Asymmetric Synthesis of Ipatasertib

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Synfacts 2017; 13(12): 1229
DOI: 10.1055/s-0036-1591619

Synthesis of Natural Products and Potential Drugs

Contributor(s):

Philip Kocienski

Further Information

Publication Date:
17 November 2017 (online)

Ipatasertib - Akt kinase inhibitor - biotransformation - nitrilase-catalyzed resolution - ketoreductase reduction - asymmetric hydrogenation