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Synfacts 2017; 13(12): 1234
DOI: 10.1055/s-0036-1591623
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Asymmetric Transfer Hydrogenation in the Synthesis of Lorlatinib

Rezensent(en):
Philip Kocienski
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Publikationsdatum:
17. November 2017 (online)

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Key words

Lorlatinib - ALK inhibitor - Noyori asymmetric transfer hydrogenation - directed ortho-metalation - ketoreductase