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Synlett 2017; 28(05): 601-606
DOI: 10.1055/s-0036-1588361
DOI: 10.1055/s-0036-1588361
letter
Rapid Ligand-Free Base-Accelerated Copper-Catalyzed Homocoupling Reaction of Arylboronic Acids
Weitere Informationen
Publikationsverlauf
Received: 19. August 2016
Accepted after revision: 30. Oktober 2016
Publikationsdatum:
17. November 2016 (online)
![](https://www.thieme-connect.de/media/synlett/201705/lookinside/thumbnails/st-2016-w0543-l_10-1055_s-0036-1588361-1.jpg)
Abstract
A rapid, ligand-free, base-accelerated, copper-catalyzed homocoupling reaction of (het)arylboronic acids is presented. A CuCl2·2H2O/Na2CO3-based catalyst enabled the formation of bi(het)aryl compounds by a homocoupling process in moderate to excellent yields (72–97%) within 15 minutes. A mechanism for the copper-catalyzed base-accelerated reaction is proposed.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0036-1588361.
- Supporting Information
-
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