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Synfacts 2017; 13(06): 0566
DOI: 10.1055/s-0036-1590391
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of AZD8931 (Sapatinib)

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
16 May 2017 (online)

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Key words

AZD8931 - sapatinib - erbB inhibitor - aminoquinazolines - Dimroth rearrangement - nitration