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Synfacts 2016; 12(11): 1115
DOI: 10.1055/s-0036-1589290
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (R)-Sitagliptin

Authors

    Contributor(s):

  • Philip Kocienski

Further Information

Publication History

Publication Date:
18 October 2016 (online)

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Key words

sitagliptin - DPP-4 inhibitor - asymmetric Mannich reaction - β-amino acids - dithiomalonates - organocatalysis