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Semin Thromb Hemost 2016; 42(07): 741-751
DOI: 10.1055/s-0036-1593415
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Neonatal Hemostatic Disorders: Issues and Challenges

Santosh S. Hanmod   *
1   Department of Pediatrics and Human Development, MSU Center for Bleeding and Clotting Disorders, Michigan State University, East Lansing, Michigan
,
Rohith Jesudas   *
2   Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
,
Roshni Kulkarni
1   Department of Pediatrics and Human Development, MSU Center for Bleeding and Clotting Disorders, Michigan State University, East Lansing, Michigan
,
Meera Chitlur
2   Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
› Author Affiliations
Further Information

Publication History

Publication Date:
05 October 2016 (online)

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Abstract

Neonates form a unique cohort with distinct features associated with the hemostatic system compared with older children and adults. The development of the human hemostatic system begins around 10 weeks in utero and continues to evolve during childhood. This dynamic period termed developmental hemostasis should be taken into consideration when diagnosing a neonate with disorders of bleeding or thrombosis.

Keywords

neonate - hemostasis - bleeding - thrombosis - anticoagulation

* The authors Santosh S. Hanmod and Rohith Jesudas have contributed equally to this article.


 

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