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Synlett 2017; 28(07): 847-850
DOI: 10.1055/s-0036-1588401
DOI: 10.1055/s-0036-1588401
letter
Metal-Free Visible-Light-Mediated Desulfurization and Aromatization of Dihydropyrimidine-2-thiones for Synthesis of 2-Unsubstituted Pyrimidines
Weitere Informationen
Publikationsverlauf
Received: 02. November 2016
Accepted after revision: 31. Dezember 2016
Publikationsdatum:
19. Januar 2017 (online)
![](https://www.thieme-connect.de/media/synlett/201707/lookinside/thumbnails/st-2016-w0743-l_10-1055_s-0036-1588401-1.jpg)
Abstract
The visible-light-mediated aerobic desulfurization and aromatization of Biginelli 3,4-dihydropyrimidine-2(1H)-thiones for a one-step synthesis of 2-unsubstituted pyrimidines was established. The protocol uses molecular oxygen as an inexpensive oxidant, with visible-light irradiation, and eosin B as an organophotoredox catalyst.
Key words
photoredox reactions - organocatalysis - desulfurization - aromatization - dihydropyrimidinethionesSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0036-1588401.
- Supporting Information
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References and Notes
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