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CC BY-NC-ND 4.0 · J Neurol Surg Rep 2017; 78(01): e9-e11
DOI: 10.1055/s-0036-1597599
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Anterior Skull Base Glomangioma-Induced Osteomalacia

Malia S. Gresham
1   Department of Otolaryngology—Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States
,
Steven Shen
2   Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, United States
,
Yi J. Zhang
3   Division of Neurological Surgery, Department of Neurosurgery, Houston Methodist Hospital, Houston, Texas, United States
,
Kelly Gallagher
4   Department of Otolaryngology—Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States
› Author Affiliations
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Publication History

30 June 2016

07 November 2016

Publication Date:
30 January 2017 (online)

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Abstract

Oncogenic osteomalacia (OO) is an uncommon but treatable cause of osteomalacia related to tumor production of FGF23, usually caused by benign mesenchymal neoplasms. Paranasal sinus glomangiomas are a rare cause of OO, with only one previously reported case. Here we describe a second case (first reported in English) of paranasal sinus glomangioma-induced osteomalacia in a 42-year-old man. He presented with weakness and multiple spontaneous fractures, and was found to have an ethmoid sinus glomangioma with intracranial extension. The tumor was removed via endoscopic endonasal approach to the anterior skull base, which resulted in complete resolution of symptoms and no further evidence of disease 1 year postoperatively.

Keywords

oncogenic osteomalacia - glomangioma - paranasal sinus tumor - glomus tumor
 

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