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Semin Musculoskelet Radiol 2017; 21(02): 102-112
DOI: 10.1055/s-0037-1599204
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Ultrasound of the Knee: Common Pathology Excluding Extensor Mechanism

Jon A. Jacobson
1   Department of Radiology, University of Michigan, Ann Arbor, Michigan
,
Thumanoon Ruangchaijatuporn
2   Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchatewi, Bangkok, Thailand
,
Viviane Khoury
3   Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
,
Olaf Magerkurth
4   Department of Radiology, Kantonsspital Baden, Baden, Switzerland
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Publikationsdatum:
29. März 2017 (online)

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Abstract

Ultrasound can be used to diagnose many types of pathology and guide various diagnostic or therapeutic procedures. The most common applications for musculoskeletal ultrasound of the knee include evaluation of the joint recesses, the extensor mechanism, and bursae including Baker's cyst. However, a role exists for ultrasound in the evaluation of cartilage, other tendons, ligaments, peripheral nerves, osseous structures, and vasculature. This article reviews common pathologies of these structures as seen with ultrasound. In addition, various ultrasound-guided procedures pertaining to these pathologies are introduced. The importance of a comprehensive evaluation is also emphasized as a method to maximize information gained from the ultrasound examination.

Keywords

knee - ultrasound - musculoskeletal - pathology
 

  • References

  • 1 Yablon CM, Melville DM, Jacobson JA. Ultrasound of the knee. AJR Am J Roentgenol 2014; 202 (3) W284
    CrossrefPubMedGoogle Scholar
  • 2 Lee MJ, Chow K. Ultrasound of the knee. Semin Musculoskelet Radiol 2007; 11 (2) 137-148
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 3 Fenn S, Datir A, Saifuddin A. Synovial recesses of the knee: MR imaging review of anatomical and pathological features. Skeletal Radiol 2009; 38 (4) 317-328
    CrossrefPubMedGoogle Scholar
  • 4 Spinner RJ, Amrami KK, Rock MG. The use of MR arthrography to document an occult joint communication in a recurrent peroneal intraneural ganglion. Skeletal Radiol 2006; 35 (3) 172-179
    CrossrefPubMedGoogle Scholar
  • 5 Mandl P, Brossard M, Aegerter P , et al. Ultrasound evaluation of fluid in knee recesses at varying degrees of flexion. Arthritis Care Res (Hoboken) 2012; 64 (5) 773-779
    CrossrefPubMedGoogle Scholar
  • 6 Strouse PJ, DiPietro MA, Adler RS. Pediatric hip effusions: evaluation with power Doppler sonography. Radiology 1998; 206 (3) 731-735
    CrossrefPubMedGoogle Scholar
  • 7 Wakefield RJ, Balint PV, Szkudlarek M , et al; OMERACT 7 Special Interest Group. Musculoskeletal ultrasound including definitions for ultrasonographic pathology. J Rheumatol 2005; 32 (12) 2485-2487
    PubMedGoogle Scholar
  • 8 Roberts D, Miller TT, Erlanger SM. Sonographic appearance of primary synovial chondromatosis of the knee. J Ultrasound Med 2004; 23 (5) 707-709
    CrossrefPubMedGoogle Scholar
  • 9 Sibbitt Jr WL, Kettwich LG, Band PA , et al. Does ultrasound guidance improve the outcomes of arthrocentesis and corticosteroid injection of the knee?. Scand J Rheumatol 2012; 41 (1) 66-72
    CrossrefPubMedGoogle Scholar
  • 10 Park Y, Lee SC, Nam HS, Lee J, Nam SH. Comparison of sonographically guided intra-articular injections at 3 different sites of the knee. J Ultrasound Med 2011; 30 (12) 1669-1676
    CrossrefPubMedGoogle Scholar
  • 11 Aisen AM, McCune WJ, MacGuire A , et al. Sonographic evaluation of the cartilage of the knee. Radiology 1984; 153 (3) 781-784
    CrossrefPubMedGoogle Scholar
  • 12 Tsai CY, Lee CL, Chai CY , et al. The validity of in vitro ultrasonographic grading of osteoarthritic femoral condylar cartilage—a comparison with histologic grading. Osteoarthritis Cartilage 2007; 15 (3) 245-250
    CrossrefPubMedGoogle Scholar
  • 13 Yoon CH, Kim HS, Ju JH, Jee WH, Park SH, Kim HY. Validity of the sonographic longitudinal sagittal image for assessment of the cartilage thickness in the knee osteoarthritis. Clin Rheumatol 2008; 27 (12) 1507-1516
    CrossrefPubMedGoogle Scholar
  • 14 Thiele RG. Role of ultrasound and other advanced imaging in the diagnosis and management of gout. Curr Rheumatol Rep 2011; 13 (2) 146-153
    CrossrefPubMedGoogle Scholar
  • 15 Thiele RG, Schlesinger N. Diagnosis of gout by ultrasound. Rheumatology (Oxford) 2007; 46 (7) 1116-1121
    CrossrefPubMedGoogle Scholar
  • 16 Ogdie A, Taylor WJ, Weatherall M , et al. Imaging modalities for the classification of gout: systematic literature review and meta-analysis. Ann Rheum Dis 2015; 74 (10) 1868-1874
    CrossrefPubMedGoogle Scholar
  • 17 Thiele RG, Schlesinger N. Ultrasonography shows disappearance of monosodium urate crystal deposition on hyaline cartilage after sustained normouricemia is achieved. Rheumatol Int 2010; 30 (4) 495-503
    CrossrefPubMedGoogle Scholar
  • 18 Filippucci E, Riveros MG, Georgescu D, Salaffi F, Grassi W. Hyaline cartilage involvement in patients with gout and calcium pyrophosphate deposition disease. An ultrasound study. Osteoarthritis Cartilage 2009; 17 (2) 178-181
    CrossrefPubMedGoogle Scholar
  • 19 Akatsu Y, Yamaguchi S, Mukoyama S , et al. Accuracy of high-resolution ultrasound in the detection of meniscal tears and determination of the visible area of menisci. J Bone Joint Surg Am 2015; 97 (10) 799-806
    CrossrefPubMedGoogle Scholar
  • 20 Seymour R, Lloyd DC. Sonographic appearances of meniscal cysts. J Clin Ultrasound 1998; 26 (1) 15-20
    CrossrefPubMedGoogle Scholar
  • 21 Frediani B, Filippou G, Falsetti P , et al. Diagnosis of calcium pyrophosphate dihydrate crystal deposition disease: ultrasonographic criteria proposed. Ann Rheum Dis 2005; 64 (4) 638-640
    CrossrefPubMedGoogle Scholar
  • 22 Macmahon PJ, Brennan DD, Duke D, Forde S, Eustace SJ. Ultrasound-guided percutaneous drainage of meniscal cysts: preliminary clinical experience. Clin Radiol 2007; 62 (7) 683-687
    CrossrefPubMedGoogle Scholar
  • 23 Smith MK, Lesniak B, Baraga MG, Kaplan L, Jose J. Treatment of popliteal (Baker) cysts with ultrasound-guided aspiration, fenestration, and injection: long-term follow-up. Sports Health 2015; 7 (5) 409-414
    CrossrefPubMedGoogle Scholar
  • 24 Ward EE, Jacobson JA, Fessell DP, Hayes CW, van Holsbeeck M. Sonographic detection of Baker's cysts: comparison with MR imaging. AJR Am J Roentgenol 2001; 176 (2) 373-380
    CrossrefPubMedGoogle Scholar
  • 25 Rothstein CP, Laorr A, Helms CA, Tirman PF. Semimembranosus-tibial collateral ligament bursitis: MR imaging findings. AJR Am J Roentgenol 1996; 166 (4) 875-877
    CrossrefPubMedGoogle Scholar
  • 26 Forbes JR, Helms CA, Janzen DL. Acute pes anserine bursitis: MR imaging. Radiology 1995; 194 (2) 525-527
    CrossrefPubMedGoogle Scholar
  • 27 Aguiar RO, Viegas FC, Fernandez RY, Trudell D, Haghighi P, Resnick D. The prepatellar bursa: cadaveric investigation of regional anatomy with MRI after sonographically guided bursography. AJR Am J Roentgenol 2007; 188 (4) W355-8
    PubMedGoogle Scholar
  • 28 Viegas FC, Aguiar RO, Gasparetto E , et al. Deep and superficial infrapatellar bursae: cadaveric investigation of regional anatomy using magnetic resonance after ultrasound-guided bursography. Skeletal Radiol 2007; 36 (1) 41-46
    CrossrefPubMedGoogle Scholar
  • 29 Muhle C, Ahn JM, Yeh L , et al. Iliotibial band friction syndrome: MR imaging findings in 16 patients and MR arthrographic study of six cadaveric knees. Radiology 1999; 212 (1) 103-110
    CrossrefPubMedGoogle Scholar
  • 30 Uson J, Aguado P, Bernad M , et al. Pes anserinus tendino-bursitis: what are we talking about?. Scand J Rheumatol 2000; 29 (3) 184-186
    CrossrefPubMedGoogle Scholar
  • 31 Di Sante L, Paoloni M, Ioppolo F, Dimaggio M, Di Renzo S, Santilli V. Ultrasound-guided aspiration and corticosteroid injection of Baker's cysts in knee osteoarthritis: a prospective observational study. Am J Phys Med Rehabil 2010; 89 (12) 970-975
    CrossrefPubMedGoogle Scholar
  • 32 Bandinelli F, Fedi R, Generini S , et al. Longitudinal ultrasound and clinical follow-up of Baker's cysts injection with steroids in knee osteoarthritis. Clin Rheumatol 2012; 31 (4) 727-731
    CrossrefPubMedGoogle Scholar
  • 33 Finnoff JT, Nutz DJ, Henning PT, Hollman JH, Smith J. Accuracy of ultrasound-guided versus unguided pes anserinus bursa injections. PM R 2010; 2 (8) 732-739
    CrossrefPubMedGoogle Scholar
  • 34 La S, Fessell DP, Femino JE, Jacobson JA, Jamadar D, Hayes C. Sonography of partial-thickness quadriceps tendon tears with surgical correlation. J Ultrasound Med 2003; 22 (12) 1323-1329 ; quiz 1330–1331
    CrossrefPubMedGoogle Scholar
  • 35 Wangwinyuvirat M, Dirim B, Pastore D , et al. Prepatellar quadriceps continuation: MRI of cadavers with gross anatomic and histologic correlation. AJR Am J Roentgenol 2009; 192 (3) W111-W116
    CrossrefPubMedGoogle Scholar
  • 36 Roberts VI, Mereddy PK, Donnachie NJ, Hakkalamani S. Anatomical variations in vastus medialis obliquus and its implications in minimally-invasive total knee replacement. An MRI study. J Bone Joint Surg Br 2007; 89 (11) 1462-1465
    PubMedGoogle Scholar
  • 37 Lundquist RB, Matcuk Jr GR, Schein AJ , et al. Posteromedial corner of the knee: the neglected corner. Radiographics 2015; 35 (4) 1123-1137
    CrossrefPubMedGoogle Scholar
  • 38 Munshi M, Pretterklieber ML, Kwak S, Antonio GE, Trudell DJ, Resnick D. MR imaging, MR arthrography, and specimen correlation of the posterolateral corner of the knee: an anatomic study. AJR Am J Roentgenol 2003; 180 (4) 1095-1101
    CrossrefPubMedGoogle Scholar
  • 39 Smith J, Sayeed YA, Finnoff JT, Levy BA, Martinoli C. The bifurcating distal biceps femoris tendon: potential pitfall in musculoskeletal sonography. J Ultrasound Med 2011; 30 (8) 1162-1166
    CrossrefPubMedGoogle Scholar
  • 40 Marchand AJ, Proisy M, Ropars M, Cohen M, Duvauferrier R, Guillin R. Snapping knee: imaging findings with an emphasis on dynamic sonography. AJR Am J Roentgenol 2012; 199 (1) 142-150
    CrossrefPubMedGoogle Scholar
  • 41 Mallinson PI, Reagan AC, Coupal T, Munk PL, Ouellette H, Nicolaou S. The distribution of urate deposition within the extremities in gout: a review of 148 dual-energy CT cases. Skeletal Radiol 2014; 43 (3) 277-281
    CrossrefPubMedGoogle Scholar
  • 42 Fernandes EA, Lopes MG, Mitraud SA, Ferrari AJ, Fernandes AR. Ultrasound characteristics of gouty tophi in the olecranon bursa and evaluation of their reproducibility. Eur J Radiol 2012; 81 (2) 317-323
    CrossrefPubMedGoogle Scholar
  • 43 Pineda C, Amezcua-Guerra LM, Solano C , et al. Joint and tendon subclinical involvement suggestive of gouty arthritis in asymptomatic hyperuricemia: an ultrasound controlled study. Arthritis Res Ther 2011; 13 (1) R4
    CrossrefPubMedGoogle Scholar
  • 44 Puig JG, de Miguel E, Castillo MC, Rocha AL, Martínez MA, Torres RJ. Asymptomatic hyperuricemia: impact of ultrasonography. Nucleosides Nucleotides Nucleic Acids 2008; 27 (6) 592-595
    CrossrefPubMedGoogle Scholar
  • 45 Chiavaras MM, Jacobson JA. Ultrasound-guided tendon fenestration. Semin Musculoskelet Radiol 2013; 17 (1) 85-90
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 46 Kampa RJ, Connell DA. Treatment of tendinopathy: is there a role for autologous whole blood and platelet rich plasma injection?. Int J Clin Pract 2010; 64 (13) 1813-1823
    CrossrefPubMedGoogle Scholar
  • 47 Sheth U, Simunovic N, Klein G , et al. Efficacy of autologous platelet-rich plasma use for orthopaedic indications: a meta-analysis. J Bone Joint Surg Am 2012; 94 (4) 298-307
    CrossrefPubMedGoogle Scholar
  • 48 De Maeseneer M, Van Roy F, Lenchik L, Barbaix E, De Ridder F, Osteaux M. Three layers of the medial capsular and supporting structures of the knee: MR imaging-anatomic correlation. Radiographics 2000; 20 (Spec No): S83-S89
    CrossrefPubMedGoogle Scholar
  • 49 Huang GS, Yu JS, Munshi M , et al. Avulsion fracture of the head of the fibula (the “arcuate” sign): MR imaging findings predictive of injuries to the posterolateral ligaments and posterior cruciate ligament. AJR Am J Roentgenol 2003; 180 (2) 381-387
    CrossrefPubMedGoogle Scholar
  • 50 Cavaignac E, Wytrykowski K, Reina N , et al. Ultrasonographic identification of the anterolateral ligament of the knee. Arthroscopy 2016; 32 (1) 120-126
    CrossrefPubMedGoogle Scholar
  • 51 Hsu CC, Tsai WC, Chen CP, Yeh WL, Tang SF, Kuo JK. Ultrasonographic examination of the normal and injured posterior cruciate ligament. J Clin Ultrasound 2005; 33 (6) 277-282
    CrossrefPubMedGoogle Scholar
  • 52 Ptasznik R, Feller J, Bartlett J, Fitt G, Mitchell A, Hennessy O. The value of sonography in the diagnosis of traumatic rupture of the anterior cruciate ligament of the knee. AJR Am J Roentgenol 1995; 164 (6) 1461-1463
    CrossrefPubMedGoogle Scholar
  • 53 Sekiya JK, Jacobson JA, Wojtys EM. Sonographic imaging of the posterolateral structures of the knee: findings in human cadavers. Arthroscopy 2002; 18 (8) 872-881
    CrossrefPubMedGoogle Scholar
  • 54 LaPrade MD, Kennedy MI, Wijdicks CA, LaPrade RF. Anatomy and biomechanics of the medial side of the knee and their surgical implications. Sports Med Arthrosc Rev 2015; 23 (2) 63-70
    CrossrefPubMedGoogle Scholar
  • 55 Cho KH, Lee DC, Chhem RK , et al. Normal and acutely torn posterior cruciate ligament of the knee at US evaluation: preliminary experience. Radiology 2001; 219 (2) 375-380
    CrossrefPubMedGoogle Scholar
  • 56 DeFriend DE, Schranz PJ, Silver DA. Ultrasound-guided aspiration of posterior cruciate ligament ganglion cysts. Skeletal Radiol 2001; 30 (7) 411-414
    CrossrefPubMedGoogle Scholar
  • 57 Podesta L, Crow SA, Volkmer D, Bert T, Yocum LA. Treatment of partial ulnar collateral ligament tears in the elbow with platelet-rich plasma. Am J Sports Med 2013; 41 (7) 1689-1694
    CrossrefPubMedGoogle Scholar
  • 58 Yablon CM, Hammer MR, Morag Y, Brandon CJ, Fessell DP, Jacobson JA. US of the peripheral nerves of the lower extremity: a landmark approach. Radiographics 2016; 36 (2) 464-478
    CrossrefPubMedGoogle Scholar
  • 59 Canella C, Demondion X, Guillin R, Boutry N, Peltier J, Cotten A. Anatomic study of the superficial peroneal nerve using sonography. AJR Am J Roentgenol 2009; 193 (1) 174-179
    CrossrefPubMedGoogle Scholar
  • 60 Le Corroller T, Lagier A, Pirro N, Champsaur P. Anatomical study of the infrapatellar branch of the saphenous nerve using ultrasonography. Muscle Nerve 2011; 44 (1) 50-54
    CrossrefPubMedGoogle Scholar
  • 61 Silvestri E, Martinoli C, Derchi LE, Bertolotto M, Chiaramondia M, Rosenberg I. Echotexture of peripheral nerves: correlation between US and histologic findings and criteria to differentiate tendons. Radiology 1995; 197 (1) 291-296
    CrossrefPubMedGoogle Scholar
  • 62 Tagliafico A, Altafini L, Garello I, Marchetti A, Gennaro S, Martinoli C. Traumatic neuropathies: spectrum of imaging findings and postoperative assessment. Semin Musculoskelet Radiol 2010; 14 (5) 512-522
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 63 Grant TH, Omar IM, Dumanian GA, Pomeranz CB, Lewis VA. Sonographic evaluation of common peroneal neuropathy in patients with foot drop. J Ultrasound Med 2015; 34 (4) 705-711
    CrossrefPubMedGoogle Scholar
  • 64 Spinner RJ, Carmichael SW, Atkinson JL. Intraneural ganglion cyst. J Neurosurg 2006; 104 (6) 990-992 ; author reply 992
    CrossrefPubMedGoogle Scholar
  • 65 Spinner RJ, Desy NM, Amrami KK. Sequential tibial and peroneal intraneural ganglia arising from the superior tibiofibular joint. Skeletal Radiol 2008; 37 (1) 79-84
    CrossrefPubMedGoogle Scholar
  • 66 Spinner RJ, Desy NM, Rock MG, Amrami KK. Peroneal intraneural ganglia. Part I. Techniques for successful diagnosis and treatment. Neurosurg Focus 2007; 22 (6) E16
    PubMedGoogle Scholar
  • 67 Spinner RJ, Luthra G, Desy NM, Anderson ML, Amrami KK. The clock face guide to peroneal intraneural ganglia: critical “times” and sites for accurate diagnosis. Skeletal Radiol 2008; 37 (12) 1091-1099
    CrossrefPubMedGoogle Scholar
  • 68 Spinner RJ, Mokhtarzadeh A, Schiefer TK, Krishnan KG, Kliot M, Amrami KK. The clinico-anatomic explanation for tibial intraneural ganglion cysts arising from the superior tibiofibular joint. Skeletal Radiol 2007; 36 (4) 281-292
    CrossrefPubMedGoogle Scholar
  • 69 Young NP, Sorenson EJ, Spinner RJ, Daube JR. Clinical and electrodiagnostic correlates of peroneal intraneural ganglia. Neurology 2009; 72 (5) 447-452
    CrossrefPubMedGoogle Scholar
  • 70 Zhu J, Liu F, Li D, Shao J, Hu B. Preliminary study of the types of traumatic peripheral nerve injuries by ultrasound. Eur Radiol 2011; 21 (5) 1097-1101
    CrossrefPubMedGoogle Scholar
  • 71 Ruffilli A, De Fine M, Traina F, Pilla F, Fenga D, Faldini C. Saphenous nerve injury during hamstring tendons harvest: Does the incision matter? A systematic review. Knee Surg Sports Traumatol Arthrosc 2016 ; June 23 (Epub ahead of print)
    PubMedGoogle Scholar
  • 72 Reynolds Jr DL, Jacobson JA, Inampudi P, Jamadar DA, Ebrahim FS, Hayes CW. Sonographic characteristics of peripheral nerve sheath tumors. AJR Am J Roentgenol 2004; 182 (3) 741-744
    CrossrefPubMedGoogle Scholar
  • 73 Ryu JA, Lee SH, Cha EY, Kim TY, Kim SM, Shin MJ. Sonographic differentiation between schwannomas and neurofibromas in the musculoskeletal system. J Ultrasound Med 2015; 34 (12) 2253-2260
    CrossrefPubMedGoogle Scholar
  • 74 Abreu E, Aubert S, Wavreille G, Gheno R, Canella C, Cotten A. Peripheral tumor and tumor-like neurogenic lesions. Eur J Radiol 2013; 82 (1) 38-50
    CrossrefPubMedGoogle Scholar
  • 75 Lin J, Jacobson JA, Hayes CW. Sonographic target sign in neurofibromas. J Ultrasound Med 1999; 18 (7) 513-517
    CrossrefPubMedGoogle Scholar
  • 76 Ruiz A, Sala-Blanch X, Martinez-Ocón J, Carretero MJ, Sánchez-Etayo G, Hadzic A. Incidence of intraneural needle insertion in ultrasound-guided femoral nerve block: a comparison between the out-of-plane versus the in-plane approaches. Rev Esp Anestesiol Reanim 2014; 61 (2) 73-77
    CrossrefPubMedGoogle Scholar
  • 77 Brull R, Macfarlane AJ, Parrington SJ, Koshkin A, Chan VW. Is circumferential injection advantageous for ultrasound-guided popliteal sciatic nerve block?: A proof-of-concept study. Reg Anesth Pain Med 2011; 36 (3) 266-270
    CrossrefPubMedGoogle Scholar
  • 78 MacMahon PJ, Eustace SJ, Kavanagh EC. Injectable corticosteroid and local anesthetic preparations: a review for radiologists. Radiology 2009; 252 (3) 647-661
    CrossrefPubMedGoogle Scholar
  • 79 Gruber H, Glodny B, Kopf H , et al. Practical experience with sonographically guided phenol instillation of stump neuroma: predictors of effects, success, and outcome. AJR Am J Roentgenol 2008; 190 (5) 1263-1269
    CrossrefPubMedGoogle Scholar
  • 80 Abraham AM, Goff I, Pearce MS, Francis RM, Birrell F. Reliability and validity of ultrasound imaging of features of knee osteoarthritis in the community. BMC Musculoskelet Disord 2011; 12: 70
    CrossrefPubMedGoogle Scholar
  • 81 Taniguchi Y, Kumon Y, Takata T , et al. Imaging assessment of enthesitis in spondyloarthritis. Ann Nucl Med 2013; 27 (2) 105-111
    CrossrefPubMedGoogle Scholar
  • 82 Boutry N, Dupont S, Glaude E, Demondion X, Laffargue P, Cotten A. Segond fracture revealed by ultrasonography. J Ultrasound Med 2005; 24 (10) 1431-1435
    CrossrefPubMedGoogle Scholar
  • 83 Pearce T, Cobby M. Radiographically occult fracture of the tibial epiphysis: sonographic findings with CT correlation. J Clin Ultrasound 2011; 39 (7) 425-426
    CrossrefPubMedGoogle Scholar
  • 84 Blankstein A, Cohen I, Salai M, Diamant L, Chechick A, Ganel A. Ultrasonography: an imaging modality enabling the diagnosis of bipartite patella. Knee Surg Sports Traumatol Arthrosc 2001; 9 (4) 221-224
    CrossrefPubMedGoogle Scholar
  • 85 Murphey MD, Choi JJ, Kransdorf MJ, Flemming DJ, Gannon FH. Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics 2000; 20 (5) 1407-1434
    CrossrefPubMedGoogle Scholar
  • 86 Line BR. Pathophysiology and diagnosis of deep venous thrombosis. Semin Nucl Med 2001; 31 (2) 90-101
    CrossrefPubMedGoogle Scholar