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DOI: 10.1055/s-0036-1597832
Cardiac Arrest and Cardiopulmonary Resuscitation
Publication History
Publication Date:
01 February 2017 (online)
![](https://www.thieme-connect.de/media/sin/201701/lookinside/thumbnails/10-1055-s-0036-1597832_160068-1.jpg)
Abstract
In this review, the author summarizes the incidence, causes, and survival associated with out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). The resuscitation guideline process is outlined, and the impact of resuscitation interventions is discussed. The incidence of OHCA treated by emergency medical services varies throughout the world, but is in the range of 30 to 50 per 100,000 of the population. Survival-to-hospital-discharge rates also vary, but are in the range of 8 to 10% for many countries. Cardiac disease accounts for the vast majority of OHCAs; however, although it is a common cause of IHCAs, many other diseases are also common causes of IHCA. Five yearly reviews of resuscitation science have been facilitated in recent years by the International Liaison Committee on Resuscitation; these have been followed by the publication of regional resuscitation guidelines. There is good evidence that increasing rates of bystander cardiopulmonary resuscitation and earlier defibrillation are both contributing to improving the survival rate after an OHCA.
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References
- 1 Berdowski J, Berg RA, Tijssen JG, Koster RW. Global incidences of out-of-hospital cardiac arrest and survival rates: systematic review of 67 prospective studies. Resuscitation 2010; 81 (11) 1479-1487
- 2 Wissenberg M, Lippert FK, Folke F , et al. Association of national initiatives to improve cardiac arrest management with rates of bystander intervention and patient survival after out-of-hospital cardiac arrest. JAMA 2013; 310 (13) 1377-1384
- 3 Kudenchuk PJ, Redshaw JD, Stubbs BA , et al. Impact of changes in resuscitation practice on survival and neurological outcome after out-of-hospital cardiac arrest resulting from nonshockable arrhythmias. Circulation 2012; 125 (14) 1787-1794
- 4 Chan PS, McNally B, Tang F, Kellermann A ; CARES Surveillance Group. Recent trends in survival from out-of-hospital cardiac arrest in the United States. Circulation 2014; 130 (21) 1876-1882
- 5 Daya MR, Schmicker RH, Zive DM , et al; Resuscitation Outcomes Consortium Investigators. Out-of-hospital cardiac arrest survival improving over time: results from the Resuscitation Outcomes Consortium (ROC). Resuscitation 2015; 91: 108-115
- 6 Nichol G, Thomas E, Callaway CW , et al; Resuscitation Outcomes Consortium Investigators. Regional variation in out-of-hospital cardiac arrest incidence and outcome. JAMA 2008; 300 (12) 1423-1431
- 7 Girotra S, van Diepen S, Nallamothu BK , et al. Regional variation in out-of-hospital cardiac arrest survival in the United States. Circulation 2016; 133: 2159-2168
- 8 Weisfeldt ML, Everson-Stewart S, Sitlani C , et al; Resuscitation Outcomes Consortium Investigators. Ventricular tachyarrhythmias after cardiac arrest in public versus at home. N Engl J Med 2011; 364 (4) 313-321
- 9 Kitamura T, Iwami T, Kawamura T , et al; Japanese Circulation Society Resuscitation Science Study Group. Nationwide improvements in survival from out-of-hospital cardiac arrest in Japan. Circulation 2012; 126 (24) 2834-2843
- 10 Cobb LA, Fahrenbruch CE, Olsufka M, Copass MK. Changing incidence of out-of-hospital ventricular fibrillation, 1980-2000. JAMA 2002; 288 (23) 3008-3013
- 11 Hulleman M, Berdowski J, de Groot JR , et al. Implantable cardioverter-defibrillators have reduced the incidence of resuscitation for out-of-hospital cardiac arrest caused by lethal arrhythmias. Circulation 2012; 126 (7) 815-821
- 12 Hulleman M, Zijlstra JA, Beesems SG , et al. Causes for the declining proportion of ventricular fibrillation in out-of-hospital cardiac arrest. Resuscitation 2015; 96: 23-29
- 13 Sandroni C, Nolan J, Cavallaro F, Antonelli M. In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival. Intensive Care Med 2007; 33 (2) 237-245
- 14 Peberdy MA, Kaye W, Ornato JP , et al. Cardiopulmonary resuscitation of adults in the hospital: a report of 14720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation. Resuscitation 2003; 58 (3) 297-308
- 15 Girotra S, Nallamothu BK, Spertus JA, Li Y, Krumholz HM, Chan PS ; American Heart Association Get with the Guidelines–Resuscitation Investigators. Trends in survival after in-hospital cardiac arrest. N Engl J Med 2012; 367 (20) 1912-1920
- 16 Chan PS, Berg RA, Spertus JA , et al; AHA GWTG-Resuscitation Investigators. Risk-standardizing survival for in-hospital cardiac arrest to facilitate hospital comparisons. J Am Coll Cardiol 2013; 62 (7) 601-609
- 17 Chen LM, Nallamothu BK, Spertus JA, Li Y, Chan PS ; American Heart Association's Get With the Guidelines-Resuscitation (formerly the National Registry of Cardiopulmonary Resuscitation) Investigators. Association between a hospital's rate of cardiac arrest incidence and cardiac arrest survival. JAMA Intern Med 2013; 173 (13) 1186-1195
- 18 Chan PS, Krein SL, Tang F , et al. Resuscitation practices associated with survival after in-hospital cardiac arrest: a nationwide survey. JAMA Cardiol 2016; 1 (2) 189-197
- 19 Nolan JP, Soar J, Smith GB , et al; National Cardiac Arrest Audit. Incidence and outcome of in-hospital cardiac arrest in the United Kingdom National Cardiac Arrest Audit. Resuscitation 2014; 85 (8) 987-992
- 20 Harrison DA, Patel K, Nixon E , et al; National Cardiac Arrest Audit. Development and validation of risk models to predict outcomes following in-hospital cardiac arrest attended by a hospital-based resuscitation team. Resuscitation 2014; 85 (8) 993-1000
- 21 Peberdy MA, Ornato JP, Larkin GL , et al; National Registry of Cardiopulmonary Resuscitation Investigators. Survival from in-hospital cardiac arrest during nights and weekends. JAMA 2008; 299 (7) 785-792
- 22 Robinson EJ, Smith GB, Power GS , et al. Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study. BMJ Qual Saf 2015; bmjqs-2015-004223
- 23 Shao F, Li CS, Liang LR , et al. Incidence and outcome of adult in-hospital cardiac arrest in Beijing, China. Resuscitation 2016; 102: 51-56
- 24 Engdahl J, Holmberg M, Karlson BW, Luepker R, Herlitz J. The epidemiology of out-of-hospital ‘sudden’ cardiac arrest. Resuscitation 2002; 52 (3) 235-245
- 25 Myerburg RJ, Junttila MJ. Sudden cardiac death caused by coronary heart disease. Circulation 2012; 125 (8) 1043-1052
- 26 Larsen JM, Ravkilde J. Acute coronary angiography in patients resuscitated from out-of-hospital cardiac arrest--a systematic review and meta-analysis. Resuscitation 2012; 83 (12) 1427-1433
- 27 Perkins GD, Lall R, Quinn T , et al; PARAMEDIC trial collaborators. Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial. Lancet 2015; 385 (9972): 947-955
- 28 Kitamura T, Kiyohara K, Sakai T , et al. Epidemiology and outcome of adult out-of-hospital cardiac arrest of non-cardiac origin in Osaka: a population-based study. BMJ Open 2014; 4 (12) e006462
- 29 Bergum D, Nordseth T, Mjølstad OC, Skogvoll E, Haugen BO. Causes of in-hospital cardiac arrest - incidences and rate of recognition. Resuscitation 2015; 87: 63-68
- 30 Soar J, Nolan JP, Böttiger BW , et al; Adult advanced life support section Collaborators. European Resuscitation Council Guidelines for Resuscitation 2015: Section 3. Adult advanced life support. Resuscitation 2015; 95: 100-147
- 31 Nolan J, Soar J, Eikeland H. The chain of survival. Resuscitation 2006; 71 (3) 270-271
- 32 Søreide E, Morrison L, Hillman K , et al; Utstein Formula for Survival Collaborators. The formula for survival in resuscitation. Resuscitation 2013; 84 (11) 1487-1493
- 33 Nadkarni VM, Nolan JP, Billi JE , et al. Part 2: International collaboration in resuscitation science: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation 2010; 122 (16, Suppl 2) S276-S282
- 34 Morley PT, Lang E, Aickin R , et al. Part 2: Evidence evaluation and management of conflicts of interest: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Resuscitation 2015; 95: e33-e41
- 35 GRADE Handbook. Available at: http://www.guidelinedevelopment.org/handbook/ . Accessed May 6, 2015
- 36 Nolan JP, Hazinski MF, Aickin R , et al. Part 1: Executive summary: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Resuscitation 2015; 95: e1-e31
- 37 Hazinski MF, Nolan JP, Aickin R , et al. Part 1: Executive Summary: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation 2015; 132 (16, Suppl 1) S2-S39
- 38 Monsieurs KG, Nolan JP, Bossaert LL , et al; ERC Guidelines 2015 Writing Group. European Resuscitation Council Guidelines for Resuscitation 2015: Section 1. Executive summary. Resuscitation 2015; 95: 1-80
- 39 Neumar RW, Shuster M, Callaway CW , et al. Part 1: Executive summary: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2015; 132 (18, Suppl 2) S315-S367
- 40 Perkins GD, Handley AJ, Koster RW , et al; Adult basic life support and automated external defibrillation section Collaborators. European Resuscitation Council Guidelines for Resuscitation 2015: Section 2. Adult basic life support and automated external defibrillation. Resuscitation 2015; 95: 81-99
- 41 Hüpfl M, Selig HF, Nagele P. Chest-compression-only versus standard cardiopulmonary resuscitation: a meta-analysis. Lancet 2010; 376 (9752): 1552-1557
- 42 Pantazopoulos C, Xanthos T, Pantazopoulos I, Papalois A, Kouskouni E, Iacovidou N. A review of carbon dioxide monitoring during adult cardiopulmonary resuscitation. Heart Lung Circ 2015; 24 (11) 1053-1061
- 43 Nolan JP, Perkins GD, Soar J. Improving survival after out-of-hospital cardiac arrest. BMJ 2015; 351: h4989
- 44 Kudenchuk PJ, Brown SP, Daya M , et al. Amiodarone, lidocaine, or placebo in out-of-hospital cardiac arrest. N Engl J Med 2016; 374: 1711-1722
- 45 Hasselqvist-Ax I, Riva G, Herlitz J , et al. Early cardiopulmonary resuscitation in out-of-hospital cardiac arrest. N Engl J Med 2015; 372 (24) 2307-2315
- 46 Ringh M, Rosenqvist M, Hollenberg J , et al. Mobile-phone dispatch of laypersons for CPR in out-of-hospital cardiac arrest. N Engl J Med 2015; 372 (24) 2316-2325
- 47 Iwami T, Kitamura T, Kiyohara K, Kawamura T. Dissemination of chest compression-only cardiopulmonary resuscitation and survival after out-of-hospital cardiac arrest. Circulation 2015; 132 (5) 415-422
- 48 Nichol G, Leroux B, Wang H , et al; ROC Investigators. Trial of continuous or interrupted chest compressions during CPR. N Engl J Med 2015; 373 (23) 2203-2214
- 49 Blom MT, Beesems SG, Homma PC , et al. Improved survival after out-of-hospital cardiac arrest and use of automated external defibrillators. Circulation 2014; 130 (21) 1868-1875
- 50 Berdowski J, Blom MT, Bardai A, Tan HL, Tijssen JG, Koster RW. Impact of onsite or dispatched automated external defibrillator use on survival after out-of-hospital cardiac arrest. Circulation 2011; 124 (20) 2225-2232
- 51 Valenzuela TD, Roe DJ, Nichol G, Clark LL, Spaite DW, Hardman RG. Outcomes of rapid defibrillation by security officers after cardiac arrest in casinos. N Engl J Med 2000; 343 (17) 1206-1209
- 52 Waalewijn RA, Tijssen JG, Koster RW. Bystander initiated actions in out-of-hospital cardiopulmonary resuscitation: results from the Amsterdam Resuscitation Study (ARRESUST). Resuscitation 2001; 50 (3) 273-279
- 53 Valenzuela TD, Roe DJ, Cretin S, Spaite DW, Larsen MP. Estimating effectiveness of cardiac arrest interventions: a logistic regression survival model. Circulation 1997; 96 (10) 3308-3313
- 54 Larsen MP, Eisenberg MS, Cummins RO, Hallstrom AP. Predicting survival from out-of-hospital cardiac arrest: a graphic model. Ann Emerg Med 1993; 22 (11) 1652-1658