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DOI: 10.1055/s-0037-1604065
Is Pethidine Safe during Labor? Systematic Review
A petidina é segura durante o trabalho de parto? Revisão sistemáticaPublication History
23 February 2017
19 April 2017
Publication Date:
30 June 2017 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00030576/201712/lookinside/thumbnails/10-1055-s-0037-1604065_5964-1.jpg)
Abstract
Purpose To verify if pethidine is safe for the conceptus when used during labor.
Methods Systematic review in the Capes Periodicals/PubMed and MEDLINE/Virtual Health Library (BVS, in the Portuguese acronym) databases.
Results A total of 17 studies published from January 1st, 2000, to September 2nd, 2016, with a total of 1,688 participants involved were included in the present review. There was no record of conceptus vitality decrease associated with low doses of pethidine being administered to mothers during labor.
Conclusions Intramuscular (IM) or intravenous (IV) pethidine at low doses, of up to 50 mg, is safe to administer during labor.
Resumo
Objetivo Verificar se a petidina é segura para o concepto quando utilizada durante o trabalho de parto.
Método Revisão sistemática nas bases de dados dos Periódicos Capes/PubMed e MEDLINE/Biblioteca Virtual em Saúde (BVS).
Resultados Um total de 17 estudos, publicados de 1° de janeiro de 2000 a 2 de setembro de 2016, totalizando 1.688 participantes envolvidos, foram incluídos nesta revisão. Não houve registro de depressão na vitalidade dos conceptos com doses baixas de petidina administradas às mães durante o trabalho de parto.
Conclusão Petidina intramuscular (IM) ou intravenosa (IV) em baixas doses, de até 50 mg, é segura durante o trabalho de parto.
Note
This study was conducted in partnership with Universidade de of Fortaleza (UNIFOR), through the access granted to the digital library of the institution. The authors are part of the MSc Academic Course in Medical Sciences at UNIFOR.
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