Effect of Prophylactic Thoracic Duct Ligation in Reducing the Incidence of Postoperative Chylothorax during Esophagectomy: A Systematic Review and Meta-analysis

Yiyan Lei; Yanfen Feng; Bo Zeng; Xin Zhang; Jingfu Chen; Jianyong Zou; Chunhua Su; Zhenguo Liu; Honghe Luo; Shuishen Zhang

doi:10.1055/s-0037-1602259

The Thoracic and Cardiovascular Surgeon, Inhaltsverzeichnis

Thorac Cardiovasc Surg 2018; 66(05): 370-375
DOI: 10.1055/s-0037-1602259

Original Thoracic

Georg Thieme Verlag KG Stuttgart · New York

Effect of Prophylactic Thoracic Duct Ligation in Reducing the Incidence of Postoperative Chylothorax during Esophagectomy: A Systematic Review and Meta-analysis

Yiyan Lei

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

,

Yanfen Feng

²State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P. R. China

³Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P. R. China

,

Bo Zeng

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

,

Xin Zhang

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

,

Jingfu Chen

⁴Department of Oncology, The Third People's Hospital of Dongguan City, Dongguan, Guangdong, P. R. China

,

Jianyong Zou

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

,

Chunhua Su

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

,

Zhenguo Liu

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

,

Honghe Luo

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

,

Shuishen Zhang

¹Department of Thoracic Surgery, Sun Yat-sen University, the First Affiliated Hospital, Guangzhou, Guangdong, P. R. China

› Institutsangaben

Abstract

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Abstract

Objectives There is no consensus on the effectiveness of prophylactic thoracic duct ligation (PLG) in esophagectomy for reducing the incidence of postoperative chylothorax. We performed a systemic review and meta-analysis to study its efficacy.

Methods A systemic review of the publications was performed on three databases to identify all the relevant literature on comparative outcomes of PLG and nonprophylactic thoracic duct ligation (NPLG). The primary end point was the incidence of postoperative chylothorax.

Results Seven studies with comparative data on PLG (n = 2,178) versus NPLG (n = 3,048) were identify from the current publications. Comparison showed no significant difference between PLG and NPLG on the incidence of postoperative chylothorax (relative risk = 0.431; 95% confidence interval, 0.186 to 1.002; p = 0.050).

Conclusions Although some studies showed that PLG during the esophagectomy was effective to lower the incidence of postoperative chylothorax, no evidence was observed in the present meta-analysis. Further research is warranted to validate the findings.

Keywords

prophylactic thoracic duct ligation - chylothorax - esophagectomy - meta-analysis

Volltext

Referenzen

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