS. , et al. Effects of repeat bolus ethanol injections on cardiopulmonary hemodynamic changes during embolotherapy of arteriovenous malformations of the extremities. J Vasc Interv Radiol 2010; 21 (01) 81-89
- 34 Rao VR, Mandalam KR, Gupta AK, Kumar S, Joseph S. Dissolution of isobutyl 2-cyanoacrylate on long-term follow-up. AJNR Am J Neuroradiol 1989; 10 (01) 135-141
- 35 Chiu AH, Aw G, Wenderoth JD. Double-lumen arterial balloon catheter technique for Onyx embolization of dural arteriovenous fistulas: initial experience. J Neurointerv Surg 2014; 6 (05) 400-403
- 36 Bauer AM, Bain MD, Rasmussen PA. Onyx resorbtion with AVM recanalization after complete AVM obliteration. Interv Neuroradiol 2015; 21 (03) 351-356
- 37 Shin BS, Do YS, Cho HS. , et al. Cardiovascular effects and predictability of cardiovascular collapse after repeated intravenous bolus injections of absolute ethanol in anesthetized pigs. J Vasc Interv Radiol 2010; 21 (12) 1867-1872
- 38 Kitagawa A, Izumi Y, Hagihara M. , et al. Ethanolamine oleate sclerotherapy combined with transarterial embolization using n-butyl cyanoacrylate for extracranial arteriovenous malformations. Cardiovasc Intervent Radiol 2014; 37 (02) 371-380
- 39 Cassinotto C, Lapuyade B. Pancreatic arteriovenous malformation embolization with onyx. J Vasc Interv Radiol 2015; 26 (03) 442-444
- 40 Su L, Wang D, Han Y, Wang Z, Zheng L, Fan X. Absolute ethanol embolization of infiltrating-diffuse extracranial arteriovenous malformations in the head and neck. Eur J Vasc Endovasc Surg 2015; 50 (01) 114-121
- 41 Wohlgemuth WA, Müller-Wille R, Teusch VI. , et al. The retrograde transvenous push-through method: a novel treatment of peripheral arteriovenous malformations with dominant venous outflow. Cardiovasc Intervent Radiol 2015; 38 (03) 623-631
- 42 van der Linden E, van Baalen JM, Pattynama PM. Retrograde transvenous ethanol embolization of high-flow peripheral arteriovenous malformations. Cardiovasc Intervent Radiol 2012; 35 (04) 820-825
- 43 Numan F, Omeroglu A, Kara B, Cantaşdemir M, Adaletli I, Kantarci F. Embolization of peripheral vascular malformations with ethylene vinyl alcohol copolymer (Onyx). J Vasc Interv Radiol 2004; 15 (09) 939-946